STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration حسب Ayat S. Hammad (9592374)

"…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca²⁺ entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …"

Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases حسب Glazer, Evan

"…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Numerical Investigation of Flexural Behavior of Reinforced Concrete (RC) T-Beams Strengthened with Pre-Stressed Iron-Based (FeMnSiCrNi) Shape Memory Alloy Bars حسب Khalil, Ahmed

"…Based on the numerical results, it was found that increasing the compression strength from 30 to 60 MPa slightly improves the beam’s strength (by 2%), but it significantly increases its ductility by approximately 45%. …"
احصل على النص الكامل

Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus حسب Bahous, Sola Aoun

"…Mortality was significantly greater among diabetic than nondiabetic hypertensive subjects (all-cause mortality, 14.05% versus 7.43%; and cardiovascular mortality, 1.28% versus 0.7%). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Five-Level MLI-Based Grid-Connected Photovoltaic Systems: A Review on Control Methodologies, Modulation Strategies and Recent Developments حسب Anurag Tiwari (3563561)

"…Five-level MLI-based PV systems have become a crucial option as the relevance of renewable energy keeps increasing because of their increased efficiency, less harmonic distortion, and greater power quality. …"

Impacts of Diverse Workforce on Cyber Security and Information Technology Management حسب ALHEBSI, WADDAH SULTAN

"…Despite these findings, organizations should continue to consider the potential benefits of diversity in the cybersecurity workforce, including improved decision-making, increased adaptability, enhanced creativity, greater representation, and improved team performance. …"
احصل على النص الكامل

Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways حسب Shehaby, Wassim N.

"…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma حسب Shebaby, W.

"…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effect of StarD13 on colorectal cancer proliferation, motility and invasion حسب Nasrallah, Anita

"…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Disciplinary action against physicians: Who is likely to get disciplined? حسب Dimassi, Hani

"…Kaplan-Meier analysis revealed that the proportion of physicians disciplined increased with each successive 10-year interval since first licensure. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Transnational activism in Lebanon's women's movement. (c2013) حسب Hage, Sandy S. El

احصل على النص الكامل
احصل على النص الكامل

Yeast Cell Adhesion Molecules Have Functional Amyloid-Forming Sequences حسب Khalaf, Roy A.

"…These sequences had an unusual amino acid composition: 77% of their residues were β-branched aliphatic amino acids Ile, Thr, and Val, which is more than 4-fold greater than their prevalence in the S. cerevisiae proteome. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Critical Review on Nanofluids: Preparation, Characterization, and Applications حسب Mohamoud Jama (19691638)

"…A “nanofluid” is a fluid with suspended fine nanoparticles which increases the heat transfer properties compared with the original fluid. …"

Potential of GTL-Derived Biosolids for Water Treatment: Fractionization, Leachate, and Environmental Risk Analysis حسب Shifa Zuhara (14150862)

"…Characterization showed an increased carbon content and reduced oxygen content in the biochar sample. …"

Diversity of hydrocarbon-degrading bacteria isolated from the rhizosphere of mangrove forests in two coastal regions of Qatar حسب Mona Yousefi (17679490)

"…In contrast, Al Thakhirah exhibited greater bacterial diversity, including <i>Lysinibacillus xylanilyticus</i> and <i>Acinetobacter calcoaceticus</i>. …"

The Effects of Emotional Decoding on Eliciting Empathic Responses in Language Teachers: An Idiodynamic Case Study حسب Tamimi, Alaa

احصل على النص الكامل

Effect of Basalt Microfiber on the Shear Response of RC Short Beams حسب Sabbagh, Mohamad Kusay Ahmad Rabee

احصل على النص الكامل

An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im... حسب Khreibi, Rima Abou

"…Zayed University-Dubai had greater STEM majors’ enrolments compared to Zayed University-Abu Dhabi. …"
احصل على النص الكامل

The Impact of Using Specialist Geotechnical Software in Modeling of Pile Raft Foundation (PRF) حسب SHOKR, MOHAMED

"…Piled Raft foundation (PRF) is formed by addition of piles to a Raft Foundation and it increases the load bearing capacity. Horizontal loads can be resisted to a maximum extent due to the addition of piles to a raft foundation. …"
احصل على النص الكامل

Framework for Mapping Internal Stakeholder Dynamics in Driving Green Innovation Strategies in the UAE Oil & Gas Sector حسب BASIONI, AHMED ALI

"…Global population and economic growth placed increasing pressure on natural resources, creating urgent environmental and sustainability challenges for resource-intensive industries. …"
احصل على النص الكامل