The immune landscape of solid pediatric tumors by Shimaa Sherif (12862990)

“…<h3>Background</h3><p dir="ltr">Large immunogenomic analyses have demonstrated the prognostic role of the functional orientation of the tumor microenvironment in adult solid tumors, this variable has been poorly explored in the pediatric counterpart.…”

COVID-19 may have increased global support for universal health coverage: multi-country observational study by Claudia F. Nisa (11346055)

“…</p><h3 dir="ltr">Conclusion</h3><p dir="ltr">The COVID-19 pandemic may have been a potential turning point in the global public support for UHC, as evidenced by a higher level of consensus that governments should be guarantors of healthcare.…”

Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials by Yara Wanas (8744844)

“…<h3>Background</h3><p dir="ltr">Angiotensin receptor blockers (ARBs) are commonly used as a treatment for many cardiovascular diseases, but their safety has been called into question. The VALUE trial found an increased risk of myocardial infarction in participants receiving ARBs compared to other antihypertensive. …”

Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish by Fatiha M. Benslimane (6695087)

“…In the last few decades, echocardiography has been applied to <i>in vivo</i> cardiac disease models, mainly to rodents. …”

Strain rate effect on twip/trip high entropy alloy by El Batal, Omar Mohammad Marwan

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Effect of Flexural NSM-FRP Bars on the Shear Strength of Reinforced Concrete Beams by Saleh, Rayyan Bashar

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Optimization of Vapor Compression Refrigeration Cycles with Clathrate Hydrates Thermal Energy Storage by Gadalla, Akram Mohamed

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The effect of indoor air quality on health and performance of labors in joinery factories by Sadeghi, Hengameh

“…The growing population and the rising number of investors have a huge impact on the construction industry, and the demand for joinery items will increase. Wood has been well known for thousands of years as one of the first few natural renewable resources in the world (Rastogi et al. 1989). …”
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ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder by Sara Cuvertino (18892069)

“…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …”

Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications by Fang Yu (156838)

“…Given its central role in immune cell activation, SOCE has been a therapeutic target for autoimmune and inflammatory diseases. …”

Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity by Abu Saleh Md Moin (6189512)

“…<h3>Objective</h3><p dir="ltr">Detailed proteomic analysis in a cohort of patients with differing severity of COVID-19 disease identified biomarkers within the complement and coagulation cascades as biomarkers for disease severity has been reported; however, it is unclear if these proteins differ sufficiently from other conditions to be considered as biomarkers.…”

Immunoprofile of childhood diabetes by Meritxell Espino-Guarch (15430868)

“…Associated with these findings, anti-inflammatory Treg cytokines including IL-10 were decreased in T2D patients and elevated plasma levels of IL-17, which contributes to the insulin resistance and inflammation were observed.…”

Responding to Students' Writing in UAE Government Secondary Schools: Teachers' Attitudes and Practices, and Students' Perceptions by Abou Eissa, Aida Fares

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Business Continuity Management Maturity Model for Banks in UAE by Mahal, Ashish

“…Realizing that these electronic systems have been, the major factor distinguishing competitors in today’s demanding business environment, organizations are taking steps to protect themselves from system failures. …”
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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes by Shadi Nejat (19457212)

“…<p dir="ltr">Several pathways and/or genes have been shown to be dysregulated in obesity-induced insulin resistance (IR) and type 2 diabetes (T2D). …”

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

“…Prevalence of raised blood pressure decreased in high-income and some middle-income countries; it remained unchanged elsewhere. …”
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Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Joseph L Ward (9715619)

“…Annual percentage decrease in all-cause mortality rate since 1990 in adolescents aged 15–19 years was 1·3% in males and 1·6% in females, almost half that of males aged 1–4 years (2·4%), and around a third less than in females aged 1–4 years (2·5%). …”

Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer by Sampath, Lakshmi

“…Overexpression of the human epidermal growth factor receptor (HER) family has been implicated in cancer because of its participation in signaling pathways regulating cellular proliferation, differentiation, motility, and survival. …”
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…<p dir="ltr">Dysregulated epigenetic modifications are common in lung cancer but have been reversed using demethylating agent like 5-Aza-CdR. 5-Aza-CdR induces/upregulates the NY-ESO-1 antigen in lung cancer. …”

Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans by Kevin S. Chen (9201767)

“…Three of these compounds also decreased α-synuclein oligomers in mammalian neurons, including rifabutin which has not been previously investigated for Parkinson’s disease. …”