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401
Renal Function Decline in Recipients and Donors of Kidney Grafts
Published 2015“…Background/Aims: Renal function decreases over time as a result of reduction in the number of functioning nephrons with age. …”
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402
Blockchain, climate damage, and death: Policy interventions to reduce the carbon emissions, mortality, and net-zero implications of non-fungible tokens and Bitcoin
Published 2022“…</p><p dir="ltr">Nonetheless, many popular types of blockchain have resisted the pressure to decrease their environmental impact, including Bitcoin, whose attributed 2021 annual emissions will produce emissions responsible for around 19,000 future deaths. …”
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403
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Published 2018“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”
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404
Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
Published 2018“…Our results show that HFD increased bone mineral density to a greater extent in KO mice than in WT mice without affecting the total body weight and fat mass. …”
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”
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407
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The association between tobacco use and COVID-19 in Qatar
Published 2022“…Our data suggests that only smokeless tobacco users may be at an increased risk for severe disease, yet this requires further investigation as other studies have reported smoking to be associated with an increased risk of greater disease severity.…”
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409
Exploring the Impacts of Artificial Intelligence (AI) Technology Implementation at the Individual and Team Levels_
Published 2023“…The public sector is under increasing pressure to deliver efficient services, attain high levels of customer satisfaction, and meeting the pressing societal needs. …”
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410
Iron slag/activated carbon-electrokinetic system with anolyte recycling for single and mixture heavy metals remediation
Published 2024“…The copper removal increased to 89.21 % when the anolyte solution was recycled to the cathode compartment. …”
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A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV
Published 2010“…Fabry disease is an X-linked lysosomal storage disorder that leads to abnormal accumulation of glycosphingolipids due to a deficiency of alpha-galactosidase A (AGAL). …”
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414
Breast cancer cells and bone marrow mesenchymal stromal cells
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415
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
Published 2024“…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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417
Expanding the donor pool
Published 2002“…In 1990, one-year graft survival rates were about 70%; by 2000, they were greater than 90% (United States Renal Data System, 2001). …”
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418
Exploring Ultra-Processed Foods: Impact on Satiety, Eating Patterns, Blood Glucose Levels and Food Addiction
Published 2025“…Results: Higher UPF intake was significantly associated with lower enjoyment of food (p = 0.002), greater food cravings (p = 0.003), and higher food addiction (FA) symptoms (p < 0.001). …”
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The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications
Published 2021“…<p dir="ltr">Diabetes mellitus is a major debilitating disease whose global incidence is progressively increasing with currently over 463 million adult sufferers and this figure will likely reach over 700 million by the year 2045. …”
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Rethinking (un)blinding in biomedical proposal peer review: A multi-stakeholder qualitative study
Published 2025“…These shortcomings highlight the need for greater openness in peer review and increased transparency in fund allocation processes.…”