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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…RNA-sequencing analysis further validated the findings by showing a significant increase in genes associated with lipid metabolism, bile acid secretion, and suggested the activation of hepatic stellate cells and hepatic fibrosis in MH lacking FOXA2. Overexpression of FOXA2 reversed the defective phenotypes and improved hepatocyte functionality in iPSC-derived hepatic cells lacking FOXA2. …”
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Risk at the margins
Published 2019“…In light of these issues, we quantitatively assess the landslide risk profile of Lebanon, finding a 75% increase in landslide risk since the start of the Syrian crisis. …”
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Engaging with readers: Students’ metalinguistic understanding of the use of pronouns in building reader-writer relationships
Published 2023“…<p>Students’ metalinguistic understanding of the written academic argument is important both to increase writer independence and inform writing instruction. …”
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Survival Misperceptions, Time Inconsistency, and Implications for Life-cycle Saving and Welfare
Published 2013“…In general equilibrium, however, such time inconsistent behavior with survival misperception is conducive to aggregate capital accumulation and greater equilibrium bequest income. The latter effects can produce substantial welfare gains. …”
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Evidence-based safety education and training for traffic injury prevention
Published 2015“…Bicycle skill training for children and youth may increase their safety knowledge, but not necessarily improve their behavior or decrease their injury rates. …”
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Initial risk assessment for pulmonary hypertension in patients with COPD
Published 2012“…Diffusion capacity was lower but did not reach statistical significance (P = 0.07). …”
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Managing Endothelial Dysfunction in COVID-19
Published 2022“…Conclusion Among patients hospitalized with mild, moderate, or severe COVID-19 infection, targeting endothelial dysfunction by administering Nicorandil, L-arginine, Folate, Nebivolol, and Atorvastatin on top of optimal medical therapy did not decrease time to recovery. However, this treatment protocol was associated with an excellent safety profile. …”
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
Published 2002“…On the other hand, a 3% alcohol consumption (as beer or whisky) maintained for a two months period did not have an effect on fasting plasma TAG concentration while total and LDL cholesterol concentrations showed a significant decrease and HDL cholesterol concentration was moderately increased. …”
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The impact of water table fluctuation and salinity on LNAPL distribution and geochemical properties in the smear zone under completely anaerobic conditions
Published 2023“…In fluctuating columns, pore water sulfate decreased in the middle, but in stable columns, it decreased in the first 40 days, which suggested that sulfate was the primary electron donor and sulfate-reducing bacteria were present. …”
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Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
Published 2021“…We found that SESN2 silencing, though did not specifically induce ER stress, it aggravated the effects of thapsigargin-induced ER stress on oxidative stress and cell survival. …”
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Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials
Published 2024“…Previous reviews suggested potential TXA benefits but did not consider the latest trials. MethodsA systematic review and bias-adjusted meta-analysis were performed to assess TXA’s effectiveness in emergency traumatic injury settings by pooling estimates from randomized controlled trials. …”
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Parallel Algorithm for Hardware Implementation of Inverse Halftoning
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Timing driven genetic algorithm for standard-cell placement
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The performance of banks in post-war Lebanon
Published 2004“…Although we find that Lebanese banks are profitable, most of them had accounting return on assets (ROA) greater than one percent over most of our test period, they are not as profitable as a control group of banks from five other countries located in the Middle East. …”
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A review of cleaner alternative fuels for maritime transportation
Published 2021“…<p>Environmental regulations have always been an essential component in the natural gas supply chain, with recent and greater emphasis on shipping operations. Recently more stringent regulations have been imposed by the International Maritime Organization on global maritime shipping operations. …”
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Insight into Faculty Open Access Perceptions: A Quantitative Analysis among UAE Faculty
Published 2022“…While there is a variety of extant literature broaching these perceptions, there are few quantitative analyses with an n greater than 100 respondents, and a notable lack of research in the United Arab Emirates (UAE). …”
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Arab women: No longer silent, but can they guarantee rights for themselves
Published 2012“…I will then discuss how political upheaval in the Arab region demonstrates a greater need for women/gender recognition and study. …”
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Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound
Published 2021“…These modifications allow nannocarriers to achieve greater targeting specificity through binding to specific receptors overexpressed on the surface of the tumor cells. …”
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