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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
Published 2021“…Additionally, self-expandable valves were associated with a higher decrease in gradient than balloon ones (beta = 0.38; 95% CI [0.12–0.64]). …”
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Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells
Published 2015“…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …”
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124
What drives cryptocurrency pump and dump schemes: Coin versus market factors?
Published 2024“…These include lower market capitalization, lower trading volume, greater social media popularity, increased developer activity, and fewer exchanges trading them. …”
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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …”
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SynergyGrids: blockchain-supported distributed microgrid energy trading
Published 2022“…The trading system shows 17.8% decrease in energy cost for consumers and 76.4% decrease in load over utility grids when compared with its counterparts.…”
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1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH
Published 2010“…RESULTS No drug-related SAEs or Grade 3 or higher AEs were observed in either study. Most AEs were mild to moderate and transient with no effect on erectile function. …”
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Performance of Different Concrete Types Exposed to Elevated Temperatures: A Review
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129
Distribution and predictors of emergency department charges
Published 2016“…Results: Findings revealed that the professional fee (40.9 %) followed by facility fee (26.1 %) accounted for the majority of the ED charges. While greater than 80 % of visit charges went to physician and facility fee for low acuity cases, these contributed to only 52 and 54 % of the high acuity presentations where ancillary services and solutions’ contribution to the total charges increased. …”
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Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia
Published 2020“…CURB-65 criteria were used to assess the severity of pneumonia. A decrease in CRP levels on days 1 and 3, LOS, and normalization of fever were used to assess the response to antibiotics. …”
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131
A comparison of metals in sediments and water in the River Nahr-Ibrahim, Lebanon
Published 2003“…Water pH and temperature were determined in situ. Sediment samples were dried at room temperature and sieved; the sediment size < 75µm size was retained. …”
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Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis
Published 2023“…We found that 159 patients were matched in group I, 505, and 639 were in groups II and III of AAS, respectively. …”
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Daucus Carota oil extract, a chemotherapeutic agent, acts as an antidepressant that promotes resilience to chronic social defeat stress
Published 2021“…A decrease in the hippocampal p-Akt protein levels is observed in depressed subjects. …”
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Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease
Published 2015“…The combination of olodaterol and tiotropium provided additional improvements in lung function greater than monotherapy with each drug alone. Several well-designed randomized trials confirmed that the synergistic effect of both drugs in combination was able to improve lung function and health-related quality of life without a significant increase in adverse effects. …”
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Evaluating impact of electrified vehicles on fuel consumption and CO2 emissions reduction in Lebanese driving conditions using onboard GPS survey
Published 2011“…This growth is mainly attributed to the raise of daily passenger trips and the increase of car ownership. Moreover, this increase in mobility demand results in severe congestion, mostly in Greater Beirut Area (GBA), which leads to chaotic traffic conditions. …”
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137
Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles
Published 2023“…<p dir="ltr">Autonomous vehicles offer greater passenger convenience and improved fuel efficiency. …”
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …”
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Context-Tailored Food-Based Nutrition Education and Counseling for Pregnant Women to Improve Birth Outcomes: A Cluster-Randomized Controlled Trial in Rural Malawi
Published 2024“…Intervention infants had greater birth length (P = 0.043) and abdominal circumference (P = 0.007) compared to controls, whereas other birth outcomes did not differ significantly. …”
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Civil Unrest and the Poaching of Rhinos in the Kaziranga National Park, India
Published 2014“…This paper accounts for a period of civil unrest in Assam, India, which saw a marked increase in rhino poaching. Census data on the greater one-horned rhinoceros (Rhinoceros unicornis) in the Kaziranga National Park in Assam are used to estimate a population growth function. …”
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