In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation by Sleiman, Sama F.

“…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …”
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The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global... by Farin Kamangar (63964)

“…Oesophageal cancer caused 9·78 million (9·53–10·03) DALYs, with an age-standardised rate of 120 (117–123) per 100 000 population. Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …”

Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting by Tawa Olukade (11619453)

“…</p><h3>Results</h3><p dir="ltr">The mean maternal age was 29.7 ± 5.5 years, prepregnancy BMI was 27.5 ± 5.8 kg/m2, GWG was 9.58 kg ± 6.87 kg and gestational age at birth was 38.5 ± 1.9 weeks. In line with IOM recommendations, we found that higher BMI was correlated with decreased GWG and BMI was significantly associated with GWG even after adjusting for maternal age, parity, and infants’ gestational age at birth. …”

The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study by Richard Charles Franklin (9154052)

“…Global age-standardised mortality rates decreased 57.4%, from 9.3 (8.5 to 10.0) in 1990 to 4.0 (3.8 to 4.1) per 100 000 per annum in 2017. …”

CEO gender and managerial entrenchment by Dah, Mustafa A.

“…We find that the presence of female CEO decreases the turnover-performance sensitivity, increases the E-index, and inflates CEO compensation. …”
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Assessing Struvite Formation Potential at Wastewater Treatment Plants by Fattah, Kazi Parvez

“…The three locations investigated all has a supersaturation value greater than unity; this indicated that struvite formation potential was high. …”
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Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study by Brit Mollenhauer (482499)

“…Each of the four methods showed high analytical precision, excellent correlation between laboratories (R2 0.83–0.99), and good correlation with each other (R2 0.64–0.93), although the slopes of the regression lines were different between the four immunoassays. …”

The effect of StarD13 on colorectal cancer proliferation and invasion. (c2013) by Nasrallah, Anita I.

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Anterior ankle impingment syndrome is less frequent, but associated with a longer absence and higher re-injury rate compared to posterior syndrome: a prospective cohort study of 67... by Pieter D’Hooghe (3530984)

“…AAIS and PAIS were similar regarding injury characteristics except for a greater proportion of AAIS having a gradual onset (69% vs.47%; P = 0.03) and being re-injuries (31% vs. 9%; P = 0.01). …”

Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer by Sampath, Lakshmi

“…The tumor-to-muscle ratio decreased in mice pretreated with trastuzumab and in mice injected with IRDye 800CW and (111In-DTPA)p-IgG-(IRDye800)q. …”
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Violent Extremism Prevention in the Era of Globalization by Safieddine, Line Abbas

“…The significance of the study stems from the fact that global strategizing efforts are needed to pay greater emphasis on the media and finance, specifically in weak and vulnerable states. …”
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STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration by Ayat S. Hammad (9592374)

“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca²⁺ entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”

COPE for adolescent Syrian refugees in Lebanon: a brief cognitive–behavioral skill-building intervention to improve quality of life and promote positive mental health by Doumit, Rita

“…Lebanon has the highest per-capita concentration of refugees worldwide. …”
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Post-materialistic values and entrepreneurial intention– the case of Saudi Arabia by Alammari, Khalid

“…An online survey returned 405 valid questionnaires, representing a 27 per cent response rate. The data were analysed using partial least structural equation modelling. …”
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Barriers facing self-employed women. (c2007) by Issa, Sendrella

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Earthcasting: Geomorphic Forecasts for Society by Tejedor, Alejandro

“…The importance of geomorphic forecasts has never been greater, as technological development and global climate change threaten to reshape the landscapes that support human societies and natural ecosystems. …”
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Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications by Tooba Yasin (19131382)

“…It was found that increasing ZiF-8 decreases the swelling in different media and increases degradation in PBS media. …”

Congenital melanocytic nevi by Tannous, Zeina S.

“…Giant congenital melanocytic nevi are associated with an increased risk of the development of melanoma. On the other hand, there is evidence of an increased melanoma risk in patients with small congenital nevi. …”
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Hybrid effect of carbon nanotubes and polypropylene microfibers on fire resistance, thermal characteristics and microstructure of cementitious composites by Mohammad R., Irshidat

“…The improvement was less significant in the case of exposure temperatures greater than melting point of the fibers. Thermal conductivity of cement mortar is increased by the addition of the CNTs but not the PP fibers for all heating levels. …”
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An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat... by Merheb, Caroline

“…Even the addition of organic matter was not shown to be advantageous as the large pores found in RT were further decreased by the deposition of the organics. Notwithstanding, the role of organics was consistent in improving the water conductivity. …”
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