The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc... حسب Thozhukat Sathyapalan (704787)

"…Following the 12 week randomization; both group of women with PCOS were subsequently started on metformin 1,500 mg daily for further 12 weeks to assess whether pre-treatment with atorvastatin potentiates the effects of metformin on markers of adipose tissue function We conducted a post-hoc review to detect plasma ASP and the pro-inflammatory cytokines IL6 and MCP-1 before and after 12 and 24 weeks of treatment.</p><h3>Results</h3><p dir="ltr">There was significant reduction in ASP (156.7 ± 16.2 vs. 124.4 ± 14.8 ng/ml p <0.01), IL-6 (1.48 ± 0.29 vs.0.73 ± 0.34 pg/ml p = 0.01) and MCP-1 (30.4 ± 4.2 vs. 23.0 ± 4.5 pg/ml p = 0.02) after 12 weeks of atorvastatin that was maintained subsequently with 12 weeks treatment with metformin. …"

Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response حسب Noura Al-Zeheimi (5177066)

"…To further identify the role of NRP-1 and its interacting molecules in correspondence with patients' response to neoadjuvant chemotherapy (NAC), we conducted a comparative study on blood and tissue samples collected from a cohort of locally advanced breast cancer patients, before and after neoadjuvant chemotherapy (NAC). From a panel of tested proteins and genes, we found that the levels of plasma NRP-1, placenta growth factor (PlGF) and immune cell expression of the transcription factor <i>SNAI1</i> before and after NAC were significantly different. …"

Positional and dimensional temporomandibular joint osseous changes in patients treated with the forsus fatigue resistant device: a non-randomized clinical trial حسب Ramy Abdul-Rahman Ishaq (22928974)

"…Participants were divided into a treatment and a control group. After alignment and leveling with fixed orthodontic appliances using 0.019 × 0.025-inch stainless-steel archwires, the FFRD was fitted. …"

Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth حسب Felipe, Torquato

"…A step further is now required to determine whether these platform foundations should be converted to reefs after their decommissioning (i.e., Rigs to Reefs approach).…"
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Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function حسب Muge Sarper (3855454)

"…Conversely, knock-down of MMP-8 in N-1089 reduced adhesion and increased migration. Expression of MMP-8 WT in β6-1089 led to greater localisation of α6β4 to HD and reduced retraction fibre formation, this being reversed by MMP-8 knock-down in N-1089. …"

Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment حسب Farhat, Peter

"…The aforementioned results explore the efficiency of our proposed scheme in scheduling the fogs in their rightful place, which helps in decreasing the cloud’s load, decreasing the network congestion, and increasing the overall quality of service. …"
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n-Hexadecane Fuel for a Phosphoric Acid Direct Hydrocarbon Fuel Cell حسب Zhu, YuanChen

"…The objective of this work was to examine fuel cells as a possible alternative to the diesel fuel engines currently used in railway locomotives, thereby decreasing air emissions from the railway transportation sector. …"
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Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 حسب Joan B Soriano (6458528)

"…Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578–4 044 819) in 2017, an increase of 18·0% since 1990, while total DALYs increased by 13·3%. …"

Prognostic effects of cardiopulmonary resuscitation (CPR) start time and the interval between CPR to extracorporeal cardiopulmonary resuscitation (ECPR) on patient outcomes under e... حسب Amir Vahedian-Azimi (11177056)

"…These outcomes included longer CPR duration (OR: 1.779, 95%CI: 1.218–2.605, <i> P</i> = 0.034) and decreased survival rates for ECMO at 24 h (OR: 0.561, 95%CI: 0.183–0.903,<i> P</i> = 0.009) and 28 days (OR: 0.498, 95%CI: 0.106–0.802, <i> P</i> = 0.011). …"

A component analysis of positive behaviour support plans حسب Grey, Ian

"…Measures of challenging behaviour were taken at baseline, after 6 months, and at an average of 26 months follow-up. …"
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Cdc42 regulates migration, invadopodia formatio and invasion in glioblastoma cells. (c2018) حسب Masri, Zeinab S El

"…Our data showed that Cdc42 decreases cell adhesion by downregulating RhoA and Rac1. …"
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Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models حسب Ben Romdhane, Haifa

"…Furthermore, results demonstrated that the probability of severe damage increases with decreasing water oxygenation and with increasing temperature, light, salinity, acidity and nutrient levels. …"
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Influence of direct electric field on PMCG-alginate-based microcapsule حسب Peter Kasak (1360617)

"…Microcapsules showed swelling and decreasing mechanical properties under the applied electric current, and the microcapsule membrane showed anisotropic swelling on the electrode side. …"

Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful? حسب Abdalla, Eddie K.

"…Importantly, bevacizumab decreases the incidence and severity of sinusoidal injury with oxaliplatin therapy. …"
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Acute spasticity in malignant MCA stroke: a case report and review of literature حسب Muhammad Faizan (12710607)

"…Spasticity, a common sequela of stroke, typically occurs days to weeks after the initial event. However, an acute onset of spasticity at presentation is extremely rare. …"

Using a Cavitation Model to Represent the Acoustic Release Kinetics from Folated Micelles حسب Tanbour, Rafeeq Kamal

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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis حسب Meritxell Espino‐Guarch (22565774)

"…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …"

Fracture Behavior of ASTM A633 steel plate specimens with edge crack at tensile test حسب Abi Shdid, Caesar

"…This paper evaluates the effect of crack length on the load-displacement curve and also fracture behavior of steel specimens is investigated after tensile tests. Results show that with crack length increasing, yield strength, the ultimate tensile strength, and fracture stress show a decreasing trend. …"
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Non-Isolated DC–DC Power Converter With High Gain and Inverting Capability حسب Mohammad Meraj (16855401)

"…To reduce the ripple in the input current with simultaneous decreasing the input current ripple, a novel current fed interleaved high gain converter is proposed by utilizing the interleaved front-end structure and Cockcroft Walton (CW)-Voltage Multiplier (VM). …"

Investigation of Groundwater Depletion in the State of Qatar and Its Implication to Energy Water and Food Nexus حسب Hazrat Bilal (7367477)

"…This study attempts to investigate the impacts of local and regional climatic trends, and establish key forcing functions that have changed local groundwater resources. The main questions answered through this study include: Are these changes beneficial or detrimental? …"