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Decreased phosphodiesterase activities in cardiac hypertrophy
Published 2007“…In S myocytes, PDE3 inhibition had no effect on ICa,L time-course, whereas PDE4 inhibition prolonged the signal. …”
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Assessment of community noise problem in greater Beirut area, Lebanon
Published 2003“…Over the last two decades, urban noise has been increasingrapidly, primarily in urban areas, due to population growthand the increase of certain noise sources. The main objectiveof this paper is to assess the sources and possible impactsof the community noise problems in Lebanese urban areas,particularly the Greater Beirut Area. …”
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The effect of vancomycin doses greater than 2 grams on serum creatinine and vancomycin trough levels
Published 2014“…Conclusion: The use of doses greater than 2 grams of IV vancomycin did not show a statistically significant increase in serum creatinine. …”
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Determinants of improper versus proper waste disposal practices by households: Evidence from greater Cairo’s urban slums
Published 2025“…Accordingly, this study investigates the determinants of household solid waste disposal practices in the urban slums of Greater Cairo using data from the Survey of Young People in Informal Urban Areas of Greater Cairo (SYPE-IGC) in 2016. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …”
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Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals
Published 2009“…Methods and Results: Cardiac hypertrophy was induced in rats by thoracic aortic banding over a time period of 5 weeks and was confirmed by anatomic measurements and echocardiography. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Effective non-intrusive load monitoring of buildings based on a novel multi-descriptor fusion with dimensionality reduction
Published 2020“…The latter can not only reduce feature dimensionality, but it can also effectively decrease the intra-class distances and increase the extra-class distances of appliance features; and (iii) a powerful decision bagging tree classifier is implemented to accurately classify electrical devices using the reduced features. …”
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Timing driven genetic placement
Published 2020“…IN this paper we present a timing driven placer for standard cell IC design. …”
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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
Published 2024“…The slightest increase in LST was within forested areas as the average LST increased from 28.42 °C in 1980 to 34.16 °C in 2023. …”
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Effect of Anthrax Lethal Toxin on Activation of MAPK Pathway and Autophagy in AML Cell Lines
Published 2021“…Flow cytometry analysis of downstream effectors of MEK showed decrease in phosphorylation of ERK and its downstream effectors only at early time points in sensitive cell lines. …”
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The antiproliferative and pro-apoptotic effect of kefir on human leukemic cell lines. (c2008)
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Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
Published 2016“…Similarly, the droplet size of Intralipid increased from 283.3 to 294.6nm on inclusion of 6mg/ml paclitaxel. …”
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Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines
Published 2022“…Monotherapy with CBD demonstrated a dose-dependent tumor growth inhibition at 72h, with the IC50 being 12.5 μg/ml for OVCAR-3 cell line and 12.3 μg/ml for SK-OV-3 cell line. The IC50 of cisplatin against OVCAR-3 and SK-OV-3 cell lines (1.1 and 3.3 μg/ml, respectively), and that of paclitaxel against SK-OV-3 cell line (9.9 μg/ml) were obtained as well. …”
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