Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

“…While some real-world studies have reported a decrease in VOCs and hospitalizations, the results are inconsistent and not conclusive. …”

Performance comparison of different flow arrangements of 4-fluid internally-cooled liquid desiccant dehumidifiers by Ali Pakari (14158902)

“…The approximate difference between the best and poorest performing flow arrangements in terms of the decrease in supply air humidity ratio and enthalpy is 4.3% and 10.5%, respectively. …”

Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis by Alaa Abd-Alrazaq (17430900)

“…</p><h3>Conclusions</h3><p dir="ltr">The challenges and concerns that impede the use of Patient Online seem to be of greater importance than the facilitators that encourage its use. …”

Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing by Mohamad Saad (214545)

“…</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …”

Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia by Taher, Ali

“…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …”
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Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes by Abu Saleh Md Moin (6189512)

“…Dedifferentiation is well characterized by the decrease in expression of key β cell markers such as genes encoding major transcription factors, e.g., MafA, NeuroD1, Nkx6.1, and Foxo1, and an increase in atypical or “disallowed” genes for β cells such as lactate dehydrogenase, monocarboxylate transporter MCT1, or progenitor cell genes (Neurog3, Pax4, or Sox9). …”

A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies by Y. Tong (18394389)

“…Here we study the effect of electron irradiation on the electronic transport properties of aromatic 5,5′-bis(mercaptomethyl)-2,2′-bipyridine (BPD; HS-CH2-(C5H3N)2-CH2-SH) and electron saturated 1-dodecanethiol (C12; CH3-(CH2)11-SH) molecules self-assembled on an Au (111) surface. …”

Using a Cavitation Model to Represent the Acoustic Release Kinetics from Folated Micelles by Tanbour, Rafeeq Kamal

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The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity by Robert Gharios (21393863)

“…Our findings indicate that an increased representation of women on the board of directors is associated with greater independence among board members and a higher number of board members being hired. …”

Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study by Anas Albasha (17765964)

“…</p><h3>Conclusions</h3><p dir="ltr">This study found that patients who received a drain had longer hospital stays and greater blood loss and transfusion rates compared to those who did not. …”

An improved non-dimensional model of wet-cooling towers by QURESHI, BILAL AHMED

“…The first method shows a maximum decrease of 4.4 per cent in error, whereas in the second method, the maximum error was found to be 3.3 and 6.8 per cent when the inlet air was unsaturated and saturated, respectively. …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials by Huzaifa Ahmad Cheema (16328980)

“…There were no significant differences between the two groups when assessing favorable neurological outcome (RR 1.01, 95% CI: 0.92 to 1.10; I2 = 4%), NSE at 48 h (MD 0.04, 95% CI: −0.67 to 0.76; I2 = 0%), and ICU length of stay (MD −2.86 days, 95% CI: −8.00 to 2.29 days; I2 = 0%).</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”

Impact of severe hypoglycemia on the heat shock and related protein response by Alexander S. Atkin (18520107)

“…At baseline, MAPKAPK5 (p = 0.02) and UBE2G2 (p = 0.003) were elevated and STUB1 decreased (p = 0.007) in T2D. At hypoglycemia: PPP3CA (p < 0.03) was increased and EPHA2 (p = 0.01) reduced in T2D; by contrast, three proteins were reduced in controls [HSPA1A (p = 0.007), HSPB1 (p < 0.02), SMAD3 (p = 0.005)] while only MAPKAPK5 was elevated (p = 0.02). …”

The Role of Cdc42 and the Cross-talk with RhoA/RhoC during Invadopodia Formation and Invasion in Glioblastoma Multiforme by Maalouf, Hiba

“…In this study, we sought to investigate the role of these three Rho GTPases in 3D migration, particularly in the formation of invadopodia which are the actin rich structures required for the degradation of the extracellular matrix. …”
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The risk of chromium picolinate supplementation in normolipidemic rats fed regular or high fat diet. (c2005) by Bou Farah, Helena

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Studies on Natural Extracts as Inhibitors of Mild Steel Corrosion in 1M HC1 Solution by Shanableh, Alaa

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Effect of chronic and non-chronic moderate wine consumption upon rat lipoprotein profile in the blood. (c2002) by Slaiby, Rita

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Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases by Pawlik, Timothy

“…Adverse preoperative biologic factors including tumor number greater than 3 (P = 0.01) and a preoperative CEA level greater than 200 ng/mL (P = 0.04) were associated with an increased risk of positive surgical margin. …”
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MRP4 by Abi-Gerges, Aniella

“…Application of ISO (1nM) induced a similar increase in cAMP level in WT and MRP4 KO mice (YFP/CFP: 4.4 ± 0.15 in WT vs 4.1 ± 0.44 in KO cells), whereas cAMP signal was greater in MRP4 KO compared to WT mice after PDE inhibition by IBMX (ISO 1nM + IBMX 300µM: 8.1 ± 0.6 in WT vs 11.8 ± 0.62 in KO cells; p<0.01). …”
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The Islamist groups in Tripoli. (c2008) by Abbas, Nivine H.

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