Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans حسب Kevin S. Chen (9201767)

"…There is an urgent need for disease-modifying therapies for Parkinson’s disease, but drug discovery is challenged by lack of in vivo models that recapitulate early stages of neurodegeneration. …"

Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare حسب ALQUDAH, ADI AHMAD ALI

"…A quick review of the literature showed a lack of studies that discuss the acceptance of QMS. …"
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Assessing Energy Saving Potential in Existing Buildings in Abu Dhabi through Passive Retrofitting Strategies: Case Study –Office Buildings حسب Manneh, Abeer

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Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 حسب Comfort, Haley

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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 حسب Stein Emil, Vollset

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Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease St... حسب Jessica A, Kerr

"…From 2022 to 2050, global increases in overweight (not obesity) prevalence are forecasted to stabilise, yet the increase in the absolute proportion of the global population with obesity is forecasted to be greater than between 1990 and 2021, with substantial increases forecast between 2022 and 2030, which continue between 2031 and 2050. …"
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Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 حسب Austin, Carter

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Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17 حسب Aniruddha Deshpande (4377094)

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 حسب Kanyin Liane, Ong

"…By 2050, 89 (43·6%) of 204 countries and territories will have an age-standardised rate greater than 10%. InterpretationDiabetes remains a substantial public health issue. …"
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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... حسب Marissa B Reitsma (8674341)

Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud... حسب Robert C Reiner (5147636)

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Bur... حسب Rafael, Lozano

"…Global ambitions to accelerate progress on UHC service coverage are increasingly unlikely unless concerted action on non-communicable diseases occurs and countries can better translate health spending into improved performance. …"
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An efficient failure-resilient mutual exclusion algorithm for distributed systems leveraging a novel zero-message overlay structure حسب Mouna Rabhi (17086969)

"…An extensive simulation study demonstrates the viability and efficiency of the proposed algorithm under various node failure models, and relevant metrics (e.g., node queue dimension, number of exchanged messages, and number of disconnected nodes) indicate a graceful degradation in performance with decreasing number of functioning nodes. For instance, for 4,096 nodes organized in a logical tree of arity 4 and with 4 physical nodes for logical node, a negligible number of nodes is disconnected from the tree after 250 epochs when the per-node per-epoch failure probability is p f ≤ 0 . 0008 . …"

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Bur... حسب Rafael Lozano (234333)

"…Global ambitions to accelerate progress on UHC service coverage are increasingly unlikely unless concerted action on non-communicable diseases occurs and countries can better translate health spending into improved performance. …"

Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis حسب Allgayer, Heike

"…In patients who underwent curative resection, a significant correlation with a decreased disease-free survival rate was found (P < 0.0001). …"
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Effects of visual field impairment on driving حسب Jan Andersson (218600)

Muscle protein anabolism in type 2 diabetes حسب Bassil, Maya S.

"…One study of chronic leucine supplementation in elderly T2DM patients did not increase muscle mass. However, they lacked sarcopenia and had adequate dietary protein intake, so may be atypical. …"
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Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up حسب Wahiba Elhag (5245547)

"…<h2>Background</h2> <p>Long-term durability of weight loss and comorbidity resolution beyond 7 years after laparoscopic sleeve gastrectomy (LSG) among adolescents is completely lacking.</p> <h2>Methods</h2> <p>Retrospective review of adolescents aged ≤ 18 years who underwent primary LSG at our institution between 2011 and 2015 (N = 146). …"

Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts حسب Mustafa T. Ardah (4858657)

"…In an in-vitro cell model, these compounds decreased the insoluble phosphorylated α-syn and aggregation. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…We hypothesized that mice lacking DNAJB3 would be more prone to high-fat (HF)-diet-induced increase in body weight and body fat, inflammation, glucose intolerance and insulin resistance as compared with wild-type (WT) littermates. …"