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421
3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations
منشور في 2022"…<p dir="ltr">Despite the efforts devoted to drug discovery and development, the number of new drug approvals have been decreasing. Specifically, cardiovascular developments have been showing amongst the lowest levels of approvals. …"
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422
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
منشور في 2022"…The time required to develop bridging and subsequent clogging of the pore space that lead to permeability reduction decreases as the flow velocity increases. The size of the fine particles has a significant impact on permeability reduction where the reduction in permeability increases as the size of particles increases. …"
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423
Immunoprofile of childhood diabetes
منشور في 2023"…When transcriptomic data was interrogated, an imbalance between ITGA4/ ITGB1 was observed in all groups where CD49d showed increased expression. Associated with these findings, anti-inflammatory Treg cytokines including IL-10 were decreased in T2D patients and elevated plasma levels of IL-17, which contributes to the insulin resistance and inflammation were observed.…"
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424
One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes
منشور في 2022"…After the first 3 months of HCL use, patients were followed at 6, 9 and 12 months, where HbA1c was obtained and pump data were collected.…"
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425
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426
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427
Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease St...
منشور في 2025"…From 2022 to 2050, global increases in overweight (not obesity) prevalence are forecasted to stabilise, yet the increase in the absolute proportion of the global population with obesity is forecasted to be greater than between 1990 and 2021, with substantial increases forecast between 2022 and 2030, which continue between 2031 and 2050. …"
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428
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
منشور في 2021"…Considering the combining role of the RH and chemical composition in aerosol phase state, the BF decreased monotonically with increasing hygroscopic growth factor (GF), and the BF was ∼ 0 when GF was larger than 1.15. …"
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429
Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming
منشور في 2024"…<p dir="ltr">CO<sub>2</sub> reforming of methane was investigated using trace noble metal anchored MgO-promoted Ni/La<sub>2</sub>O<sub>3</sub> catalyst (LaNiMgO-X), where X = Ir, Pt, Ru, Pd, and Rh. The incorporation of noble metals enhanced Ni dispersion on the support and facilitated the Ni reducibility due to the H<sub>2</sub> spillover effect. …"
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430
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431
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432
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433
The investigation of treatment design parameters on carbon integration networks
منشور في 2023"…However, there was a noticeable linear trend at lower temperatures compared to higher temperatures, where the increase became non-linear. Furthermore, it was discovered that for net capture targets of 20% and 25%, no revenue from carbon storage could be generated beyond a solvent temperature of 25 °C. …"
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434
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435
A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater
منشور في 2011"…Lymph node involvement was predictive of recurrence and decreased survival. Conclusion Patients with malignant tumors often present with jaundice and larger tumors. …"
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436
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437
The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
منشور في 2019"…This was a randomized, double-blind, placebo-controlled study where 40 medication-naive women with PCOS and biochemical hyperandrogenaemia were randomized to either atorvastatin 20 mg daily or placebo for 12 weeks. …"
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438
Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer
منشور في 2007"…The tumor-to-muscle ratio decreased in mice pretreated with trastuzumab and in mice injected with IRDye 800CW and (111In-DTPA)p-IgG-(IRDye800)q. …"
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439
Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas...
منشور في 2021"…Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. …"
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440