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441
Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function
منشور في 2017"…Conversely, knock-down of MMP-8 in N-1089 reduced adhesion and increased migration. Expression of MMP-8 WT in β6-1089 led to greater localisation of α6β4 to HD and reduced retraction fibre formation, this being reversed by MMP-8 knock-down in N-1089. …"
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442
A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater
منشور في 2011"…Lymph node involvement was predictive of recurrence and decreased survival. Conclusion Patients with malignant tumors often present with jaundice and larger tumors. …"
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article -
443
Effect of climate change on the annual energy consumption of a single family house in British Columbia
منشور في 2018"…The Earth is already experiencing some of the effects of climate change, such as rising temperature, more frequent storms, increased precipitation, etc. …"
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444
Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth
منشور في 2021"…The lowest number of functional groups occurred in the early ages (2–3 years old), and some groups either increased or decreased their frequency and abundance along the years. …"
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article -
445
Essays on international environmental policy
منشور في 2009"…With the growing talk about the need to establish a new framework to deal with international environmental governance, it becomes relevant to shed some light on the interconnected landscape that characterizes environmental policy making. …"
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masterThesis -
446
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447
Fraud
منشور في 2017"…Additional testing that is over and above their responsibilities is being done in some cases due to auditors' concerns for their reputation. …"
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article -
448
Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
منشور في 2020"…Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578–4 044 819) in 2017, an increase of 18·0% since 1990, while total DALYs increased by 13·3%. …"
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449
Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
منشور في 2022"…Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). …"
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450
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
منشور في 2022"…This study demonstrates that biochar application at 2–6% is an effective means to increase chickpea yield and reduce water stress. Given small differences in performance within this application range, 2% application is recommended. …"
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451
Automatic image quality evaluation in digital radiography using for‐processing and for‐presentation images
منشور في 2024"…</p><h3>Methods</h3><p dir="ltr">A custom‐made phantom constructed according to the instructions given in the IAEA Human Health Series No.39 publication was used, along with the respective software that automatically calculates various IQ metrics. …"
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452
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453
Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties
منشور في 2022"…Soot particles, released during diesel combustion, adversely affect human health and the environment. Some studies suggest blending diesel with oxygenated fuels to reduce soot emissions, though it also reduces fuel economy and may produce new pollutants such as aldehydes. …"
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454
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …"
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455
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
منشور في 2022"…<p>Loss of function mutations in store-operated Ca<sup>2+</sup> entry (SOCE) are associated with severe paediatric disorders in humans, including combined immunodeficiency, anaemia, thrombocytopenia, anhidrosis and muscle hypotonia. Given its central role in immune cell activation, SOCE has been a therapeutic target for autoimmune and inflammatory diseases. …"
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456
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
منشور في 2022"…<p dir="ltr">Transport of fine particles in porous media has attracted a considerable interest over the past several decades given its importance to many industrial and natural processes. …"
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457
Energy saving potential analysis applying factory scale energy audit – A case study of food production
منشور في 2023"…The results of a preliminary energy audit carried out at a sizable industrial facility in Jordan that creates some of the most well-known foods in the Middle East are presented in this study. …"
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article -
458
Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains
منشور في 1991"…These results are consistent with the hypothesis that the rats' resistance to MPTP neurotoxicity is to some extent a property of their unique brain endothelium which has high MAO activity.…"
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article -
459
Oxandrolone Treatment in Adults with Severe Thermal Injury
منشور في 2009"…However, most data on oxandrolone use in adult patients with severe thermal injury are derived from single-center studies, many of which enrolled a relatively small number of subjects and some of which had a poor design. Multicenter, prospective, randomized studies are needed to better define the optimal oxandrolone dosage and to confirm the efficacy and safety of this drug in adult patients with severe thermal injury.…"
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article -
460