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441
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
Published 2022“…<p>Loss of function mutations in store-operated Ca<sup>2+</sup> entry (SOCE) are associated with severe paediatric disorders in humans, including combined immunodeficiency, anaemia, thrombocytopenia, anhidrosis and muscle hypotonia. Given its central role in immune cell activation, SOCE has been a therapeutic target for autoimmune and inflammatory diseases. …”
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442
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
Published 2022“…<p dir="ltr">Transport of fine particles in porous media has attracted a considerable interest over the past several decades given its importance to many industrial and natural processes. …”
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443
An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School
Published 2022“…This is despite the fact that both groups of students are native Arabic speakers, and that both groups of students attend Arabic classes that use the same curriculum and textbooks. Given the high number of British as well as other non-Arabic schools in Dubai, this is a significant issue as many Arabic-speaking students are failing to achieve proficiency in their native language. …”
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444
The effect of microbiome therapy on COVID-19-induced gut dysbiosis: A narrative and systematic review
Published 2024“…These interventions reduced mortality rates, decreased hospital stays, improved oxygen saturation levels, alleviated gastrointestinal symptoms, enhanced immune response, and improved cognition.…”
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445
Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
Published 2024“…<h3>Introduction</h3><p dir="ltr">Caloric restriction (CR) is a nutritional intervention that increases life expectancy while lowering the risk for cardio-metabolic disease. …”
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446
A Scoping Review to Find Out Worldwide COVID-19 Vaccine Hesitancy and Its Underlying Determinants
Published 2021“…<div><p>Background: The current crisis created by the coronavirus pandemic is impacting all facets of life. Coronavirus vaccines have been developed to prevent coronavirus infection and fight the pandemic. …”
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447
Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
Published 2025“…The review synthesized quantitative evidence (2000–2025) from techno-economic and life-cycle studies and pilot demonstrations covering wastewater integration, flue-gas CO<sub>2</sub> utilization, immobilized cultivation, hybrid ORP–PBR operation, and biorefinery co-products. …”
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448
Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
Published 2019“…<h3>Background: </h3><p dir="ltr">Early metabolic responses following bariatric surgery appear greater than expected given the initial weight loss and coincide with improvement in diabetes. …”
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449
The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar
Published 2023“…Our study aims to investigate the effect of metformin when given to women with GDM and additional risk factors for FGR like hypertension, inherited or acquired thrombophilia, anemia, and autoimmune disorders such as anti-phospholipid syndrome, lupus erythematosus.…”
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450
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451
Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2021“…</p><p><br></p><h3>Methods</h3><p dir="ltr">Based on the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 methodology, we evaluated the incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs) of respiratory tract cancers (ie, tracheal, bronchus, and lung cancer and larynx cancer). …”
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452
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…Many recent clinical and genetic studies have reported a series of CaM mutations in patients with life‐threatening arrhythmogenic syndromes, such as long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). …”
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453
Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study
Published 2021“…Participants experiencing higher levels of anxiety should be given more attention during reintegration and transitional phases in schools. …”
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454
Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease St...
Published 2025“…From 2022 to 2050, global increases in overweight (not obesity) prevalence are forecasted to stabilise, yet the increase in the absolute proportion of the global population with obesity is forecasted to be greater than between 1990 and 2021, with substantial increases forecast between 2022 and 2030, which continue between 2031 and 2050. …”
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455
Mitigating the impact of cultural diversity on the innovation process in the private sector in Dubai
Published 2017“…It is true that the aim of any business is to make profit, with decreased profit in the sector many entrepreneurs have discovered other investment schemes which has resulted to more demand of the workforce. …”
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456
Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
Published 2022“…Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). …”
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457
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2021“…</p><p><br></p><h3>Interpretation</h3><p dir="ltr">In the absence of intervention, the annual toll of 7·69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. …”
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458
Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021
Published 2023“…By 2050, 89 (43·6%) of 204 countries and territories will have an age-standardised rate greater than 10%. InterpretationDiabetes remains a substantial public health issue. …”
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459
Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050
Published 2024“…MethodsThe global prevalence, years lived with disabilities (YLDs), disability-adjusted life years (DALYs), projection, and inequality were estimated for early MSK diseases, including rheumatoid arthritis (RA), osteoarthritis (OA), low back pain (LBP), neck pain (NP), gout, and other MSK diseases (OMSKDs). …”
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460
The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global B...
Published 2019“…</p><p><br></p><h3>Methods</h3><p dir="ltr">Vital registration, sample vital registration, verbal autopsy, and cancer registry data were used to generate incidence, death, and disability-adjusted life-year (DALY) estimates of colorectal cancer at the global, regional, and national levels. …”