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Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration
Published 2009“…Studies of ABCB1 and ABCG2 activity showed that MPTP intoxication did not alter their functionality. Conversely, ABCG2 expression studied on brain capillaries from MPTP-treated mice was decreased (1.3-fold, p<0.05) and ABCB1 expression increased (1.43-fold, p<0.05) as an off-setting of brain transport. …”
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Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma
Published 2004“…The presence of hepatitis did not significantly affect the survival rate, but hepatic fibrosis and vascular invasion predicted a decreased survival rate. …”
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Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis
Published 2021“…</p><h3>Conclusions</h3><p dir="ltr">The challenges and concerns that impede the use of Patient Online seem to be of greater importance than the facilitators that encourage its use. …”
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Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing
Published 2022“…</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …”
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RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells
Published 2019“…While knocking down either RHO, GTPase did not affect p-AKT levels, and p-ERK decreased in response to the knocking down of RHOG, CDC42 or RAC1. …”
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Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
Published 2025“…While video evaluations did not detect significant changes, EMG data provided measurable differences in skill acquisition, suggesting that wearable sensors could enhance objective evaluations of surgical proficiency in residency programs.…”
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307
The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity
Published 2024“…Our findings indicate that an increased representation of women on the board of directors is associated with greater independence among board members and a higher number of board members being hired. …”
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Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study
Published 2023“…</p><h3>Conclusions</h3><p dir="ltr">This study found that patients who received a drain had longer hospital stays and greater blood loss and transfusion rates compared to those who did not. …”
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Studies on Natural Extracts as Inhibitors of Mild Steel Corrosion in 1M HC1 Solution
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Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases
Published 2005“…Adverse preoperative biologic factors including tumor number greater than 3 (P = 0.01) and a preoperative CEA level greater than 200 ng/mL (P = 0.04) were associated with an increased risk of positive surgical margin. …”
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MRP4
Published 2011“…Application of ISO (1nM) induced a similar increase in cAMP level in WT and MRP4 KO mice (YFP/CFP: 4.4 ± 0.15 in WT vs 4.1 ± 0.44 in KO cells), whereas cAMP signal was greater in MRP4 KO compared to WT mice after PDE inhibition by IBMX (ISO 1nM + IBMX 300µM: 8.1 ± 0.6 in WT vs 11.8 ± 0.62 in KO cells; p<0.01). …”
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Integration of Smart Sensors in Buildings to achieve Energy Efficiency in Hot and Humid Climate
Published 2021“…It is also estimated that this utilization would grow to above 50% by 2030 because of the fast and consistent growth in economic activity and increase in population around the world. People tend to spend the greater part of their time in indoor spaces e.g., commercial and residential buildings. …”
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Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat
Published 2023“…The samples with <i>F</i>. tataricum demonstrated greater amounts of fiber and ash while the samples made of soft wheat flour were rich in carbohydrates. …”
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317
Knee Angle Affects Posterior Chain Muscle Activation During an Isometric Test Used in Soccer Players
Published 2019“…These differences (30% mean difference) were greater than the observed typical measurement error (CV% = 13.1–14.3 for the 90° and 30° test positions, respectively). …”
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Intravitreal adalimumab in active noninfectious uveitis
Published 2016“…One patient (1 eye) failed treatment. Seven out of 12 eyes had improvement of ≥2 ETDRS lines. …”
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Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
Published 2019“…Exercise improved VO2 max (p < 0.01) but did not alter weight. Amino acid profiles were unaffected by an acute increase in IR induced by the lipid infusion. …”
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