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481
High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
Published 2023“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”
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482
Protein and glucose metabolism in response to hyperinsulinemia with and without hyperaminoacidemia in men with type 2 diabetes mellitus
Published 2011“…The presence of insulin resistance of protein in T2DM men has important implications for dietary protein recommendations as it suggests their protein requirements may be greater than current DRIs. Further investigation is warranted to address this issue in women and whether other dietary interventions known to improve insulin resistance of glucose metabolism in T2DM would modulate that of protein metabolism.…”
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483
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
Published 2024“…Additionally, we introduced two new metrics to our reporting: prevalence of unsuppressed viraemia (PUV), which represents the proportion of the population without a suppressed level of HIV (viral load <1000 copies per mL), and period lifetime probability of HIV acquisition, which quantifies the hypothetical probability of acquiring HIV for a synthetic cohort, a simulated population that is aged from birth to death through the set of age-specific incidence rates of a given time period. FindingsGlobal new HIV infections decreased by 21·9% (95% UI 13·1–28·8) between 2010 and 2021, from 2·11 million (2·02–2·25) in 2010 to 1·65 million (1·48–1·82) in 2021. …”
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484
Assessment of resin systems as solution for well integrity challenge in carbonate reservoirs
Published 2023“…Additionally, the transit time showed a 26–42% range decrease in the travel period, indicating that the cement was stronger under increased pressure and temperature. …”
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485
Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
Published 2020“…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. Therefore, polypharmacy can lead to poor health status and higher rates of morbidity and mortality. …”
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486
Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
Published 2020“…</p><h3>Results </h3><p dir="ltr">Out of 5639 patients screened, 75.5% (95% CI: 74.3–76.6) were exposed to polypharmacy. Females were 1.18 times more likely to have polypharmacy compared to males (95% CI: 1.03–1.34). …”
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487
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
Published 2021“…Next, we devised a method for semi-automated and blinded quantification of motor impairment for a population of simultaneously recorded animals with multi-worm tracking and custom image processing. …”
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488
Long-Haul Northeast Travel Disrupts Sleep and Induces Perceived Fatigue in Endurance Athletes
Published 2018“…After this time, sleep duration returned to baseline for several days until it was very likely decreased on the night prior to competition (-1.2 ± 1.0 h; 1.18; ±0.93). …”
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489
Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District
Published 2021“…Moreover, daylighting analysis shows decreased average illuminance levels from 407.8 to 154.97 Lux, equivalent to a 60% reduction in December and June. …”
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490
Application of Emotional Intelligence in Surgical Education: A Scoping Review
Published 2025“…<h3>Background</h3><p dir="ltr">Emotional Intelligence (EI) encompasses the ability to perceive, understand, and manage emotions and is increasingly recognized as a vital nontechnical (soft) skill within surgical education. …”
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491
Genomic Landscape And Structural Impact Of Biotinidase (BTD) Variants In A Middle Eastern Population
Published 2025“…MD simulations indicated that H323R, D444H, and P497S exhibited greater structural flexibility (increased RMSD/RMSF and PCA trace values), whereas R209C and D444H demonstrated reduced compactness (higher radius of gyration). …”
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Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare
Published 2021“…The results revealed that the new tool is beneficial, and the median times to finish the processes within the patient’s journey have significantly decreased. …”
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494
Impact of the positive pressure valve on vascular access device occlusions and bloodstream infections
Published 2009“…With this potential for improving patient outcomes, decreasing costs, and facilitating nursing care and catheter management, the use of PPV devices becomes both advantageous and desirable. …”
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495
Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
Published 2010“…This difference is because patients treated at such centers often present with large tumor size,8 underlying liver disease,9 and chemotherapy-associated hepatic toxicity.10 In an effort to reduce the need for blood transfusions in patients undergoing liver resection, we developed a 2-surgeon technique to optimize parenchymal transection.11 In our preliminary series,11 the combined use of saline-linked cautery and ultrasonic dissection was shown to be safe and to reduce blood loss, operation time, and time of inflow occlusion. The objective of this study was to evaluate, in our experience over a 10-year period, factors predictive of blood transfusion in patients who underwent liver resection. …”
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496
Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function
Published 2017“…Conversely, knock-down of MMP-8 in N-1089 reduced adhesion and increased migration. Expression of MMP-8 WT in β6-1089 led to greater localisation of α6β4 to HD and reduced retraction fibre formation, this being reversed by MMP-8 knock-down in N-1089. …”
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497
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”
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498
Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients
Published 2015“…Nearly 25% of patients with colorectal cancer have colorectal liver metastases (CLM) diagnosed at the same time the primary tumor is diagnosed (synchronous presentation). …”
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