Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Stein Emil, Vollset

“…We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternative scenarios assessing disease burden trajectories if selected sets of risk factors were eliminated from current levels by 2050. …”
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Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 by Joan B Soriano (6458528)

“…Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578–4 044 819) in 2017, an increase of 18·0% since 1990, while total DALYs increased by 13·3%. …”

Clinical characteristics and treatment outcomes of coats disease in a Saudi Arabian population by Al-Qahtani, Abdullah

“…Results: The most common presenting complaint was decreased visual acuity followed by strabismus and then leukocoria. …”
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From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease by Ahmad Raza (18205961)

“…This review focuses on the potential mechanisms associated with these two diseases, like insulin resistance, inflammation, oxidative damage, mitochondrial injury, and cell death. …”

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar by Shuja Mohd Reagu (12051406)

“…Breastfeeding requires close physical contact and observance of hygienic measures like handwashing. Worries around contamination increase during the perinatal period and can be expressed as increase in obsessive compulsive symptoms. …”

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 by Hmwe Hmwe Kyu (8674014)

“…Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). …”

Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults by Khaddaj, Rashel

“…After three-months supplementation of 50,000IU, vitamin D levels increased to 51.41 ±11.27ng/ml in the supplemented group and to24.95 ±6.45ng/ml in placebo group (p=0.00). PHQ-9 scores decreased from 12.53 ±5.33 to 4.92 ±2.44 in vitamin D group (p <0.001), and from 12.46 ±4.66 to 8.96±3.75in the control group (p<0.001), indicating enhancement in depressive symptomatology. …”
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The effect of microbiome therapy on COVID-19-induced gut dysbiosis: A narrative and systematic review by Mahmoud Yousef (9900837)

“…Further, bidirectional communication between the gastrointestinal tract and vital organs like the lung, heart, brain, and liver can exacerbate the disease severity and cause further inflammation and dysbiosis. …”

Novel proteins implicated in lipid metabolism disorders by Nature Research (16552612)

“…After feeding, its expression is decreased, promoting the uptake of dietary lipids in fat tissue. …”

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”

Biomarkers show promise for treatment of heart valve disease by Nature Research (16552612)

“…They are also comparing the levels of valve tissue markers with microRNAs and toll-like receptors, proteins involved in the immune system, in experimentally produced aortic stenosis in rabbits.…”

Business Continuity Management Maturity Model for Banks in UAE by Mahal, Ashish

“…They are faced with increasing levels of global competition, demanding customers and employees, shrinking product lifecycles and decreasing acceptable response times (Lockamy & McCormack, 2004) They have employees and deal with clients, suppliers & vendors from all over the world. …”
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Joseph L Ward (9715619)

“…Furthermore, indirect effects of the COVID-19 pandemic are likely to jeopardise efforts to improve health outcomes including mortality in young people aged 10–24 years. …”

The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar by Komal Rafique (17075074)

“…Our study aims to investigate the effect of metformin when given to women with GDM and additional risk factors for FGR like hypertension, inherited or acquired thrombophilia, anemia, and autoimmune disorders such as anti-phospholipid syndrome, lupus erythematosus.…”

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership by JASIM, ARIF FADHEL AHMED

“…The author’s line of argument is that conceptual skills are likely to play a significant role in ambidexterity leadership for innovation. …”
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Assessing Energy Saving Potential in Existing Buildings in Abu Dhabi through Passive Retrofitting Strategies: Case Study –Office Buildings by Manneh, Abeer

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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…<p dir="ltr">Dysregulated epigenetic modifications are common in lung cancer but have been reversed using demethylating agent like 5-Aza-CdR. 5-Aza-CdR induces/upregulates the NY-ESO-1 antigen in lung cancer. …”

Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease St... by Jessica A, Kerr

“…From 2022 to 2050, global increases in overweight (not obesity) prevalence are forecasted to stabilise, yet the increase in the absolute proportion of the global population with obesity is forecasted to be greater than between 1990 and 2021, with substantial increases forecast between 2022 and 2030, which continue between 2031 and 2050. …”
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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Alize J, Ferrari

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