Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shehaby, Wassim N.

“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …”
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The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery – A Follow-Up Study... by Nasser M Rizk (18810328)

“…The study aimed to follow up on the changes in the peripheral CD4+ T lymphocytes and the pro-inflammatory cytokines; IL-6, TNF-alpha, MCP-1, and IL-10 at baseline and 12 weeks post-surgical intervention by the laparoscopic gastric sleeve (LGS) in morbidly obese patients (class III obesity subjects). </p><h3>Materials and Methods </h3><p dir="ltr">A prospective longitudinal research included 24 class III obesity subjects with a BMI > 40 kg/m². …”

Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation by Salman, Zeina

“…Functional assays revealed that miR-222-5p overexpression led to a significant increased expression of key pro-inflammatory cytokines, including IL-8 and TNF-α, while knockdown of these miRNAs resulted in their decreased expression. Western blot and pathway analyses demonstrated that miR-222-5p and miR-21-3p overexpression increased phosphorylation of p65, a key component of the NF-κB complex, while their knockdown reduced p65 phosphorylation. …”
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Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts by Amr A. Fadle (14150298)

“…The mean time to union in the double and triple arthrodesis groups was 3.39 ± 0.65 vs. 3.31 ± 0.6 months, respectively, with no statistically significant differences (p = 0.77). …”

Stability enhancement of Al₂O₃, ZnO, and TiO₂ binary nanofluids for heat transfer applications by Ans Ahmed Memon (21633692)

“…X-ray diffraction and zeta potential were performed to characterize three nanoparticles, namely TiO₂, Al₂O₃, and ZnO. …”

Effect of Mg incorporation on the properties of PCL/Mg composites for potential tissue engineering applications by Sumama Nuthana Kalva (19206064)

“…This study investigates the influence of Mg incorporation on the properties of PCL/Mg composites, aiming to evaluate their suitability for 3D-printable (3DP) tissue engineering applications. …”

A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor by Anupriya M. Geethakumari (17052375)

“…Co-expression of the sensors with M^pro in live cells resulted in their cleavage while mutation of the critical C145 residue (C145A) in M^pro completely abrogated their cleavage. …”

A new insight into the separation of oil from oil/water emulsion by Fe₃O₄–SiO₂ nanoparticles by Wamda Faisal Elmobarak (17058024)

“…For the oil recovery process, the Fe₃O₄ was applied for the inhibition (i.e., decrease) of oil sedimentation, and the SiO₂ NPs were applied for wettability alteration and IFT reduction. …”

Application of Fe₃O₄ magnetite nanoparticles grafted in silica (SiO₂) for oil recovery from oil in water emulsions by Wamda Faisal Elmobarak (17058024)

“…Using an MD_dose as low as 10 mg/L attained a %_hdem in the range of 93% - 4.3% for O/W mixtures with C_oil < 2000 mg/L, which slightly decreased to ~90% for higher concentrations. …”

Reactions, Adsorption and Diffusion in FCC Catalysts by Mahaly, Wafa

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Removal of Benzene and Toluene from Synthetic Wastewater by Adsorption onto Magnetic Zeolitic Imidazole Framework Nanocomposites by George Z. Kyzas (740387)

“…Thus, by performing the present study, the potential of Fe₃O₄/zeolite imidazolate framework nanoparticles (Fe₃O₄@ZIF-8) was evaluated for the adsorption of benzene and toluene. …”

Comparing WZB117-liposome Synthesis via Thin-film Hydration and Microfluidic Methods by Yaramiree, Atena

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Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch by Zhang, Wenhao

“…After fluorescence-activated cell sorting, VAMP7 knockout basophils exhibited reduced activity, with OSM downregulated in AIF and CCR3 reduced in both models. VAMP7 knockout also decreased IL-4 and LTC4 release from basophils. …”
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Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... by Katherine R Paulson (8674293)

“…The first metric is a global optimum and is based on the lowest observed mortality, and the second is a survival potential frontier that is based on stochastic frontier analysis of observed mortality and Healthcare Access and Quality Index.</p><p><br></p><h3>Findings</h3><p dir="ltr">Global U5MR decreased from 71·2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68·3–74·0) in 2000 to 37·1 (33·2–41·7) in 2019 while global NMR correspondingly declined more slowly from 28·0 deaths per 1000 live births (26·8–29·5) in 2000 to 17·9 (16·3–19·8) in 2019. …”

The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20... by Sudabeh Alatab (11257335)

“…Findings In 2017, there were 6·8 million (95% UI 6·4–7·3) cases of IBD globally. The age-standardised prevalence rate increased from 79·5 (75·9–83·5) per 100 000 population in 1990 to 84·3 (79·2–89·9) per 100 000 population in 2017. …”

Enhanced optical properties of <i>β</i>-Ga₂O₃-_<em>x</em>S_<em>x</em>S: A DFT study by G.B. Eshonqulov (22927297)

“…Here, we conduct systematic density functional theory calculations to study the effect of sulfur doping on the electronic and optical properties of <i>β</i>-Ga₂O₃. We find that the band gap of the material decreases with increasing sulfur content (from 4.81 eV to 1.59 eV), accompanied by symmetric shifts in both the valence-band offset and the conduction-band edge. …”

Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches by Roba Shady (22048043)

“…At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”

Women’s empowerment as a determinant of neonatal mortality in Sub-Saharan Africa: a narrative review focused on Nigeria by Joel-Medewase Victor Idowu (22155178)

“…Notably, SSA and South Asia are the regions most lagging behind the Sustainable Development Goal (SDG) 3.2, aiming for <12 neonatal deaths per 1,000 live births by 2030. …”

Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content by Haissam Abou-Saleh (497840)

Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar by Dina Abushanab (10696501)

“…The total economic benefit of the ASP maturity was calculated as the sum of the cost savings and the cost avoidance associated with the service minus the operational cost.3 Cost savings were the reduction in therapy cost linked to decreased antimicrobial consumption and resource utilization. …”