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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…It is one of the deadliest cancer types since its mortality rate per year is nearly equal to its incidence rate. Therefore, there’s a need for more effective and selective therapeutic approaches for targeting PC. …”
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262
The Pros and Cons of Use of Handheld Electronic Devices During Ward Rounds and the Impact of the COVID-19 Pandemic
Published 2023“…The COVID-19 pandemic led to a decrease in the use of HEDs by both faculty [38(64%)] and PGTs [42(60%)].…”
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
Published 2020“…However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic agents against breast cancer need investigation.</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …”
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264
Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
Published 2024“…Findings suggest that sexual risk behavior was taking place during the pandemic despite the lockdowns and highlight the need to minimize disruptions in provision of SHS during similar crises, particularly to key populations.…”
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265
Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat.
Published 2005“…As a result of delayed gastricemptying, grapefruit and pineapple juices may moderate sharp increases in postprandial plasma TAG concentrationsaccompanying peak digestion and absorption.…”
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266
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008“…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …”
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267
A Scoping Review to Find Out Worldwide COVID-19 Vaccine Hesitancy and Its Underlying Determinants
Published 2021“…Sometimes, several studies had been performed in the same country, and it was observed that vaccine hesitancy was high earlier and decreased over time with the hope of vaccine efficacy. …”
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268
Business Continuity Management Maturity Model for Banks in UAE
Published 2008“…They are faced with increasing levels of global competition, demanding customers and employees, shrinking product lifecycles and decreasing acceptable response times (Lockamy & McCormack, 2004) They have employees and deal with clients, suppliers & vendors from all over the world. …”
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…Further studies are needed to assess the impact of these novel therapies on end-organ-specific complications of SCD.…”
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Raising awareness of menopause in Iran
Published 2021“…Women with one or two children had greater awareness than those with more than four. …”
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NON-WORK-RELATED FACTORS THAT INFLUENCE THE WORK COMMITMENT OF GENERATION Y UAE NATIONALS
Published 2021“…More so, the fact that neighbours appreciate roles that Generation Y play in the society increases commitment. Lastly, religiosity leads to greater commitment among Genera-tion Y to their organisations especially if the work matches their religious values. …”
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273
Direct assembly process
Published 2007“…In this paper the effect of diluent content of the IPT, electrode thickness, and composition were optimized in term of maximum peak strain and strain rate generated by an IPT. …”
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274
Performance analysis of a small-scale Orthopter-type Vertical Axis Wind Turbine
Published 2018“…Increasing solidity was achieved by either decreasing the blade aspect ratio or increasing the number of blades, both resulting in a higher peak power coefficient (Cp,max) of the VAWT. …”
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275
Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis
Published 2021“…</p><h3>Conclusions</h3><p dir="ltr">The challenges and concerns that impede the use of Patient Online seem to be of greater importance than the facilitators that encourage its use. …”
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Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing
Published 2022“…</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …”
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Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial
Published 2023“…Beyond 2-year trial follow-up, Markov model predicted a decrease in colectomy rate, but it remained slightly higher for ciclosporin. …”
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…These findings contribute to the growing understanding of nanoparticle toxicity profile and underscore the need for further research to ensure the safe application of nanoparticles in biomedical and other fields.…”
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The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity
Published 2024“…Our findings indicate that an increased representation of women on the board of directors is associated with greater independence among board members and a higher number of board members being hired. …”