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621
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
منشور في 2019"…MG was increased in high glucose by increased flux of MG formation linked to increased glucose metabolism mediated by proteolytic stabilisation and increase of hexokinase-2 (HK-2); later potentiated by proteolytic down regulation of glyoxalase 1 (Glo1) - the major enzyme of MG metabolism. …"
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622
Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
منشور في 2024"…For instance, CR has been linked to increased accumulation of bone marrow adipose tissue (BMAT) in long bones, a process thought to elicit detrimental effects on bone. …"
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623
Past and future climate effects on population structure and diversity of North Pacific surfgrasses
منشور في 2024"…Genetic diversity of <i>Phyllospadix torreyi </i>decreases from north to south, but in <i>Phyllospadix scouleri</i> the trend is variable. …"
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624
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…The Q-OHEP also recommended implementing a forecast system using treatment center data based on the supply/demand of formulary oncology drugs to detect treatment patterns, estimate needs, expedite procurement, and prevent shortages/delays. …"
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625
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
منشور في 2018"…Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. Therefore, more selective and efficient therapeutic methods for targeting GBM are needed. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
masterThesis -
626
Thalidomide-Revisited: Are COVID-19 Patients Going to Be the Latest Victims of Yet Another Theoretical Drug-Repurposing?
منشور في 2020"…In the absence of an effective anti-viral molecule and until the formulation of a successful vaccine, anti-inflammatory drugs might offer a complementary tool for controlling the associated complications of COVID-19 and thus decreasing the subsequent fatalities. Drug repurposing for several molecules has emerged as a rapid temporary solution for COVID-19. …"
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627
Investigation of Groundwater Depletion in the State of Qatar and Its Implication to Energy Water and Food Nexus
منشور في 2021"…What are the corrective actions needed to avert the long-term risks in arid environments? …"
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628
Factors Associated with Meeting Current Recommendation for Physical Activity in Scottish Adults with Diabetes
منشور في 2019"…Implementation of health promotion programs that target the identified determinants is needed to improve the recommended levels of physical activity among adults with diabetes.…"
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629
The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar
منشور في 2023"…However, its use has been linked to fetal growth restriction (FGR) as well. …"
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630
A Case Study in Qatar for Optimal Energy Management of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewable Energy and Storage Systems
منشور في 2020"…This interest has focused mainly on reducing the reliance on fossil fuel-based means of transportation and decreasing the harmful emissions produced from this sector. …"
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631
Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases
منشور في 2024"…The laparoscopic approach is reasonable, especially for type 1 MS and noncomplicated cases. Further research is needed to optimize treatment strategies for this challenging condition.…"
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632
Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species
منشور في 2022"…<p dir="ltr">The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …"
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633
Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study
منشور في 2020"…<h3>Background</h3><p dir="ltr">To contribute to the WHO initiative, VISION 2020: The Right to Sight, an assessment of global vision impairment in 2020 and temporal change is needed. We aimed to extensively update estimates of global vision loss burden, presenting estimates for 2020, temporal change over three decades between 1990–2020, and forecasts for 2050.…"
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634
Effects of visual field impairment on driving
منشور في 2015"…Furthermore, the analysis needs to be complemented with an analysis which consider diagnosis and cognitive status.…"
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635
Healthcare Professionals' Attitudes Toward Patients With Mental Illness: A Cross-Sectional Study in Qatar
منشور في 2022"…Stigmatizing attitudes by HCP can have adverse consequences on people with mental illness from delays in seeking help to decreased quality of care provided. Assessing such attitudes is an essential step in understanding such stigma and, if needed, developing and testing appropriate and culturally adapted interventions to reduce it.…"
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636
Effectiveness of external myofascial mobilisation in the management of male chronic pelvic pain of muscle spastic type: A retrospective study
منشور في 2021"…Future high-quality studies with control groups are needed to confirm the present findings. Durability and long-term results are yet to be determined.…"
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637
Structural and Durability Performance of 3D Concrete Printing
منشور في 2023احصل على النص الكامل
doctoralThesis -
638
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
منشور في 2022"…In order to control fine particles transport in porous media, the behavior itself needs to be predicted and analyzed. Which could be quite costly to do in a laboratory experiment, hence the modelling of such a behavior would be an optimum way to study. …"
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639
Immunoprofile of childhood diabetes
منشور في 2023"…In order to be functional, the CD49d integrin needs to form a heterodimer with ITGB1 protein. When transcriptomic data was interrogated, an imbalance between ITGA4/ ITGB1 was observed in all groups where CD49d showed increased expression. …"
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640
Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers
منشور في 2023"…Modeling the trends of saltwater intrusion needs theoretical understanding and thorough logical experimentation. …"