Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31 حسب Jonathan D. J. Labonne (18090841)

"…RT-qPCR assays revealed that LRRK2 transcripts were dramatically reduced in our microdeletion patient DGDP289A compared to his healthy grandfather with no deletion. The decreased expression of LRRK2 may affect protein–protein interactions between LRRK2 and its binding partners, of which eight have previously been linked to intellectual disability. …"

Healthcare Professionals' Attitudes Toward Patients With Mental Illness: A Cross-Sectional Study in Qatar حسب Suhaila Ghuloum (796180)

"…<h3>Background</h3> <p>Negative attitudes toward mental illness by Health Care Professionals (HCP) have been reported in many countries across the world. …"

Removal of Benzene and Toluene from Synthetic Wastewater by Adsorption onto Magnetic Zeolitic Imidazole Framework Nanocomposites حسب George Z. Kyzas (740387)

"…<p dir="ltr">Considering the risk associated with exposure to benzene and toluene in water resources, researchers have been motivated to conduct studies to remove them from aqueous solutions. …"

Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies حسب Sabah Nisar (12561961)

"…Emerging research has identified multifaceted roles of circRNAs as miRNA and RNA binding protein (RBP) sponges and transcription, translation, and splicing event regulators. CircRNAs have been involved in many human illnesses, including cancer and neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease, due to their aberrant expression in different pathological conditions. …"

Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey حسب Ahmad Salman (3173418)

"…The objective of this study was to assess the prevalence and determinants of meeting recommended levels of PA among older adults with multimorbidity. Data has been derived from the nationally representative Scottish Health Surveys (2014–2017). …"

Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H₂S: DFT study حسب Ehab Salih (17075206)

"…Moreover, the adsorption distance (D) between H₂S and Cu/Zn-ZGNR decreased remarkably to 2.23 Å and an S–Cu bond was generated. …"

Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women حسب Vijay Ganji (8710491)

"…<p dir="ltr">Vitamin D deficiency has been linked to increased adiposity and decreased bone density. …"

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…The Chemokine (C-C motif) ligand 5 (CCL5) and its signaling pathway have been linked to TNBC. We aimed to investigate the susceptibility and prognostic implications of genetic variation in CCL5 signaling genes in TNBC in the present study. …"

Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank حسب Al-Hamdani, Mohammed

"…The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is used to assess the severity of symptoms related to pain, stiffness, and function in diseased hip and knee joints. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 حسب Kanyin Liane, Ong

"…By 2050, 89 (43·6%) of 204 countries and territories will have an age-standardised rate greater than 10%. InterpretationDiabetes remains a substantial public health issue. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Examining time-to-transport decisions in Emergency Medical Services حسب Hassan Farhat (9000509)

"…While considerable efforts have been made to investigate emergency care and timing within the Emergency Medical Service (EMS)1,2,3, the subtleties surrounding time-to-transport decisions remain underexplored. …"

The immune landscape of solid pediatric tumors حسب Shimaa Sherif (12862990)

"…<h3>Background</h3><p dir="ltr">Large immunogenomic analyses have demonstrated the prognostic role of the functional orientation of the tumor microenvironment in adult solid tumors, this variable has been poorly explored in the pediatric counterpart.…"

COVID-19 may have increased global support for universal health coverage: multi-country observational study حسب Claudia F. Nisa (11346055)

"…</p><h3 dir="ltr">Conclusion</h3><p dir="ltr">The COVID-19 pandemic may have been a potential turning point in the global public support for UHC, as evidenced by a higher level of consensus that governments should be guarantors of healthcare.…"

Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials حسب Yara Wanas (8744844)

"…<h3>Background</h3><p dir="ltr">Angiotensin receptor blockers (ARBs) are commonly used as a treatment for many cardiovascular diseases, but their safety has been called into question. The VALUE trial found an increased risk of myocardial infarction in participants receiving ARBs compared to other antihypertensive. …"

Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance حسب Mohammed Hamidat (3722086)

"…Various solutions have been developed to address this problem and mitigate the impact of wind energy fluctuations, such as the deployment of Flywheel Energy Storage Systems (FESSs). …"

Effect of Surface Treatment of Halloysite Nanotubes (HNTs) on the Kinetics of Epoxy Resin Cure with Amines حسب Vahideh Akbari (18768001)

"…<p dir="ltr">The epoxy/clay nanocomposites have been extensively considered over years because of their low cost and excellent performance. …"

Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish حسب Fatiha M. Benslimane (6695087)

"…In the last few decades, echocardiography has been applied to <i>in vivo</i> cardiac disease models, mainly to rodents. …"

The effect of indoor air quality on health and performance of labors in joinery factories حسب Sadeghi, Hengameh

"…The growing population and the rising number of investors have a huge impact on the construction industry, and the demand for joinery items will increase. Wood has been well known for thousands of years as one of the first few natural renewable resources in the world (Rastogi et al. 1989). …"
احصل على النص الكامل

ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder حسب Sara Cuvertino (18892069)

"…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …"

Recovery of business intelligence systems حسب Haraty, Ramzi A.

"…Although there are many defensive security methods that have been devised, nonetheless malicious transactions may find a way to penetrate the secured safeguard and then modify critical data of healthcare databases. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل