Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors by Noura Aldous (15429873)

“…Furthermore, induced pluripotent stem cell (iPSC) lines lacking RFX6 were generated using CRISPR/Cas9. …”

Electrically conductive hybrid organic crystals as flexible optical waveguides by Li, Liang

“…In cyclic operation mode, their conductivity decreases less than 1% after 10,000 thermal cycles. …”
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Application of Emotional Intelligence in Surgical Education: A Scoping Review by Arshad Ali (638656)

“…<h3>Background</h3><p dir="ltr">Emotional Intelligence (EI) encompasses the ability to perceive, understand, and manage emotions and is increasingly recognized as a vital nontechnical (soft) skill within surgical education. …”

Genomic Landscape And Structural Impact Of Biotinidase (BTD) Variants In A Middle Eastern Population by BalaSubramani Gattu Linga (19325617)

“…MD simulations indicated that H323R, D444H, and P497S exhibited greater structural flexibility (increased RMSD/RMSF and PCA trace values), whereas R209C and D444H demonstrated reduced compactness (higher radius of gyration). …”

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis by George Nitzburg (18614989)

“…Second, we examined symptom queries preceding queries on the 12-step program at time lags of 0-7 days, 7-14 days, and 14-30 days, where the probability of asking about a medical symptom was greater in the 30-day time window preceding 12-step program information-seeking as compared to all previous times that the symptom was queried.…”

Towards Industry 4.0 and Sustainable Manufacturing Applying Environmentally Friendly Machining of a Precipitation Hardened Stainless Steel Using Hot Turning Process by Mohammadjafar Hadad (17541345)

“…Experimental and FEM analysis shows that cutting force reduction at a preheating temperature of 300 °C is one of the reasons that reduces tool wear compared to conventional turning. Moreover, it has been shown that by increasing preheating temperature in hot turning, the hardness of the carbides in the workpiece decreases more than the hardness of the tool substrate and reduces coating materials, consequently reducing cutting tool abrasion wear phenomenon.…”

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…This involvement of ROS is confirmed with the gradual increase in intracellular ROS levels, reaching a peak at 48 hours after treatment. This is followed by an increase in lipid peroxidation which peaks at later timepoints and varies between different cell lines. …”
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Corporate Governance and the diversification discount by Boumosleh, Anwar

“…However, we find that the sensitivity of the diversification discount to CEO power decreases significantly after the implementation of the Sarbanes-Oxley Act, which implies that the restrictions and regulations passed by the act enhance corporate governance and limit the misallocation of resources and the diversification discount respectively.…”
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Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response by Noura Al-Zeheimi (5177066)

“…To further identify the role of NRP-1 and its interacting molecules in correspondence with patients' response to neoadjuvant chemotherapy (NAC), we conducted a comparative study on blood and tissue samples collected from a cohort of locally advanced breast cancer patients, before and after neoadjuvant chemotherapy (NAC). From a panel of tested proteins and genes, we found that the levels of plasma NRP-1, placenta growth factor (PlGF) and immune cell expression of the transcription factor <i>SNAI1</i> before and after NAC were significantly different. …”

Positional and dimensional temporomandibular joint osseous changes in patients treated with the forsus fatigue resistant device: a non-randomized clinical trial by Ramy Abdul-Rahman Ishaq (22928974)

“…Participants were divided into a treatment and a control group. After alignment and leveling with fixed orthodontic appliances using 0.019 × 0.025-inch stainless-steel archwires, the FFRD was fitted. …”

Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth by Felipe, Torquato

“…A step further is now required to determine whether these platform foundations should be converted to reefs after their decommissioning (i.e., Rigs to Reefs approach).…”
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Finite-element solution of monopolar corona on bundle conductors by Al-Hamouz, Z.

“…The effect of the number of bundles, and the bundle spacing on the corona current and ground-plane current density profiles is investigated. It has been found that, with the increase in the number of bundles, the corona current decreases. …”
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Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function by Muge Sarper (3855454)

“…Conversely, knock-down of MMP-8 in N-1089 reduced adhesion and increased migration. Expression of MMP-8 WT in β6-1089 led to greater localisation of α6β4 to HD and reduced retraction fibre formation, this being reversed by MMP-8 knock-down in N-1089. …”

Finite element solution of monopolar corona on bundle conductors by Al-Hamouz, Z.

“…The effect of the number of bundles, and the bundle spacing on the corona current and ground plane current density profiles is investigated. It has been found that with the increase in the number of bundles, the corona current decreases. …”
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n-Hexadecane Fuel for a Phosphoric Acid Direct Hydrocarbon Fuel Cell by Zhu, YuanChen

“…The objective of this work was to examine fuel cells as a possible alternative to the diesel fuel engines currently used in railway locomotives, thereby decreasing air emissions from the railway transportation sector. …”
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A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater by Azar, Riad

“…Recent series report 5-year postoperative survival rates of 53–68%.7 Successful endoscopic removal of high-grade intraepithelial neoplasia, in situ tumors, and focal T1 cancers has been reported, but is not widely practiced.8, 9 and 10 For patients with slow-growing benign tumors, endoscopic resection is an attractive alternative with decreased cost and morbidity.11 and 12 Endoscopic papillectomy has a recurrence rate of 30% with 13.9% of endoscopically treated patients subsequently undergoing follow-up surgery. …”
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Open carbon frameworks - a search for optimal geometry for hydrogen storage by Kuchta, Bogdan

“…From an analysis of an analytical model and simulations of adsorption the physical limits of hydrogen adsorption have been defined: (i) higher storage capacities in slit-shaped pores can be obtained by fragmentation/truncation of graphene sheets into nano-metric elements which creates surface areas in excess of 2600 m2/g, the surface area for infinite graphene sheets; (ii) the positive influence of increasing surface area is compensated by the decreasing energy of adsorption in the carbon scaffolds of nano-metric sizes; (iii) for open carbon frameworks (OCF) built from coronene and benzene molecules with surface areas 6500 m2 g-1, we find an impressive excess adsorption of 75–110 g H2/kg C at 77 K, and high storage capacity of 110–150 g H2/kg C at 77 K and 100 bar; (iv) the new OCF, if synthesized and optimized, could lead to required hydrogen storage capacity for mobile applications.…”
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Preterm birth in low-middle income Countries by Alim, Swarray-Deen

“…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …”
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Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 by Joan B Soriano (6458528)

“…Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578–4 044 819) in 2017, an increase of 18·0% since 1990, while total DALYs increased by 13·3%. …”

A component analysis of positive behaviour support plans by Grey, Ian

“…Measures of challenging behaviour were taken at baseline, after 6 months, and at an average of 26 months follow-up. …”
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