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261
Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
منشور في 2020"…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …"
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masterThesis -
262
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
منشور في 2022"…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"
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263
Country of birth affects blood pressure in the French hypertensive diabetic population
منشور في 2015"…The combination of diabetes and hypertension in African populations was associated with increased aortic stiffness and PP, together with greater body weight and WHR. …"
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264
Notes total mesorectal excision (TME) for patients with rectal neoplasia
منشور في 2014"…This approach may lead to reduced postoperative pain, decreased hernia formation and improved cosmesis when compared to standard laparoscopy. …"
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265
Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
منشور في 2010"…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …"
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266
Numerical Investigation of Flexural Behavior of Reinforced Concrete (RC) T-Beams Strengthened with Pre-Stressed Iron-Based (FeMnSiCrNi) Shape Memory Alloy Bars
منشور في 2023"…Based on the numerical results, it was found that increasing the compression strength from 30 to 60 MPa slightly improves the beam’s strength (by 2%), but it significantly increases its ductility by approximately 45%. …"
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267
Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus
منشور في 2017"…Mortality was significantly greater among diabetic than nondiabetic hypertensive subjects (all-cause mortality, 14.05% versus 7.43%; and cardiovascular mortality, 1.28% versus 0.7%). …"
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268
Five-Level MLI-Based Grid-Connected Photovoltaic Systems: A Review on Control Methodologies, Modulation Strategies and Recent Developments
منشور في 2024"…Five-level MLI-based PV systems have become a crucial option as the relevance of renewable energy keeps increasing because of their increased efficiency, less harmonic distortion, and greater power quality. …"
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269
Impacts of Diverse Workforce on Cyber Security and Information Technology Management
منشور في 2023"…Despite these findings, organizations should continue to consider the potential benefits of diversity in the cybersecurity workforce, including improved decision-making, increased adaptability, enhanced creativity, greater representation, and improved team performance. …"
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270
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
منشور في 2015"…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …"
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271
Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma
منشور في 2015"…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …"
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272
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
منشور في 2024"…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …"
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273
Effect of StarD13 on colorectal cancer proliferation, motility and invasion
منشور في 2014"…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …"
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274
Disciplinary action against physicians: Who is likely to get disciplined?
منشور في 2005"…Kaplan-Meier analysis revealed that the proportion of physicians disciplined increased with each successive 10-year interval since first licensure. …"
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275
Transnational activism in Lebanon's women's movement. (c2013)
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masterThesis -
276
Yeast Cell Adhesion Molecules Have Functional Amyloid-Forming Sequences
منشور في 2010"…These sequences had an unusual amino acid composition: 77% of their residues were β-branched aliphatic amino acids Ile, Thr, and Val, which is more than 4-fold greater than their prevalence in the S. cerevisiae proteome. …"
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277
Critical Review on Nanofluids: Preparation, Characterization, and Applications
منشور في 2016"…A “nanofluid” is a fluid with suspended fine nanoparticles which increases the heat transfer properties compared with the original fluid. …"
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278
Potential of GTL-Derived Biosolids for Water Treatment: Fractionization, Leachate, and Environmental Risk Analysis
منشور في 2022"…Characterization showed an increased carbon content and reduced oxygen content in the biochar sample. …"
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279
Diversity of hydrocarbon-degrading bacteria isolated from the rhizosphere of mangrove forests in two coastal regions of Qatar
منشور في 2025"…In contrast, Al Thakhirah exhibited greater bacterial diversity, including <i>Lysinibacillus xylanilyticus</i> and <i>Acinetobacter calcoaceticus</i>. …"
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280