Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

“…Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
Get full text
Get full text
Get full text

Understanding the progress and challenges in the fields of thermo-catalysis and electro-catalysis for the CO₂ conversion to fuels by V. S. K. Yadav (17727660)

“…Generally, higher temperatures in thermo-catalytic process or electrical potentials in electrocatalytic process are used to increase the reaction rate to get the desired results and to overcome the kinetic barrier. Several studies have been reported in both the processes with a desire to decrease the atmospheric CO₂ concentration by stopping CO₂ emissions at the site of generation itself. …”

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…Cytokines, including interferon γ (IFNγ), tumor necrosis factor α (TNFα) and interleukin-6 (IL-6), and their downstream effectors such as Signal Transducer and Activator of Transcription 3 (STAT3), have been shown to play a prominent role in muscle wasting. …”

Children safety risk factors in Khorasan Razavi province by Ali Zayerzadeh (19774491)

“…<p dir="ltr">Although there has been a decline in the popularity of walking, it remains a very commonly employed mode of travel and people of almost all ages and sexes walk. …”

Food purchase and eating behavior during the COVID-19 pandemic: A cross-sectional survey of Russian adults by Tarek Ben Hassen (15742605)

“…The results reveal that diet and food shopping, preparation, and use have been widely affected. Indeed, the survey results suggested (i) a change in the modality of acquiring food, consumers reduced the number of shopping trips and buying more on each trip to minimize store visits; (ii) a surge of stockpiling of non-perishable food items; (iii) a shift toward healthier diets; (iv) an increase in culinary capabilities; (v) a decrease of food waste. …”

Effect of anions on the structural, morphological and dielectric properties of hydrothermally synthesized hydroxyapatite nanoparticles by Lakshmanaperumal Sundarabharathi (14152482)

“…<h2>Abstract</h2><p dir="ltr">Synthetic nano hydroxyapatites (HA) have been considered as potential biomaterials for bone tissue engineering applications because of its excellent biological properties. …”

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…<div><p>FOXA2 has been known to play important roles in liver functions in rodents. …”

Khalasa date palm leaf fiber as a potential reinforcement for polymeric composite materials by Elsadig Mahdi (9967349)

“…Thermogravimetric analysis has been used to examine the thermal stability of KDPLF. …”

Energy-Efficient Cell Association and Load Balancing for Low Battery Users in Heterogeneous Cellular Networks by Abdul Qadeer Khan (22502168)

“…Results on cell association, load balancing, and EE of LBUs have been compared with conventional association schemes. …”

A Machine Learning Approach on Chest X-Rays for Pediatric Pneumonia Detection by Barakat, Natali Imad

Get full text

Notch Sensitivity of Fiber Reinforced Composite by Elyoussef, Mostafa

Get full text

Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis by Alaa Abd-Alrazaq (17430900)

“…</p><h3>Conclusions</h3><p dir="ltr">The challenges and concerns that impede the use of Patient Online seem to be of greater importance than the facilitators that encourage its use. …”

Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing by Mohamad Saad (214545)

“…</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …”

Efficiency of Azithromycin-Loaded Lipid Polymer Hybrid Nano-vehicle as a Repurposing formulation in Colon Cancer Management by Tarraf, Vanessa

“…It displayed a safe profile on HT29 cell line, with the coated formulation having the lowest IC50= 24.17 μM at 24 hours that even decreases at longer time intervals, which confirms its potential for colorectal cancer management.…”
Get full text
Get full text
Get full text

Graph-Guided Regularized Regression of Pacific Ocean Climate Variables to Increase Predictive Skill of Southwestern U.S. Winter Precipitation by Tejedor, Alejandro

“…Physics-based deterministic models show limited ability to predict precipitation as the lead time increases, due to imperfect representation of physical processes and incomplete knowledge of initial conditions. …”
Get full text

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 by Joan B Soriano (6458528)

“…Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578–4 044 819) in 2017, an increase of 18·0% since 1990, while total DALYs increased by 13·3%. …”

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Ex vivo incubation of LAT2KO muscle with rapamycin recovered proteolysis function, demonstrating a mTORC1‐dependent pathway. Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”

The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity by Robert Gharios (21393863)

“…Our findings indicate that an increased representation of women on the board of directors is associated with greater independence among board members and a higher number of board members being hired. …”

Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study by Anas Albasha (17765964)

“…</p><h3>Conclusions</h3><p dir="ltr">This study found that patients who received a drain had longer hospital stays and greater blood loss and transfusion rates compared to those who did not. …”

The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe by Ammari, Lora

“…Europe‘s aging population is increasing, affecting various sectors, including the healthcare system, labor market, and public services. …”
Get full text