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421
NLRP7 inter-domain interactions
Published 2014“…Upon activation, the NAD and a small part of the leucine rich repeat (LRR) of one molecule emerged out of the protective LRR domain and interact with the NACHT domain of the second molecule to form an oligomer. …”
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422
Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
Published 2018“…Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …”
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423
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”
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424
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425
Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation
Published 2024“…Clostridioides difficile infection (CDI) induces severe intestinal inflammation, mediated partly by the NF-κB signaling pathway. Flagellin (FliC), a major component of C. difficile flagella, plays a pivotal role in host-pathogen interactions by inducing inflammation via Toll-like receptor 5 (TLR5). …”
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426
Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta...
Published 2023“…Furthermore, there is a belief in the importance of the task forces within the community as part of an emergency response plan, and a less reflective system would have less recovery speed. …”
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427
Influence of co-current vapor flow on falling film over horizontal tube
Published 2021“…<p>In the multi-effect evaporator (MED), the seawater falls on the outside of the tube, and the heat is transmitted from the steam flowing inside the tube. As a result, part of seawater evaporates and vapor is generated. …”
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428
Driving against the clock: Investigating the impacts of time pressure on taxi and non-professional drivers’ safety and compliance
Published 2024“…<p>Drivers often encounter time pressure, which can lead to riskier driving habits, decreased safety margins, and a higher chance of accidents. …”
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429
Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution
Published 2022“…EI offers the determination of users that are part of a multicast session based on location, session, and cell information. …”
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430
Evaluation of high-temperature reverse osmosis for recycling boiler blowdown in industrial applications
Published 2024“…<p dir="ltr">Boilers are key component of industrial plants due to their ability to generate steam to be used in various plant unit processes. As part of boiler's operation, a waste stream is generated, known as blowdown, which is discharged at high temperatures (80-100°C) requiring cooling before treatment and/or disposal. …”
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431
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432
Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making
Published 2019“…In contrary, for every one unit increase in concern scores, the odds of enrollment decreased among study participants by 0.98 [0.97–0.99], adj.P = 0.017. …”
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433
Recovery of business intelligence systems
Published 2018“…In the worst case, the proposed algorithm takes 8.81 ms to discover the damaged part of the database; however, the fastest recent algorithm requires 50.91 ms. …”
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434
Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2022“…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …”
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435
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2021“…</p><p><br></p><h3>Methods</h3><p dir="ltr">We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. …”
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436
Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
Published 2024“…MethodsThe age, sex and year-wise estimates of incidence, mortality, and disability-adjusted life years (DALYs) of 29 cancers for 49 Asian countries from 1990 through 2019 were generated as a part of the Global Burden of Disease, Injuries and Risk Factors 2019 study. …”
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437
Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021
Published 2024“…This analysis, completed as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, methodically accounted for different stillbirth definitions with the aim of comprehensively estimating all stillbirths at 20 weeks or longer for 204 countries and territories from 1990 to 2021. …”
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438
New media and new practices of exploitation
Published 2015“…Employees might be categorized in four different groups: Regular, contracted, part time and freelancer. These categories might be observed both in big media companies and boutique media initiatives at the same time However, there is a new and rising category which is not contracted and highly exploited: Prosumers. …”
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