Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

"…Agonists of the glucagon-like peptide-1 receptor (GLP-1R), currently approved to treat type 2 diabetes, hold promise to improve steatosis and even steatohepatitis. …"

The Development of Metal-Free Porous Organic Polymers for Sustainable Carbon Dioxide Photoreduction حسب Bariki, Ranjit

"…A viable tactic to effectively address the climate crisis is the production of renewable fuels via photocatalytic reactions using solar energy and available resources like carbon dioxide (CO₂) and water. Organic polymer material-based photocatalytic materials are thought to be one way to convert solar energy into valuable chemicals and other solar fuels. …"
احصل على النص الكامل

Sustainability of Composite Columns under Repeated Load and Harsh Environment حسب Kashwani, Ghanim

احصل على النص الكامل

Protein and glucose metabolism in response to hyperinsulinemia with and without hyperaminoacidemia in men with type 2 diabetes mellitus حسب Bassil, Maya Said

"…The presence of insulin resistance of protein in T2DM men has important implications for dietary protein recommendations as it suggests their protein requirements may be greater than current DRIs. Further investigation is warranted to address this issue in women and whether other dietary interventions known to improve insulin resistance of glucose metabolism in T2DM would modulate that of protein metabolism.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties حسب Ovidiu, Ciobanu

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses حسب Merilyn Lock (9440240)

"…Meta-analyses included 19 studies for V̇ O_2max, eight for peak power output from V̇ O_2max testing (PPO), and five for threshold power (powerAT). …"

Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data حسب Majdoleen Alalawneh (13961580)

"…Within BMI categories, a similar increasing trend was observed in underweight, normal, and overweight patients, while from 2018 to 2020, there was a decreasing trend in rivaroxaban prescribing in all obese classes. …"

Application of Emotional Intelligence in Surgical Education: A Scoping Review حسب Arshad Ali (638656)

"…<h3>Background</h3><p dir="ltr">Emotional Intelligence (EI) encompasses the ability to perceive, understand, and manage emotions and is increasingly recognized as a vital nontechnical (soft) skill within surgical education. …"

Genomic Landscape And Structural Impact Of Biotinidase (BTD) Variants In A Middle Eastern Population حسب BalaSubramani Gattu Linga (19325617)

"…MD simulations indicated that H323R, D444H, and P497S exhibited greater structural flexibility (increased RMSD/RMSF and PCA trace values), whereas R209C and D444H demonstrated reduced compactness (higher radius of gyration). …"

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

"…Second, we examined symptom queries preceding queries on the 12-step program at time lags of 0-7 days, 7-14 days, and 14-30 days, where the probability of asking about a medical symptom was greater in the 30-day time window preceding 12-step program information-seeking as compared to all previous times that the symptom was queried.…"

Visible Light Photocatalytic Activity of Ag/WO₃ Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark حسب Maha Matalkeh (17148358)

"…HRTEM, XPS analysis shows that the photocatalyst has a large sheet-like morphology with well-dispersed small metallic Ag particles (<3 nm) on the WO₃ nanoparticle's surface, with most particles near the edges. …"

Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy حسب Olfa Khalifa (10914452)

"…<div><p>Non-alcoholic fatty liver disease (NAFLD) is a common liver lesion that is untreatable with medications. Glucagon-like peptide-1 receptor (GLP-1R) agonists have recently emerged as a potential NAFLD pharmacotherapy. …"

An efficient failure-resilient mutual exclusion algorithm for distributed systems leveraging a novel zero-message overlay structure حسب Mouna Rabhi (17086969)

"…<p>In this paper, we provide a novel failure-resilient token-based mutual exclusion (ME) algorithm for distributed systems. Like a few other solutions in the literature, the proposed solution leverages a logical tree as its underlying topology. …"

Evaluation of high-temperature reverse osmosis for recycling boiler blowdown in industrial applications حسب Joel Minier-Matar (17052378)

"…The membrane rejection decreased from 97 % at 35°C to 92 % at 60°C; due to the increase in the diffusivities of ions at higher temperatures; however, the permeate quality met the boilers feedwater specifications. …"

Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments حسب Gunjan Dagar (9339276)

"…CAR-T therapy has achieved FDA approval for treating blood cancers like B-cell acute lymphoblastic leukemia, large B-cell lymphoma, and multiple myeloma by targeting CD-19 and B-cell maturation antigens. …"

Zirconium Silicate/IL/Mxene-based composite membranes for high-temperature fuel cell applications حسب Edwin, Reeves Nayagam

احصل على النص الكامل

Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy حسب Palavecino, Martin

"…Despite these improvements, blood transfusion is still reported in more than one third of patients who undergo liver resection.4, 5, 6 and 7 These high rates of blood transfusion are likely associated with patient and tumor factors. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function حسب Muge Sarper (3855454)

"…Conversely, knock-down of MMP-8 in N-1089 reduced adhesion and increased migration. Expression of MMP-8 WT in β6-1089 led to greater localisation of α6β4 to HD and reduced retraction fibre formation, this being reversed by MMP-8 knock-down in N-1089. …"

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 حسب Joan B Soriano (6458528)

"…Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578–4 044 819) in 2017, an increase of 18·0% since 1990, while total DALYs increased by 13·3%. …"

Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... حسب Saeid Safiri (3713035)

"…Age-standardised death rate decreased by 15.7% (8.6 to 21.0), during the period 1990–2019. …"