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481
3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations
Published 2022“…<p dir="ltr">Despite the efforts devoted to drug discovery and development, the number of new drug approvals have been decreasing. Specifically, cardiovascular developments have been showing amongst the lowest levels of approvals. …”
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482
Prevalence of bullying and violence among adolescents in Arab Gulf countries: a systematic review
Published 2025“…The findings underscore the urgent need for tailored assessment approaches, gender-responsive interventions, integrated school-based mental health services, and culturally focused prevention strategies that address both traditional and cyberbullying in the rapidly evolving sociocultural context of the AGC.…”
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483
Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish
Published 2019“…While clinical echocardiography platforms can be used for relatively large animals such as pigs and rats, specialized systems are needed for smaller species. Theoretically, as the size of the imaged sample decreases, the frequency of the ultrasound transducer needed to image the sample increases. …”
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484
Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease St...
Published 2025“…From 2022 to 2050, global increases in overweight (not obesity) prevalence are forecasted to stabilise, yet the increase in the absolute proportion of the global population with obesity is forecasted to be greater than between 1990 and 2021, with substantial increases forecast between 2022 and 2030, which continue between 2031 and 2050. …”
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485
Recovery of business intelligence systems
Published 2018“…Any denial of this service will not be tolerated since we cannot know when we need to retrieve a patient’s record. Denial of service affects the continuity of the healthcare system which in turn threatens patients’ lives, decreases the efficiency of the healthcare system and increases the operating costs of the attacked healthcare organization. …”
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486
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008“…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …”
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conferenceObject -
487
An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH<sub>4</sub>-CO<sub>2</sub>-H<sub>2</sub>S
Published 2021“…Consequently, this model eliminates difficulties associated with the need for experiments on ternary system solid-fluid phase equilibria.…”
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488
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Published 2021“…Therefore, blood banks in Qatar might need to consider screening for B19V, especially when transfusion is intended for high-risk populations, including immunocompromised patients.…”
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489
A Scoping Review to Find Out Worldwide COVID-19 Vaccine Hesitancy and Its Underlying Determinants
Published 2021“…Therefore, strategies tailored to cultures and socio-psychological factors need to be developed to reduce vaccine hesitancy and aid informed decision-making.…”
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490
Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study
Published 2025“…These findings highlight the need for individualized IV iron therapy as a first-line treatment in young healthy patients to improve outcomes and optimize healthcare resources.…”
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491
Business Continuity Management Maturity Model for Banks in UAE
Published 2008“…Methods as security and disaster recovery are no longer enough to fulfill the continuity needs of the organization. Also, there is increasing pressure that is forcing organizations to take measures to assure the continuity of their business. …”
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492
Essays on international environmental policy
Published 2009“…With the growing talk about the need to establish a new framework to deal with international environmental governance, it becomes relevant to shed some light on the interconnected landscape that characterizes environmental policy making. …”
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493
Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response
Published 2019“…These observations support the need to consider anti-NRP-1 as a potential targeted therapy for breast cancer patients who are identified with high NRP-1 levels. …”
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494
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
Published 2021“…<h3>Background</h3><p dir="ltr">Parkinson’s disease is a disabling neurodegenerative movement disorder characterized by dopaminergic neuron loss induced by α-synuclein oligomers. There is an urgent need for disease-modifying therapies for Parkinson’s disease, but drug discovery is challenged by lack of in vivo models that recapitulate early stages of neurodegeneration. …”
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495
An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat...
Published 2022“…Nevertheless, implementing all management systems to determine water infiltration capacities for a specific site can be costly and time-consuming. Hence, the need for a mathematical model that computes infiltration into agricultural soils is necessary. …”
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masterThesis -
496
Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis
Published 2022“…Female sex (61.5 % vs. 41.3 %, p = 0.019), hypoxemia (90 % vs. 59.2 %, p < 0.001), massive PE features (89.7 % vs. 30.1 %, p < 0.001), associated chronic kidney disease (CKD) (10.3 % vs. 1.4 %, p = 0.002), and the need for mechanical ventilation (28.2 % vs. 13.1 %, p = 0.02) were significantly associated with increased mortality. …”
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497
Mitigating the impact of cultural diversity on the innovation process in the private sector in Dubai
Published 2017“…The author further noted that cultural diversity has formed a paramount issue in business arena that need to be investigated to pave a clear way in order to accommodate people from various backgrounds. …”
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498
Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17
Published 2020“…Interpretation Our estimates, combined with geospatial trends in diarrhoeal burden, identify where efforts to increase access to safe drinking water and sanitation facilities are most needed. By highlighting areas with successful approaches or in need of targeted interventions, our estimates can enable precision public health to effectively progress towards universal access to safe water and sanitation. …”
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499
Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Addressing inequities in universal maternal health coverage, strengthening the quality of maternal health care, and improving the robustness of data systems are urgently needed to reduce the global burden of stillbirths. …”
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500
Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1
Published 2021“…Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. …”