Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. We also concluded that autophagy was activated in response to arginine depletion and plays a protective role at early time points. …"
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) حسب Khalil, Nathalie

"…We have established that autophagy, a process of cellular destruction activated in response to arginine deprivation, can be the leading cause of cell death at late drug incubation times. Hence, our study demonstrates that HuArgI (Co)-PEG5000 is a novel, potent and selective potential therapeutic approach for PC.…"
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Colon Cancer General Knowledge, Attitude and Awareness Channels: A Cross‐Sectional Study حسب Mu'taz Massad (22466734)

"…Awareness of colon cancer and its screening tools has a fundamental role in increasing screening participation. The information about Jordanians' awareness of colon cancer screening is inadequate.…"

Masked phenomenon: renal and cardiovascular complications; review and updates حسب Elmukhtar Habas (14777677)

"…The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). …"

Application of behavioural theories, models, and frameworks in pharmacy practice research based on published evidence: a scoping review حسب Zachariah Nazar (8600154)

"…</p><h3>Results</h3><p dir="ltr">Fifty articles met the inclusion criteria; a trend indicating an increasing frequency of behavioural theory/frameworks/models within pharmacy practice research was identified; the most frequently reported were Theory of Planned Behaviour and Theoretical Domains Framework. …"

Workforce localization in the UAE : recruitment and selection challenges and practices in private and public organizations حسب Waxin, Marie-France

"…Workforce localization (WL) has become an issue of increasing importance in the Arab Gulf region, a key emerging market, where, in many cases, local citizens are the minority in terms of population, and compete with high numbers of expatriate employees for jobs and positions. …"
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Review of field methods for monitoring Asian bears حسب Michael F., Proctor

"…Alternatively, careful use of local knowledge or expert opinion may be viable options, but come with greater uncertainty. For the foreseeable future, we believe that expert opinion will likely continue to play a large part in monitoring Asian bears, but these opinions should be informed by more rigorous data from the other methods we discuss.…"
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties حسب Ovidiu, Ciobanu

"…ObjectiveThe aim of this study is to investigate how hydrogen peroxide (HP) treatments affect enamel porosity and protein structure, as well as their impact on tooth shade and hardness over time. MethodsFifty healthy teeth were collected from adult patients. …"
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Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... حسب Parkes J Kendrick (9714851)

"…Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. …"

Supplementation of retrobulbar block with clonidine in vitreoretinal surgery حسب Abi Nader, Elie

"…Conclusions The addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia.…"
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Influence of co-current vapor flow on falling film over horizontal tube حسب Furqan Tahir (14429547)

"…First, the liquid load is varied between 0.02 and 0.05 kg/(m·s), and its effects on the film thickness and the wetting time are calculated, presented and discussed. Afterwards, the impact of co-current vapor flow on film distribution, wetting time, minimum thickness and its location are quantified and examined by increasing the vapor velocity up to 6 m/s with 2 m/s intervals. …"

Sustainable Detoxification of Methylene Blue in Wastewater via Tea Residue Adsorption: Optimization and Kinetics حسب Farah F. Salameh (21797300)

"…The impact of various parameters on MB removal was assessed, including solution pH, adsorbent dosage, pollutant concentration, and contact time. Optimal conditions were identified as pH 10, a dosage of 4 g/L, a concentration of 100 mg/L, and a contact time of 2 h, achieving nearly 99% removal efficiency at 25 °C. …"

Self-Organization and Multi-Agent Reinforcement Learning for Taxi Dispatch حسب Alshamsi Omran, Aamena Ali Ahmed

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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels حسب Haya Al-Sulaiti (5449256)

"…Annotation of metabolites was determined by retention times and specific MRMs for each compound. Results indicate that AuNPs treatment significantly impacted several metabolic pathways. …"

Protein and glucose metabolism in response to hyperinsulinemia with and without hyperaminoacidemia in men with type 2 diabetes mellitus حسب Bassil, Maya Said

"…The presence of insulin resistance of protein in T2DM men has important implications for dietary protein recommendations as it suggests their protein requirements may be greater than current DRIs. Further investigation is warranted to address this issue in women and whether other dietary interventions known to improve insulin resistance of glucose metabolism in T2DM would modulate that of protein metabolism.…"
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties حسب Jelena Eric (21015107)

"…<h3>Objective</h3><p dir="ltr">The aim of this study is to investigate how hydrogen peroxide (HP) treatments affect enamel porosity and protein structure, as well as their impact on tooth shade and hardness over time. </p><h3>Methods</h3><p dir="ltr">Fifty healthy teeth were collected from adult patients. …"

Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts حسب Amr A. Fadle (14150298)

"…Secondary outcomes were operative time, time to union, and complications. The double arthrodesis was done through the medial approach, while the triple arthrodesis was done through dual medial and lateral approaches. …"

10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes حسب Goran Petrovski (129836)

"…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …"

Vitamin D association with coagulation factors in polycystic ovary syndrome is dependent upon body mass index حسب Abu Saleh Md Moin (6189512)

"…In addition, coagulation variables such as thrombin-activatable fibrinolysis inhibitor, plasminogen activator inhibitor-1 (PAI-1), D-dimer, Antithrombin and thrombomodulin have been reported to be elevated in PCOS compared to control subjects, and the functional coagulation tests including prothrombin time, thrombin time and fibrin degradation products may be predictive of PCOS. …"

Outcomes of POCUS‐Guided Peripheral Intravenous Access in Difficult Venous Access Patients: A Systematic Review and Meta‐Analysis حسب Hany A. Zaki (17337673)

"…A systematic review of 15 studies with 1485 patients, sourced from five databases, including PubMed, Cochrane Library, MEDLINE, Web of Science, and Google Scholar, showed POCUS significantly improved success rates (OR: 4.25), first‐attempt success (OR: 5.31), reduced attempts (MD: −0.83), and decreased procedure time (MD: −9.75 min). Fewer complications (OR: 0.49) observed with POCUS compared to standard techniques. …"