Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …”
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Exploring the potential of single-batch and multi-batch electrodialysis treatment of domestic wastewater for resource recovery by Asifa Anwar (20884229)

“…Nevertheless, the hydrogen generation rate was greater in SB-ED at 629.4 mg/h.m³ in comparison to 540.7 mg/h.m³ for MB-ED. …”

Adsorption of ammonia on ZrO_<em>x</em>-modified graphene nanoribbon: a first-principle investigation by Ahmad I. Ayesh (10188469)

“…Although the adsorption energy is enhanced in general upon modification, AGNR structures where ZrO_x substitute carbon atoms exhibit greater adsorption energy as compared with the decoration scheme. …”

Investigation of co-pyrolysis blends of camel manure, date pits and plastic waste into value added products using Aspen Plus by Aisha Al-Rumaihi (17269240)

“…<p>The increasing demand for energy worldwide and growing environmental concerns is the impetus for greater integration of alternate sustainable technologies. …”

Reducing injuries among young drivers: what kind of measures are needed? by Hans-Yngve Berg (19794540)

“…<p dir="ltr">Young drivers run a greater risk everywhere. Better understanding of the underlying processes to this problem are a useful tool in preventive endeavors. …”

Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs) and Ultrasound. by Ibrahim, Mihad

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The Integration of Agile Methodology in the Development of Software Project by ALMHEIRI, MOHAMMED

“…Agile proponents have produced a number of assertions regarding the advantages of agile approaches, such as increased group productivity and effectiveness, improved software reliability, and business effectiveness. …”
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging by Dimassi, Hani

“…Children with white-matter abnormalities and increased tone had a greater frequency of increased reflexes and tended to have more signal abnormalities than the other groups. …”
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Forecasting the impact of diabetes mellitus on tuberculosis disease incidence and mortality in India by Susanne F Awad (18618622)

“…Targeting the impact of the increasing DM burden on TB control is critical to achieving the goal of TB elimination by 2050.…”

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

“…SLC7A8/SLC3A2 heterodimer is a neutral amino acid exchanger. Here, we demonstrated that SLC7A8 is expressed in the mouse inner ear and that its ablation resulted in ARHL, due to the damage of different cochlear structures. …”

Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

“…<p dir="ltr">Accumulation of α-synuclein into toxic oligomers or fibrils is implicated in dopaminergic neurodegeneration in Parkinson’s disease. Here we performed a high-throughput, proteome-wide peptide screen to identify protein-protein interaction inhibitors that reduce α-synuclein oligomer levels and their associated cytotoxicity. …”

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia by Ali Zaki Ibrahim (17092957)

“…<p dir="ltr">Propionic Acidemia (PA) is an inborn error of metabolism caused by variants in the PCCA or PCCB genes, leading to mitochondrial accumulation of propionyl-CoA and its by-products. Here, we report a 2 year-old Egyptian boy with PA who was born to consanguineous parents. …”

The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study by Aksam Yassin (14779204)

“…Whilst the benefits of testosterone (T) replacement are well-evidenced, the long-term data for TTh on metabolic and endocrine parameters is limited. Here we present the effect of TTh on endocrine parameters in hypogonadal men at a 12-year follow-up. …”

CRISPR-Cas Controls Cryptic Prophages by Sooyeon Song (4891132)

“…<div><p>The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. …”

Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity by Vijay Gupta (209146)

“…Therefore, the scFvs described here have considerable potential to be utilized towards immunotherapy in synucleinopathies and may also have applications in ante-mortem imaging modalities.…”

The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere by Sara H. Al-Hadidi (17821196)

“…<p dir="ltr">The date palm (<i>Phoenix dactylifera</i>) is an important cultivated crop in arid areas. Here, we studied the effect of plant genotype and type of fertilizers on the eukaryotic community structures of the date palm rhizosphere. …”

PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development by Sahar I. Da’as (9631717)

“…<p dir="ltr">Recessive mutations in Post-GPI attachment to proteins 3 (PGAP3) cause the rare neurological disorder hyperphosphatasia with mental retardation syndrome 4 type (HPMRS4). Here, we report a novel homozygous nonsense mutation in PGAP3 (c.265C>T-p.Gln89*), in a 3-year-old boy with unique novel clinical features. …”

Damage and life cycle assessment of new-generation wide-base tires in New Brunswick, Canada. (c2017) by Said, Izak

“…After combining the distresses considered, pavement damage increased as NGWBT market penetration became greater; for a case study with market penetration of 20%, damage increment due to NGWBT increased by 8%. …”
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The effect of ZrOx modification of graphene nanoribbon on its adsorption for NOx: A DFT investigation by Ahmad I. Ayesh (10188469)

“…Herein, the adsorption energy of AGNR doped using ZrO₂ for NO increases 26.9 times while it increases 19.6 times for NO₂ as compared with those of the pure structure. …”

The Efficacy of Lubiprostone in Patients of Constipation: An Updated Systematic Review and Meta‐Analysis by Umar Akram (20151411)

“…<h3>Background and Aim</h3><p dir="ltr">Lubiprostone increases chloride and water secretion in the intestines, and several studies have demonstrated the efficacy of lubiprostone in treating functional constipation. …”