Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs) and Ultrasound. by Ibrahim, Mihad

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The Integration of Agile Methodology in the Development of Software Project by ALMHEIRI, MOHAMMED

“…Agile proponents have produced a number of assertions regarding the advantages of agile approaches, such as increased group productivity and effectiveness, improved software reliability, and business effectiveness. …”
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging by Dimassi, Hani

“…Children with white-matter abnormalities and increased tone had a greater frequency of increased reflexes and tended to have more signal abnormalities than the other groups. …”
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Forecasting the impact of diabetes mellitus on tuberculosis disease incidence and mortality in India by Susanne F Awad (18618622)

“…Targeting the impact of the increasing DM burden on TB control is critical to achieving the goal of TB elimination by 2050.…”

Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

“…<p dir="ltr">Accumulation of α-synuclein into toxic oligomers or fibrils is implicated in dopaminergic neurodegeneration in Parkinson’s disease. Here we performed a high-throughput, proteome-wide peptide screen to identify protein-protein interaction inhibitors that reduce α-synuclein oligomer levels and their associated cytotoxicity. …”

Vitamin D association with coagulation factors in polycystic ovary syndrome is dependent upon body mass index by Abu Saleh Md Moin (6189512)

“…<p dir="ltr">Polycystic ovary syndrome (PCOS) is associated with metabolic consequences including obesity and insulin resistance that are related to the excess prevalence of type 2 diabetes, hypertension, and cardiovascular diseases in later life. It is reported that PCOS subjects show marked platelet dysfunction and decreased plasma fibrinolytic activity, resulting in a prothrombotic state. …”

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia by Ali Zaki Ibrahim (17092957)

“…<p dir="ltr">Propionic Acidemia (PA) is an inborn error of metabolism caused by variants in the PCCA or PCCB genes, leading to mitochondrial accumulation of propionyl-CoA and its by-products. Here, we report a 2 year-old Egyptian boy with PA who was born to consanguineous parents. …”

Meta-Heuristic Algorithm-Tuned Neural Network for Breast Cancer Diagnosis Using Ultrasound Images by Ahila A (18394806)

“…Early diagnosis is the only way to increase the treatment options which then decreases the death rate and increases the chance of survival in patients. …”

The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study by Aksam Yassin (14779204)

“…Whilst the benefits of testosterone (T) replacement are well-evidenced, the long-term data for TTh on metabolic and endocrine parameters is limited. Here we present the effect of TTh on endocrine parameters in hypogonadal men at a 12-year follow-up. …”

CRISPR-Cas Controls Cryptic Prophages by Sooyeon Song (4891132)

“…<div><p>The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. …”

Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity by Vijay Gupta (209146)

“…Therefore, the scFvs described here have considerable potential to be utilized towards immunotherapy in synucleinopathies and may also have applications in ante-mortem imaging modalities.…”

The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere by Sara H. Al-Hadidi (17821196)

“…<p dir="ltr">The date palm (<i>Phoenix dactylifera</i>) is an important cultivated crop in arid areas. Here, we studied the effect of plant genotype and type of fertilizers on the eukaryotic community structures of the date palm rhizosphere. …”

PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development by Sahar I. Da’as (9631717)

“…<p dir="ltr">Recessive mutations in Post-GPI attachment to proteins 3 (PGAP3) cause the rare neurological disorder hyperphosphatasia with mental retardation syndrome 4 type (HPMRS4). Here, we report a novel homozygous nonsense mutation in PGAP3 (c.265C>T-p.Gln89*), in a 3-year-old boy with unique novel clinical features. …”

Damage and life cycle assessment of new-generation wide-base tires in New Brunswick, Canada. (c2017) by Said, Izak

“…After combining the distresses considered, pavement damage increased as NGWBT market penetration became greater; for a case study with market penetration of 20%, damage increment due to NGWBT increased by 8%. …”
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The effect of ZrOx modification of graphene nanoribbon on its adsorption for NOx: A DFT investigation by Ahmad I. Ayesh (10188469)

“…Herein, the adsorption energy of AGNR doped using ZrO₂ for NO increases 26.9 times while it increases 19.6 times for NO₂ as compared with those of the pure structure. …”

The Efficacy of Lubiprostone in Patients of Constipation: An Updated Systematic Review and Meta‐Analysis by Umar Akram (20151411)

“…<h3>Background and Aim</h3><p dir="ltr">Lubiprostone increases chloride and water secretion in the intestines, and several studies have demonstrated the efficacy of lubiprostone in treating functional constipation. …”

CFD modeling of particle settling in drilling fluids: Impact of fluid rheology and particle characteristics by Abdelrahman M. Awad (16932519)

“…Ellipsoidal cuttings exhibited significantly greater resistance to settling as compared to spherical particles, mainly due to the increased drag force. …”

Anteriolateral versus anterior–posterior electrodes in external cardioversion of atrial fibrillation: A systematic review and meta‐analysis of clinical trials by Karam R. Motawea (13954362)

“…The pooled analysis showed a statistically significant association between anterior–lateral electrode and increased cardioversion rate of AF (odds ratio [OR] = 1.40, 95% confidence interval [CI] = 1.02–1.92, <i>p</i> = .04). …”

The impact of counseling on nutritional status among hematopoietic stem cell recipients: results of a randomized controlled trial by Jabbour, Jana

“…Studies assessing malnutrition rates in HSCT showed that malnutrition rates are low at admission (ranging between 4 and 6%), elevated at hospital discharge (ranging between 35 and 60%), and gradually decreases post discharge [2, 3]. A prospective cohort study suggested that even though patients had improved quality of life, physical activity levels, and lean body mass post HSCT, they did not regain their pre-HSCT levels 100 days post transplantation compared to admission. …”
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Properties and Microstructure Distribution of High-Performance Thermal Insulation Concrete by Malek Mohammad (17150977)

“…This material allows for better thermal insulation properties, thus decreasing the energy usage within the life cycle of the concrete structure. …”