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481
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
منشور في 2023"…Finally, as a definitive and specific way to modulate SLFN11 expression we implemented SLFN11 dCas9 (dead CRISPR associated protein 9) systems to specifically increase or decrease SLFN11 expression.</p><h3>Results</h3><p dir="ltr">After confirming the previously reported correlation between methylation of SLFN11 promoter and its expression across multiple cell lines, we showed in-vitro that decitabine and IFN-γ could increase moderately the expression of SLFN11 in both BT-549 and T47D cell lines. …"
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482
TCAD Simulation and Analysis of Selective Buried Oxide MOSFET Dynamic Power
منشور في 2019"…The simulated fabrication of the three devices was conducted using Silvaco TCAD tools in 90 nm complementary metal oxide semiconductor (CMOS) technology. …"
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article -
483
Assessing Struvite Formation Potential at Wastewater Treatment Plants
منشور في 2012"…The three locations investigated all has a supersaturation value greater than unity; this indicated that struvite formation potential was high. …"
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article -
484
Mixed siliciclastic-carbonate-evaporite sedimentation in an arid eolian landscape: The Khor Al Adaid tide-dominated coastal embayment, Qatar
منشور في 2020"…These offshore-migrating eolian-derived sediments are being redistributed by tidal currents in an otherwise low-energy coastal zone, where in situ formation of carbonate mud and a low-diversity skeletal assemblage is ongoing within salinity-restricted environments. Three depositional sectors are delineated: 1) an energetic, linear, fault-controlled Entrance Channel into which the eolian dunes spill directly; 2) a relatively deep (up to 20 m) Outer Lagoon, interpreted to represent a flooded karst-collapse structure; and 3) a sprawling, low-energy, shallow (<2 m) Inner Lagoon occupying low-lying areas between deflated eolian dunes.Physical oceanographic modeling, integrating multi-seasonal current meter and tidal gage measurements, demonstrates tidal current flow velocities are relatively high in both the Entrance Channel and at the constricted entrance to the Inner Lagoon. …"
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article -
485
Modulation of gut microbiota: The effects of a fruits and vegetables supplement
منشور في 2022"…The antioxidant capacity, measured by using the oxygen radical absorbance capacity (ORAC) method, was also slightly higher in the FVS group than in the PLA group but did not reach statistical significance. The dietary intake, assessed by 24-h recalls, did not show any significant changes after the supplementation in both the groups. …"
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486
Bevacizumab and neovascular age related macular degeneration
منشور في 2011"…The mean number of letters gained, decrease in CRT, and number of injections were 8 letters, 125.3 µm, and 4.3 injections, respectively. …"
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article -
487
Anterior ankle impingment syndrome is less frequent, but associated with a longer absence and higher re-injury rate compared to posterior syndrome: a prospective cohort study of 67...
منشور في 2022"…AAIS and PAIS were similar regarding injury characteristics except for a greater proportion of AAIS having a gradual onset (69% vs.47%; P = 0.03) and being re-injuries (31% vs. 9%; P = 0.01). …"
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488
Storage allocation for diverse FPGA memory specifications
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conferenceObject -
489
Violent Extremism Prevention in the Era of Globalization
منشور في 2020"…The significance of the study stems from the fact that global strategizing efforts are needed to pay greater emphasis on the media and finance, specifically in weak and vulnerable states. …"
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masterThesis -
490
Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. …"
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491
Redox Homeostasis and Inflammation Responses to Training in Adolescent Athletes: a Systematic Review and Meta-analysis
منشور في 2020"…From those articles, 27 were included in the quantitative analysis (meta-analysis) as their results could be converted into common units.</p><h3>Results</h3><p dir="ltr">Following a short training session or performance test, an extremely large increase in protein carbonyls (PC) (ES 4.164; 95% CI 1.716 to 6.613;Z= 3.333,<i>p</i>= 0.001), a large increase in thiobarbituric acid reactive substances (TBARS) (ES 1.317; 95% CI 0.522 to 2.112;<i>Z</i>= 3.247,<i>p</i>= 0.001), a large decrease in glutathione (GSH) (ES − 1.701; 95% CI − 2.698 to − 0.705;<i>Z</i>= − 3.347,<i>p</i>= 0.001), and a moderate increase of total antioxidant capacity (TAC) level (ES 1.057; 95% CI − 0.044 to 2.158;<i>Z</i>= 1.882, <i>p</i>= 0.060) were observed. …"
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492
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493
The impact of maternal care on child development
منشور في 2019"…Results show that treated children enjoy an increase of 3.6 h per week in the time they spend with their mothers, mainly due to a decrease in the time spent in non-institutional care. …"
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article -
494
Characterization of Contusive Spinal Cord Injury by Monitoring Motor-Evoked Potential
منشور في 2024"…Methods: The methods section describes the experimental setup, including randomly assigned rats in three groups: Sham, Control, and Injury (undergoing a moderate contusive SCI using the NYU-Impactor). …"
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article -
495
Barriers facing self-employed women. (c2007)
منشور في 2007احصل على النص الكامل
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masterThesis -
496
Earthcasting: Geomorphic Forecasts for Society
منشور في 2021"…The importance of geomorphic forecasts has never been greater, as technological development and global climate change threaten to reshape the landscapes that support human societies and natural ecosystems. …"
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497
The antioxidant and anticancer effects of Wild Carrot oil extract
منشور في 2012"…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
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article -
498
Congenital melanocytic nevi
منشور في 2005"…Giant congenital melanocytic nevi are associated with an increased risk of the development of melanoma. On the other hand, there is evidence of an increased melanoma risk in patients with small congenital nevi. …"
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article -
499
Hybrid effect of carbon nanotubes and polypropylene microfibers on fire resistance, thermal characteristics and microstructure of cementitious composites
منشور في 2020"…The improvement was less significant in the case of exposure temperatures greater than melting point of the fibers. Thermal conductivity of cement mortar is increased by the addition of the CNTs but not the PP fibers for all heating levels. …"
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article -
500
Sustainable Concrete Mix Design: Experimental Study of Life-Size Columns
منشور في 2025"…This study addresses the use of a unique 3-part substation made from those materials, as well as the life-sizing of Sustainable mixes, which is not highlighted in previous research. …"
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masterThesis