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661
Towards Industry 4.0 and Sustainable Manufacturing Applying Environmentally Friendly Machining of a Precipitation Hardened Stainless Steel Using Hot Turning Process
منشور في 2023"…In this research, the conventional and hot turning of AISI630 hardened stainless steel have been investigated using PVD-(Ti,Al)N/(Al,Cr)<sub>2</sub>O<sub>3</sub> coated carbide cutting tools at various feed rates and cutting speeds. The high hardness of AISI630, along with the low thermal conductivity, has made it one of the most difficult-to-cut materials, and consequently, its machining is associated with high tool wear and poor workpiece surface quality. …"
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662
The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
منشور في 2023"…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …"
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663
Notes total mesorectal excision (TME) for patients with rectal neoplasia
منشور في 2014"…This approach may lead to reduced postoperative pain, decreased hernia formation and improved cosmesis when compared to standard laparoscopy. …"
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664
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
منشور في 2023"…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …"
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665
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…Findings The global TFR decreased from 2·72 (95% uncertainty interval [UI] 2·66–2·79) in 2000 to 2·31 (2·17–2·46) in 2019. …"
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666
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
منشور في 2021"…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1<sup>KD</sup>) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …"
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667
Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers
منشور في 2023"…Miscible displacements of potassium bromide were observed from a column of 2.0–2.8 mm aggregates of sepiolite over 4 ranges of concentration and at 11 displacement speeds under saturated vertical flow deionized water and vice versa. …"
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668
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
منشور في 2022"…They further establish the SOCE hypomorph line as a genetic model to define the therapeutic window of SOCE inhibition and dissect toxicities associated with chronic SOCE inhibition in a tissue-specific fashion.…"
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669
Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
منشور في 2025"…Results showed that cultivation dominates the process cost: typical biomass costs are $3.54–$5.78/kg in tubular PBRs versus $3.42–$4.13/kg in ORPs; an automation/modularization case decreased microalgae production cost from $89 to $16/kg at ∼200 t/yr. …"
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670
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671
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. …"
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672
Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare
منشور في 2021"…These factors include Performance Expectancy, Effort Expectancy, Social Influence, Facilitating Conditions, Attitude Towards, Behavioral Intention, Use Behavior, Computer Anxiety, Computer Self-Efficacy, Innovativeness, and Trust. In line with the gaps found in the literature, this research has presented a case study for the currently implemented queue management solution (QMS) in the out-patient department (OPD) in a healthcare organization in UAE. …"
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