Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration حسب Milane, Aline

"…Inflammation and Parkinson’s-like lesions induced by MPTP intoxication could lead to modification of drug pharmacokinetics and have clinical consequences, such as neurotoxicity.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Efficient multi-objective neural architecture search framework via policy gradient algorithm حسب Bo Lyu (16522643)

"…However, differentiable NAS methods encounter challenges when dealing with non-differentiable objectives like energy efficiency, resource constraints, and other non-differentiable metrics, especially under multi-objective search scenarios. …"

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant حسب Lei Zhang (38117)

"…The graphical simulations are performed for flow parameters with specific range like 1≤Re≤5, 1≤Ha≤5, 0.5≤Nt≤2.5, 1≤Nb≤3, 0.2≤Sc≤1.8, 0.2≤Pe≤1.0 and 0.2≤Ω≤1.0. …"

Resilience of UAE high-rise buildings to climate change: Impacts of projected climate changes on annual energy demands. حسب Sallam, Duaa

"…As global warming is hitting all areas in the entire world, designing and retrofitting buildings based on future weather conditions is essential to avoid early deterioration of buildings especially in countries with high air temperatures like UAE. This motivates the research on finding to most energy efficient solutions that would reduce energy consumption of UAE high-rise buildings in present and future weather conditions. …"
احصل على النص الكامل

Colon Cancer General Knowledge, Attitude and Awareness Channels: A Cross‐Sectional Study حسب Mu'taz Massad (22466734)

"…Awareness of colon cancer and its screening tools has a fundamental role in increasing screening participation. The information about Jordanians' awareness of colon cancer screening is inadequate.…"

Masked phenomenon: renal and cardiovascular complications; review and updates حسب Elmukhtar Habas (14777677)

"…The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). …"

Application of behavioural theories, models, and frameworks in pharmacy practice research based on published evidence: a scoping review حسب Zachariah Nazar (8600154)

"…</p><h3>Results</h3><p dir="ltr">Fifty articles met the inclusion criteria; a trend indicating an increasing frequency of behavioural theory/frameworks/models within pharmacy practice research was identified; the most frequently reported were Theory of Planned Behaviour and Theoretical Domains Framework. …"

Workforce localization in the UAE : recruitment and selection challenges and practices in private and public organizations حسب Waxin, Marie-France

"…Workforce localization (WL) has become an issue of increasing importance in the Arab Gulf region, a key emerging market, where, in many cases, local citizens are the minority in terms of population, and compete with high numbers of expatriate employees for jobs and positions. …"
احصل على النص الكامل

Review of field methods for monitoring Asian bears حسب Michael F., Proctor

"…Alternatively, careful use of local knowledge or expert opinion may be viable options, but come with greater uncertainty. For the foreseeable future, we believe that expert opinion will likely continue to play a large part in monitoring Asian bears, but these opinions should be informed by more rigorous data from the other methods we discuss.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage حسب Florence Hariton (18629764)

"…SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …"

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 حسب Olfa Khalifa (10914452)

"…MALAT1 has recently attracted attention for its role in the evolution of diabetic complications, since it has been demonstrated that MALAT1 dysregulation contributes to the pathogenesis of diabetes and liver disease. …"

Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study حسب Husham Abdelrahman (768893)

"…Patients 65 years or older were likely to have higher frailty scores, as indicated by higher percentages in the mFI-5. …"

Impact of the COVID-19 lockdown on lifestyle behaviors and their association with personality among adults in Qatar: A cross-sectional study حسب Tamara Al-Abdi (8710488)

"…The overall MD adherence decreased during lockdown (5.9 vs. 6.1, p < 0.001). …"

Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS حسب Myint Myint Aye (6404327)

"…<h3>Background</h3><p dir="ltr">Insulin resistance (IR) is the hallmark of PCOS and it is known that exercise may decrease it. What is unknown is whether exercise may mechanistically alter the underlying IR, attenuating the dynamic lipid induced IR in insulin resistant subjects.…"

Effect of surfactants on the convective heat transfer and pressure drop characteristics of ZnO/DIW nanofluids: An experimental study حسب Qamar, Adnan

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

NLRP7 inter-domain interactions حسب El Maarri, Osman

"…Mutations in NLRP7 (NOD-like-receptor family, pyrin domain containing 7) are responsible for a type of recurrent pregnancy loss known as recurrent hydatidiform mole (HYDM1). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation حسب Salman, Zeina

"…Flagellin (FliC), a major component of C. difficile flagella, plays a pivotal role in host-pathogen interactions by inducing inflammation via Toll-like receptor 5 (TLR5). MicroRNAs (miRNAs) are critical regulators of inflammation and may serve as therapeutic targets. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Seasonal variations of trace metal chemical forms in bed sediments of a karstic river in Lebanon حسب Korfali, Samira Ibrahim

"…All readily exchangeable metals decreased in winter and the carbonate bound forms predominated in both seasons. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Road safety and traffic medicine in Iran: Achievements and challenges حسب A. Motevalian (19807242)

"…The number of annual fatalities, which had been on the rise for several decades, reached to the maximum number of over 27500 deaths in 2005. The number decreased to 23000 in 2010 and less than 18000 in 2013. …"

Nebulized fentanyl for respiratory symptoms in patients with COVID-19 (ventanyl trial) حسب Nissar Shaikh (11659441)

"…Interventions such as oxygen therapy, oral opiates, and traditional nebulizers like ipratropium bromide and salbutamol are variable in their efficacy, and therapy responses in patients are difficult to predict. …"