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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma
Published 2015“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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What drives cryptocurrency pump and dump schemes: Coin versus market factors?
Published 2024“…These include lower market capitalization, lower trading volume, greater social media popularity, increased developer activity, and fewer exchanges trading them. …”
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Thermodynamic Analysis of Integrated Fuel Cell and Solar Energy Systems
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87
Effect of Bentonite Permeation on the Fabric and Strength of Ottawa Sand
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88
Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells
Published 2021“…In this project, we first inspected ASS-1 expression in human breast cancer patients and found that it decreases progressively with tumorigenesis and metastasis. …”
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Distribution and predictors of emergency department charges
Published 2016“…Results: Findings revealed that the professional fee (40.9 %) followed by facility fee (26.1 %) accounted for the majority of the ED charges. While greater than 80 % of visit charges went to physician and facility fee for low acuity cases, these contributed to only 52 and 54 % of the high acuity presentations where ancillary services and solutions’ contribution to the total charges increased. …”
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Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells
Published 2023“…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …”
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Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models
Published 2025“…Using Caco-2 and HT-29 intestinal epithelial cell lines stimulated with Tumor Necrosis Factor-α (TNF-α) or Dextran Sodium Sulfate (DSS) as in vitro models of inflammation, we observed upregulation of ACSS2 protein expression. …”
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Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease
Published 2015“…The combination of olodaterol and tiotropium provided additional improvements in lung function greater than monotherapy with each drug alone. Several well-designed randomized trials confirmed that the synergistic effect of both drugs in combination was able to improve lung function and health-related quality of life without a significant increase in adverse effects. …”
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Evaluating impact of electrified vehicles on fuel consumption and CO2 emissions reduction in Lebanese driving conditions using onboard GPS survey
Published 2011“…This growth is mainly attributed to the raise of daily passenger trips and the increase of car ownership. Moreover, this increase in mobility demand results in severe congestion, mostly in Greater Beirut Area (GBA), which leads to chaotic traffic conditions. …”
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Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles
Published 2023“…<p dir="ltr">Autonomous vehicles offer greater passenger convenience and improved fuel efficiency. …”
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The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
Published 2023“…Europe‘s aging population is increasing, affecting various sectors, including the healthcare system, labor market, and public services. …”
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Context-Tailored Food-Based Nutrition Education and Counseling for Pregnant Women to Improve Birth Outcomes: A Cluster-Randomized Controlled Trial in Rural Malawi
Published 2024“…Intervention infants had greater birth length (P = 0.043) and abdominal circumference (P = 0.007) compared to controls, whereas other birth outcomes did not differ significantly. …”
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Civil Unrest and the Poaching of Rhinos in the Kaziranga National Park, India
Published 2014“…This paper accounts for a period of civil unrest in Assam, India, which saw a marked increase in rhino poaching. Census data on the greater one-horned rhinoceros (Rhinoceros unicornis) in the Kaziranga National Park in Assam are used to estimate a population growth function. …”
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Impact of Plant Life on Formaldehyde Levels in an Existing Office Setting In the UAE
Published 2015“…Recommendations for future research: 1) Conduct the research in a more controlled environment for optimized results. 2) Increase to plant / space ratio in order to achieve greater results.…”
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Dissection of the Genetic and Molecular Pathways of Cleft Lip and Palate
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masterThesis