Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent حسب Nasreddine, Ghenwa

"…Addition of excess L-citrulline rescued only one of three cell lines tested, indicating that the majority of cell lines are completely auxotrophic for arginine. …"
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) حسب Khalil, Nathalie

"…In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …"
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Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells حسب Zgheib, Perla

"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the 4 cell lines. …"
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Expanding the donor pool حسب Ramos, Emilio

"…These measures may be beneficial in terms of increasing the number of donors and decreasing the waiting time. …"
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The antioxidant and anticancer effects of Wild Carrot oil extract حسب Shebaby, Wassim Nasri

"…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
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The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013) حسب Zgheib, Perla Z.

"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. …"
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Interactions between riluzole and ABCG2/BCRP transporter حسب Milane, Aline

"…Assays on mdr1a (−/−) mice and BeWo cells showed a higher uptake of riluzole when pretreated with a BCRP inhibitor. After repeated doses of riluzole, BCRP activity was increased in CF1 mdr1a (−/−) mice, riluzole uptake was decrease and both BCRP expression and activity were increased in BeWo cells. …"
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Indoor Air Quality (IAQ) in labor housing in Dubai and its impact on ccupants' health حسب Nazzal, Saja Bassam

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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells حسب Al Sayyed, Fatima

"…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells حسب Shebaby, Wassim N.

"…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …"
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Effect of 7-minute workout on weight and body composition حسب Mattar, L.

"…This implies that even in normal weight individuals who perform the 7-minute workout, improvement through a decrease in waist circumference can be achieved thus leading to a better cardio-protective nutritional status. …"
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Carotid artery revascularization through a radiated field حسب Lesèche, Guy

"…Risk for recurrent stenosis greater than 60% at 18 months was 16.6%. Recurrent stenosis occurred in 2 of these patients after saphenous vein bypass, and in 1 patient after endarterectomy with vein patch angioplasty. …"
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Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion حسب Al-Dimassi, Saleh

"…However, astrocytoma cells that were treated with LeTx showed a significant decrease in cell motility as seen by wound healing as well as random 2D motility in serum. …"
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The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis حسب Mroueh, MA

"…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …"
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Mixed Convection from A Cylinder with Low Conductivity Baffles in Cross-Flow حسب A/K Abu-Hijleh, Bassam

"…When using a small number of baffles at low values of buoyancy parameter, an odd number of baffles reduced the Nusselt number more than an even number of baffles, especially at high values of Reynolds number. …"
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Efficacy and safety of the newer oral hypoglycemic agents in patients with T2DM during Ramadan: A systematic review and meta-analysis حسب Hoda Gad (6470522)

"…Glucagon-like peptide (GLP-1) agonist therapy was associated with a significant decrease in Hb_A1c (%) (SMD -0.68) and a non-significant decrease in weight (kg) (SMD -2.57) and systolic blood pressure (SBP) (mmHg) (SMD -3.50) after Ramadan. …"

Hemodynamics of small aneurysm pairs at the internal carotid artery حسب Jou, Liang-Der

"…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. …"
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy حسب Taki, Fatima

"…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …"
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"

Tabu search based circuit optimization حسب Sait, Sadiq M.

"…Such a strategy leads to sizable circuit speed improvement with minimum increase in the overall circuit capacitance. Compared to earlier approaches, the presented technique produces circuits with remarkable increase in speed (greater than 20%) for very small increase in overall circuit capacitance (less than 3%)…"
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