Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) حسب Khalil, Nathalie

"…Sensitivity to HuArgI (Co)- PEG5000-induced arginine deprivation was attributable to the complete dependence on exogenous arginine of two of the five PC cell lines tested and to the partial arginine auxotrophy in combination with fast proliferative requirements of the remaining three cell lines. The lack of ASS-1 expression was demonstrated to be the underlying cause behind complete arginine dependence. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Impact of severe hypoglycemia on the heat shock and related protein response حسب Alexander S. Atkin (18520107)

"…At baseline, MAPKAPK5 (p = 0.02) and UBE2G2 (p = 0.003) were elevated and STUB1 decreased (p = 0.007) in T2D. At hypoglycemia: PPP3CA (p < 0.03) was increased and EPHA2 (p = 0.01) reduced in T2D; by contrast, three proteins were reduced in controls [HSPA1A (p = 0.007), HSPB1 (p < 0.02), SMAD3 (p = 0.005)] while only MAPKAPK5 was elevated (p = 0.02). …"

Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases حسب Pawlik, Timothy

"…Adverse preoperative biologic factors including tumor number greater than 3 (P = 0.01) and a preoperative CEA level greater than 200 ng/mL (P = 0.04) were associated with an increased risk of positive surgical margin. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

MRP4 حسب Abi-Gerges, Aniella

"…Application of ISO (1nM) induced a similar increase in cAMP level in WT and MRP4 KO mice (YFP/CFP: 4.4 ± 0.15 in WT vs 4.1 ± 0.44 in KO cells), whereas cAMP signal was greater in MRP4 KO compared to WT mice after PDE inhibition by IBMX (ISO 1nM + IBMX 300µM: 8.1 ± 0.6 in WT vs 11.8 ± 0.62 in KO cells; p<0.01). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Islamist groups in Tripoli. (c2008) حسب Abbas, Nivine H.

احصل على النص الكامل
احصل على النص الكامل

Integration of Smart Sensors in Buildings to achieve Energy Efficiency in Hot and Humid Climate حسب JABR, BILAL SUDQI SAEED

"…It is also estimated that this utilization would grow to above 50% by 2030 because of the fast and consistent growth in economic activity and increase in population around the world. People tend to spend the greater part of their time in indoor spaces e.g., commercial and residential buildings. …"
احصل على النص الكامل

“Enhanced Forced Convection Heat Transfer from a Cylinder using Permeable Fins, حسب Abu-Hijleh, Bassam

"…The ratio between the permeable to solid Nusselt numbers increased with Reynolds number and fin height but tended to decrease with number of fins. This ratio was as high as 4.35 at Reynolds number of 150 and a single fin with a nondimensional height of 3.0. …"
احصل على النص الكامل

Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat حسب Ahmed Hussein (683680)

"…The samples with <i>F</i>. tataricum demonstrated greater amounts of fiber and ash while the samples made of soft wheat flour were rich in carbohydrates. …"

Knee Angle Affects Posterior Chain Muscle Activation During an Isometric Test Used in Soccer Players حسب Paul James Read (14152221)

"…These differences (30% mean difference) were greater than the observed typical measurement error (CV% = 13.1–14.3 for the 90° and 30° test positions, respectively). …"

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension حسب Thiruveni Ramkumar (17075051)

"…<h3>Objective</h3> <p>The study aims to identify and evaluate the relationships between unmodifiable and potentially modifiable factors in hypoglycemic neonates with hypertensive mothers. …"

Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy حسب Yahya, Fares

احصل على النص الكامل

Zirconium phytate-based proton conductors for high-temperature fuel cell applications حسب Nimir, Wessam Ahmed Mohamed

احصل على النص الكامل

Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels حسب Haya Al-Sulaiti (5449256)

"…Rats (n = 14) were divided into three groups: control (<i>n</i>= 2), AuNPs (<i>n</i>= 6) and AgNPs (<i>n</i>= 6), to mimic potential biomedical exposure scenarios. …"

Impact of birth weight to placental weight ratio and other perinatal risk factors on left ventricular dimensions in newborns: a prospective cohort analysis حسب Ashraf Gad (17040114)

"…Chi-squared and one-way analysis of variance were used to compare BW/PW groups and the best regression model was selected using a genetic and backward stepwise algorithm.</p><h3>Results</h3><p dir="ltr">We analyzed 827 neonates in three BW/PW groups: small (n=16), normal (n=488), and large (n=323). …"

Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study حسب Husham Abdelrahman (768893)

"…<h3>Background</h3><p dir="ltr">Using a validated tool, we explored the prevalence, risk factors, and predictors of longer hospitalization among hospitalized geriatric patients.…"

Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study حسب Mona Abdi (10196665)

"…Moreover, homozygous variants were found in 7 families (25.9%), with a sixfold increase in homozygous burden in consanguineous versus non-consanguineous families (13.6% and 1.8%, respectively). …"

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis حسب Meritxell Espino‐Guarch (22565774)

"…The absence of LAT2 led to increased intramuscular glutamine (Gln) accumulation (6.3‐fold, <i>p</i> < 0.0001), accompanied by a reduction in skeletal muscle proteolysis during fasting (0.61‐fold, <i>p</i> = 0.0004) primarily due to decreased proteasomal and autophagic activity (0.45‐fold, <i>p</i> = 0.016 and 0.7‐fold, <i>p</i> = 0.002, respectively). …"

Optimum sizing of steam turbines for concentrated solar power plants حسب Poullikkas, Andreas

"…Thus, there is significant efficiency gains to be realized and large cost savings in increasing the turbine size up to 50MWe. Finally, although the cost of electricity of a CSP plant with capacities greater than 1MWe is significantly reduced to less than 1US$/kWh, currently such technology can only become economically viable through supporting schemes.…"
احصل على النص الكامل

The benefits of employees' empowerment حسب Armache, Jalal

"…More responsibility generates greater productivity, and commitment. Most employees were more productive when empowered by management; almost all firms recognize the importance of increased employee performance and measure it. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Kumaraswamy Pareto IV Distribution حسب Tahir, M. H.

"…It has increasing, decreasing, upside-down bathtub, bathtub, J and reversed-J shaped hazard rate shapes. …"
احصل على النص الكامل