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Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
Published 2019“…<p dir="ltr">Metformin, the most widely used anti-diabetic drug, also exhibits anti-cancer properties; however, the true potential of metformin as an anticancer drug remains largely unknown. …”
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142
Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
Published 2019“…Second, we examined symptom queries preceding queries on the 12-step program at time lags of 0-7 days, 7-14 days, and 14-30 days, where the probability of asking about a medical symptom was greater in the 30-day time window preceding 12-step program information-seeking as compared to all previous times that the symptom was queried.…”
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143
Effect of Crude Oil Products on the Geotechnical Properties of Sandy Soil
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144
Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes
Published 2018“…Treating differentiated adipocytes with PBA did not alter their differentiation status, but decreased the leptin to adiponectin ratio. Conclusion: this study showed that PBA enhances adipocyte glucose uptake potentially through its effect on glucose transporter expression and/or trafficking via the PI3K signaling pathway; suggesting PBA as a possible candidate for the ancillary management of diabetes.…”
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Colloid retention and mobilization mechanisms under different physicochemical conditions in porous media: A micromodel study
Published 2021“…However, for hydrophobic colloids, changes in solution chemistry significantly increase colloid retention where the colloid interaction become attractive with the increase in ionic strength and decrease in pH values. …”
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Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
Published 2024“…It thereby poses a major challenge to proteostasis and activates UPR sensors. Pharmacological decrease of MG with Glo1 inducer, trans-resveratrol and hesperetin in combination, offers a novel treatment strategy to counter UPR-related cell dysfunction, particularly in hyperglycemia associated with diabetes.…”
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The Effects of New Public Management on Managers’ Work-Life Balance and Behavior
Published 2020“…It was found that the public sector has shifted its framework towards greater customer satisfaction, which has led to an increase in the workload of the managers. …”
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Performance of Different Concrete Types Exposed to Elevated Temperatures: A Review
Published 2022“…Heating rate, days of curing, type of curing, cooling method, and constituents of the mix are some of the factors that impact the post-fire behavior of concrete structures. …”
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153
Metformin inhibits 2D and 3D motility in astrocytoma cancer cells. (c2014)
Published 2016“…When this drug is applied, it led to a relative decrease in the proliferation of astrocytoma cancer cells. …”
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154
DIGITAL TRANSFORMATION AND THE CYBERSECURITY OF INFRASTRUCTURE SYSTEMS IN THE OIL AND GAS SECTOR
Published 2020“…With the twenty-first century called the golden age of digital transformation in the oil and gas sector, the increased connectivity of cyber-physical systems (CPSs) will generate new opportunities for organisations such as greater safety, reliability, and efficiency.…”
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Effects of natural organic matter on aggregation kinetics of boron nanoparticles in monovalent and divalent electrolytes
Published 2010“…However, the attachment efficiency kept increasing in the presence of CaCl2 and alginate with the increase in the electrolyte concentration and was greater than unity at >4 mM CaCl2. …”
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A customised fetal growth and birthweight standard for Qatar: a population-based cohort study
Published 2024“…The main pathological factors were preexisting diabetes (increase by +175.7 g) and smoking (decrease by −190.9 g). …”
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Metformin treatment inhibits motility and invasion of glioblastoma cancer cells
Published 2018“…Metformin, a commonly used drug for the treatment of diabetes, has recently emerged as a promising anticancer molecule. …”
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The Role of KM in Enhancing AI Algorithms and Systems
Published 2020“…However, studies were focusing on specific methods and the impact on some AI algorithms, neglecting the role of other KM processes and how it may affect the AI system to achieve the objective, which reduces the adoption in some organizations. …”
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What drives cryptocurrency pump and dump schemes: Coin versus market factors?
Published 2024“…These include lower market capitalization, lower trading volume, greater social media popularity, increased developer activity, and fewer exchanges trading them. …”
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