LDL-C Targets in Secondary Prevention: How Low Should We Go? by Karim Bayoumy (3496688)

“…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …”

Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration by Milane, Aline

“…Cerebral drug transport by ABC transporters in MPTP models has never been reported. Methods: We have investigated the transport of bromocriptine through the blood-brain barrier (BBB) in a MPTP model to understand the influence of the dopaminergic degeneration on ABCB1 and ABCG2. …”
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats by Zeeni, Nadine

“…Furthermore, treatment with BDNF has been found to attenuate weight gain or even cause weight loss and appetite suppression in rats. …”
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Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate by Jou, L.-D.

“…RESULTS: Structural changes of the device have been observed, and it was found that the Pipeline Embolization Device influences the vessel curvature in some cases. …”
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In-Vitro Degradation of Hollow Silica Reinforced Magnesium Syntactic Foams in Different Simulated Body Fluids for Biomedical Applications by Manakari, Vyasaraj

“…Further, the effect of corrosive environment on the degradation behaviour of Mg has been elucidated.…”
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RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells by El Atat, Oula

“…The role of the RHO family GTPase RHOG in angiogenesis in vascular endothelial cells has recently been elucidated. However, the regulation of RHOG during this process, as well as its cross-talk with other RHO GTPases, have yet to be fully examined. …”
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Determinants of dividend payout ratio by Elgammal, Walid

“…Moreover, the study uses the homogeneous subcategory within the purposive sampling since only similar firms in construction industry had been examined. The outcome of the study provides a vital insight into the determinants of dividends payout ratio of companies in MENA region. …”
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Simulation of the size-composition distribution of atmospheric nanoparticles over Europe by David Patoulias (4722960)

“…<p dir="ltr">PMCAMx-UF, a three-dimensional chemical transport model focusing on the simulation of the ultrafine particle size distribution and composition has been extended with the addition of the volatility basis set (VBS) approach for the simulation of organic aerosol (OA). …”

Non-Isolated DC–DC Power Converter With High Gain and Inverting Capability by Mohammad Meraj (16855401)

“…The parasitic of the components has been considered in the analysis to show the deviation from the ideal cases. …”

On-site workshop investment problem: A novel mathematical approach and solution procedure by Nima Moradi (19418821)

“…These temporary OSWs are cost-effective, leading to decreasing the material handling cost and project makespan, which indicates their important role as a part of a construction project. …”

Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update by Maria K. Smatti (4675852)

“…EBV is highly prevalent since it affects more than 90% of individuals worldwide and has been linked to several malignancies including PTLDs, which are one of the most common malignancies following transplantation. …”

Energy saving potential analysis applying factory scale energy audit – A case study of food production by Derar Al Momani (17831981)

“…The CO₂ harmful emissions were also decreased. Additionally, it is estimated that switching from the proposed motors to energy-efficient motors will cost less overall over time, saving around 3472.314 JD/month or 0.33576/year on average. …”

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity by Mohammed R. Shaker (10316180)

“…<p dir="ltr">Klotho, a well-known aging suppressor protein, has been implicated in neuroprotection and the regulation of neuronal senescence. …”

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

“…<div><p>The bioconvection flow of tiny fluid conveying the nanoparticles has been investigated between two concentric cylinders. …”

Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings by Khan, M.S.

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Effect of phosphorus supplementation on weight gain and waist circumference of overweight/obese adults by Bassil, MS

“…Several parameters of subjective appetite scores were decreased in the phosphorus-supplemented group. Conclusions: Phosphorus supplementation for 12 weeks significantly decreases body weight, BMI, waist circumference and subjective appetite scores. …”
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Evaluation of the durability and shielding properties of high-strength concrete incorporating locally available materials and carbon additives by Othman, Obaida

“…High-strength concrete (HSC) has been extensively studied for major applications, particularly in high-rise buildings and bridges. …”
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Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women by Vijay, Ganji

“…Vitamin D deficiency has been linked to increased adiposity and decreased bone density. …”
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Road safety and traffic medicine in Iran: Achievements and challenges by A. Motevalian (19807242)

“…The number decreased to 23000 in 2010 and less than 18000 in 2013. …”