Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

“…Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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Understanding the progress and challenges in the fields of thermo-catalysis and electro-catalysis for the CO₂ conversion to fuels by V. S. K. Yadav (17727660)

“…Generally, higher temperatures in thermo-catalytic process or electrical potentials in electrocatalytic process are used to increase the reaction rate to get the desired results and to overcome the kinetic barrier. Several studies have been reported in both the processes with a desire to decrease the atmospheric CO₂ concentration by stopping CO₂ emissions at the site of generation itself. …”

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…<div><p>FOXA2 has been known to play important roles in liver functions in rodents. …”

A Machine Learning Approach on Chest X-Rays for Pediatric Pneumonia Detection by Barakat, Natali Imad

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Notch Sensitivity of Fiber Reinforced Composite by Elyoussef, Mostafa

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Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection by Atiq ur Rehman (3044409)

“…(iv) Agents moving in the right way are rewarded with an increase in their associated transition probability, while the agents going in the wrong direction are discouraged with a decrease in their associated transition probabilities; this promotes the establishment of an equilibrium state and leads to convergence. …”

Performance comparison of different flow arrangements of 4-fluid internally-cooled liquid desiccant dehumidifiers by Ali Pakari (14158902)

“…The approximate difference between the best and poorest performing flow arrangements in terms of the decrease in supply air humidity ratio and enthalpy is 4.3% and 10.5%, respectively. …”

Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis by Alaa Abd-Alrazaq (17430900)

“…</p><h3>Conclusions</h3><p dir="ltr">The challenges and concerns that impede the use of Patient Online seem to be of greater importance than the facilitators that encourage its use. …”

Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing by Mohamad Saad (214545)

“…</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …”

Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia by Taher, Ali

“…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …”
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A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies by Y. Tong (18394389)

“…Here we study the effect of electron irradiation on the electronic transport properties of aromatic 5,5′-bis(mercaptomethyl)-2,2′-bipyridine (BPD; HS-CH2-(C5H3N)2-CH2-SH) and electron saturated 1-dodecanethiol (C12; CH3-(CH2)11-SH) molecules self-assembled on an Au (111) surface. …”

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil Shallik (15900256)

“…In such cases of severe illness, high flow nasal oxygen (HFNO) has been used to provide oxygenation to COVID-19 patients. …”

The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity by Robert Gharios (21393863)

“…Our findings indicate that an increased representation of women on the board of directors is associated with greater independence among board members and a higher number of board members being hired. …”

Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study by Anas Albasha (17765964)

“…</p><h3>Conclusions</h3><p dir="ltr">This study found that patients who received a drain had longer hospital stays and greater blood loss and transfusion rates compared to those who did not. …”

Strengthening of thin reinforced concrete slabs with CFRP laminates by Hawileh, Rami

“…Over the years, engineers and researchers have been working continuously to reduce the dead loads on buildings by reducing the sizes of structural elements. …”
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An improved non-dimensional model of wet-cooling towers by QURESHI, BILAL AHMED

“…The first method shows a maximum decrease of 4.4 per cent in error, whereas in the second method, the maximum error was found to be 3.3 and 6.8 per cent when the inlet air was unsaturated and saturated, respectively. …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials by Huzaifa Ahmad Cheema (16328980)

“…There were no significant differences between the two groups when assessing favorable neurological outcome (RR 1.01, 95% CI: 0.92 to 1.10; I2 = 4%), NSE at 48 h (MD 0.04, 95% CI: −0.67 to 0.76; I2 = 0%), and ICU length of stay (MD −2.86 days, 95% CI: −8.00 to 2.29 days; I2 = 0%).</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”

The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe by Ammari, Lora

“…Europe‘s aging population is increasing, affecting various sectors, including the healthcare system, labor market, and public services. …”
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) by Khalil, Nathalie

“…Sensitivity to HuArgI (Co)- PEG5000-induced arginine deprivation was attributable to the complete dependence on exogenous arginine of two of the five PC cell lines tested and to the partial arginine auxotrophy in combination with fast proliferative requirements of the remaining three cell lines. The lack of ASS-1 expression was demonstrated to be the underlying cause behind complete arginine dependence. …”
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Impact of severe hypoglycemia on the heat shock and related protein response by Alexander S. Atkin (18520107)

“…At baseline, MAPKAPK5 (p = 0.02) and UBE2G2 (p = 0.003) were elevated and STUB1 decreased (p = 0.007) in T2D. At hypoglycemia: PPP3CA (p < 0.03) was increased and EPHA2 (p = 0.01) reduced in T2D; by contrast, three proteins were reduced in controls [HSPA1A (p = 0.007), HSPB1 (p < 0.02), SMAD3 (p = 0.005)] while only MAPKAPK5 was elevated (p = 0.02). …”