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Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing
Published 2022“…</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …”
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282
Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th...
Published 2020“…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global crude prevalence of avoidable vision impairment and blindness in adults aged 50 years and older did not change between 2010 and 2019 (percentage change −0·2% [95% UI −1·5 to 1·0]; 2019 prevalence 9·58 cases per 1000 people [95% IU 8·51 to 10·8], 2010 prevalence 96·0 cases per 1000 people [86·0 to 107·0]). …”
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283
RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells
Published 2019“…While knocking down either RHO, GTPase did not affect p-AKT levels, and p-ERK decreased in response to the knocking down of RHOG, CDC42 or RAC1. …”
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284
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
Published 2025“…While video evaluations did not detect significant changes, EMG data provided measurable differences in skill acquisition, suggesting that wearable sensors could enhance objective evaluations of surgical proficiency in residency programs.…”
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285
The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity
Published 2024“…Our findings indicate that an increased representation of women on the board of directors is associated with greater independence among board members and a higher number of board members being hired. …”
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286
Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study
Published 2023“…</p><h3>Conclusions</h3><p dir="ltr">This study found that patients who received a drain had longer hospital stays and greater blood loss and transfusion rates compared to those who did not. …”
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287
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
Published 2020“…</p> <h2>Results</h2> <p>A total of 4040 patients with fall-related injuries were identified in the study duration which corresponds to the rate of 2.34 per 10,000 population. Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …”
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288
The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
Published 2023“…Europe‘s aging population is increasing, affecting various sectors, including the healthcare system, labor market, and public services. …”
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289
Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases
Published 2005“…Adverse preoperative biologic factors including tumor number greater than 3 (P = 0.01) and a preoperative CEA level greater than 200 ng/mL (P = 0.04) were associated with an increased risk of positive surgical margin. …”
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290
MRP4
Published 2011“…Application of ISO (1nM) induced a similar increase in cAMP level in WT and MRP4 KO mice (YFP/CFP: 4.4 ± 0.15 in WT vs 4.1 ± 0.44 in KO cells), whereas cAMP signal was greater in MRP4 KO compared to WT mice after PDE inhibition by IBMX (ISO 1nM + IBMX 300µM: 8.1 ± 0.6 in WT vs 11.8 ± 0.62 in KO cells; p<0.01). …”
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Integration of Smart Sensors in Buildings to achieve Energy Efficiency in Hot and Humid Climate
Published 2021“…It is also estimated that this utilization would grow to above 50% by 2030 because of the fast and consistent growth in economic activity and increase in population around the world. People tend to spend the greater part of their time in indoor spaces e.g., commercial and residential buildings. …”
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293
Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat
Published 2023“…The samples with <i>F</i>. tataricum demonstrated greater amounts of fiber and ash while the samples made of soft wheat flour were rich in carbohydrates. …”
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294
Knee Angle Affects Posterior Chain Muscle Activation During an Isometric Test Used in Soccer Players
Published 2019“…These differences (30% mean difference) were greater than the observed typical measurement error (CV% = 13.1–14.3 for the 90° and 30° test positions, respectively). …”
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295
Optimization of Vapor Compression Refrigeration Cycles with Clathrate Hydrates Thermal Energy Storage
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296
The role of objectively recorded smartphone usage and personality traits in sleep quality
Published 2023“…<h3>Purpose</h3><p dir="ltr">The proliferation of smartphones, accompanied by internet facilities, has contributed to a decrease in sleep quality over the last decades. It has been revealed that excessive internet usage impacts the physical and mental health of smartphone users, while personality traits (PT) could play a role in developing internet addictions and preventing their negative effects. …”
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297
Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
Published 2019“…Exercise improved VO2 max (p < 0.01) but did not alter weight. Amino acid profiles were unaffected by an acute increase in IR induced by the lipid infusion. …”
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298
Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer
Published 2024“…Higher densities of stromal CD3<sup>+</sup>FoxP3<sup>+</sup> T cells showed enhanced survival outcomes, and patients exhibited superior clinical benefits when greater spatial distances were observed between CD3<sup>+</sup>CD8<sup>-</sup>FoxP3<sup>-</sup> or CD3<sup>+</sup>CD8<sup>+</sup> T cells and CD3<sup>+</sup>FoxP3<sup>+</sup> T cells.…”
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Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study
Published 2023“…Moreover, homozygous variants were found in 7 families (25.9%), with a sixfold increase in homozygous burden in consanguineous versus non-consanguineous families (13.6% and 1.8%, respectively). …”
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