-
361
Solubilization of Protein Aggregates by the Acid Stress Chaperones HdeA and HdeB
منشور في 2008"…HdeA, HdeB, and HdeA and HdeB together display an increasing efficiency for the solubilization of protein aggregates at pH 3. They are less efficient for the solubilization of aggregates at pH 2, whereas HdeB is the most efficient. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
362
Phenotypic and proteomic characterization of Dbr48, a candida albicans cell wall protein. (c2018)
منشور في 2018"…Our results showed that the heterozygous mutant strain exhibited a 10% decrease in adhesion mirrored by a 20% decrease in biofilm formation, and a slight sensitivity to oxidative stress agents and SDS. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
masterThesis -
363
Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
منشور في 2025"…While some real-world studies have reported a decrease in VOCs and hospitalizations, the results are inconsistent and not conclusive. …"
-
364
Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection
منشور في 2024"…(iv) Agents moving in the right way are rewarded with an increase in their associated transition probability, while the agents going in the wrong direction are discouraged with a decrease in their associated transition probabilities; this promotes the establishment of an equilibrium state and leads to convergence. …"
-
365
-
366
Performance comparison of different flow arrangements of 4-fluid internally-cooled liquid desiccant dehumidifiers
منشور في 2022"…The approximate difference between the best and poorest performing flow arrangements in terms of the decrease in supply air humidity ratio and enthalpy is 4.3% and 10.5%, respectively. …"
-
367
Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">The challenges and concerns that impede the use of Patient Online seem to be of greater importance than the facilitators that encourage its use. …"
-
368
Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing
منشور في 2022"…</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …"
-
369
Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
منشور في 2006"…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
370
Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
منشور في 2019"…Dedifferentiation is well characterized by the decrease in expression of key β cell markers such as genes encoding major transcription factors, e.g., MafA, NeuroD1, Nkx6.1, and Foxo1, and an increase in atypical or “disallowed” genes for β cells such as lactate dehydrogenase, monocarboxylate transporter MCT1, or progenitor cell genes (Neurog3, Pax4, or Sox9). …"
-
371
A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies
منشور في 2022"…Here we study the effect of electron irradiation on the electronic transport properties of aromatic 5,5′-bis(mercaptomethyl)-2,2′-bipyridine (BPD; HS-CH2-(C5H3N)2-CH2-SH) and electron saturated 1-dodecanethiol (C12; CH3-(CH2)11-SH) molecules self-assembled on an Au (111) surface. …"
-
372
The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity
منشور في 2024"…Our findings indicate that an increased representation of women on the board of directors is associated with greater independence among board members and a higher number of board members being hired. …"
-
373
Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study
منشور في 2023"…</p><h3>Conclusions</h3><p dir="ltr">This study found that patients who received a drain had longer hospital stays and greater blood loss and transfusion rates compared to those who did not. …"
-
374
An improved non-dimensional model of wet-cooling towers
منشور في 2020"…The first method shows a maximum decrease of 4.4 per cent in error, whereas in the second method, the maximum error was found to be 3.3 and 6.8 per cent when the inlet air was unsaturated and saturated, respectively. …"
احصل على النص الكامل
article -
375
Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials
منشور في 2023"…There were no significant differences between the two groups when assessing favorable neurological outcome (RR 1.01, 95% CI: 0.92 to 1.10; I2 = 4%), NSE at 48 h (MD 0.04, 95% CI: −0.67 to 0.76; I2 = 0%), and ICU length of stay (MD −2.86 days, 95% CI: −8.00 to 2.29 days; I2 = 0%).</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …"
-
376
Optimization of Electric Vehicles Wireless Charging
منشور في 2019احصل على النص الكامل
doctoralThesis -
377
The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
منشور في 2023"…Europe‘s aging population is increasing, affecting various sectors, including the healthcare system, labor market, and public services. …"
احصل على النص الكامل
-
378
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
منشور في 2017"…Sensitivity to HuArgI (Co)- PEG5000-induced arginine deprivation was attributable to the complete dependence on exogenous arginine of two of the five PC cell lines tested and to the partial arginine auxotrophy in combination with fast proliferative requirements of the remaining three cell lines. The lack of ASS-1 expression was demonstrated to be the underlying cause behind complete arginine dependence. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
masterThesis -
379
Impact of severe hypoglycemia on the heat shock and related protein response
منشور في 2021"…At baseline, MAPKAPK5 (p = 0.02) and UBE2G2 (p = 0.003) were elevated and STUB1 decreased (p = 0.007) in T2D. At hypoglycemia: PPP3CA (p < 0.03) was increased and EPHA2 (p = 0.01) reduced in T2D; by contrast, three proteins were reduced in controls [HSPA1A (p = 0.007), HSPB1 (p < 0.02), SMAD3 (p = 0.005)] while only MAPKAPK5 was elevated (p = 0.02). …"
-
380
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
منشور في 2021"…Together with artificial intelligence-driven in silico and in vitro screening, this C. elegans model identified five compounds that reduced motor dysfunction induced by α-synuclein. Three of these compounds also decreased α-synuclein oligomers in mammalian neurons, including rifabutin which has not been previously investigated for Parkinson’s disease. …"