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681
mTORC1 loss impairs epidermal adhesion via TGF-b/Rho kinase activation
منشور في 2017"…Despite its central position in oncogenic intracellular signaling networks, the role of mTORC1 in epithelial development has not been studied extensively in vivo. Here, we have used the epidermis as a model system to elucidate the cellular effects and signaling feedback sequelae of mTORC1 loss of function in epithelial tissue. …"
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article -
682
Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
منشور في 2010"…Ultrasound (US) increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, US was used to deliver doxorubicin (Dox) sequestered in micelles in an in vivo rat model with bilateral leg tumors. …"
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article -
683
Oxandrolone Treatment in Adults with Severe Thermal Injury
منشور في 2009"…Oxandrolone, a synthetic derivative of testosterone, has been used in adult patients with severe thermal injury to enhance lean body mass accretion, restore body weight, and accelerate wound healing. …"
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article -
684
α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain
منشور في 2022"…In the hippocampus, aKG increases BDNF levels possibly through the PGC1a-BDNF pathway. In the NAc, aKG decreases BDNF levels possibly through the FNDC5-BDNF pathway.…"
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masterThesis -
685
Reduced graphene aerogels as energy efficient selective oil sorbents
منشور في 2022"…The presence of H<sub>2</sub> significantly decreased the oxygen-containing functional groups in graphene aerogel. …"
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686
Conflict in Ukraine and the unsettling ripples: implications on food systems and development in North Africa
منشور في 2024"…The findings indicate that food systems in North Africa have been particularly affected by the conflict in Ukraine, owing to its influence on the global economy, trade dynamics, and food prices. …"
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687
The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms
منشور في 2025"…While the incidence and mortality of CRC have decreased overall due to better screening, rates in adults under 50 have risen. …"
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688
Hypertension in Childhood Nephrotic Syndrome
منشور في 2019"…Others are associated with chronic and more sustained HTN such as renal fibrosis, decreased GFR, and progression of chronic kidney disease. …"
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689
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
منشور في 2023"…However, the effect of a rib and elastic plate on the acoustic properties of a channel for a wide range of Reynolds numbers has not yet been investigated, although their use could reduce noise pollution. …"
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690
To What Extent is Humanistic Language Teaching Incorporated in the Instructional Practices of the Foundation Teachers in Higher Colleges of Technology (HCT)-Fujairah, UAE? A Case S...
منشور في 2014"…The participants were also convinced that incorporating HLT in the Foundation context was beneficial to learners as it decreased learning anxiety and helped them become more engaged in learning. …"
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691
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
منشور في 2023"…<p dir="ltr">Several pathways and/or genes have been shown to be dysregulated in obesity-induced insulin resistance (IR) and type 2 diabetes (T2D). …"
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692
Genotypic and phenotypic characterization of Candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin
منشور في 2019"…Caspofungin sensitive strains showed decreased resistance to Congo red yet increased virulence and biofilm formation. …"
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article -
693
LDL-C Targets in Secondary Prevention: How Low Should We Go?
منشور في 2019"…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …"
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694
Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration
منشور في 2009"…Cerebral drug transport by ABC transporters in MPTP models has never been reported. Methods: We have investigated the transport of bromocriptine through the blood-brain barrier (BBB) in a MPTP model to understand the influence of the dopaminergic degeneration on ABCB1 and ABCG2. …"
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article -
695
In-Vitro Degradation of Hollow Silica Reinforced Magnesium Syntactic Foams in Different Simulated Body Fluids for Biomedical Applications
منشور في 2020"…Further, the effect of corrosive environment on the degradation behaviour of Mg has been elucidated.…"
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article -
696
RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells
منشور في 2019"…The role of the RHO family GTPase RHOG in angiogenesis in vascular endothelial cells has recently been elucidated. However, the regulation of RHOG during this process, as well as its cross-talk with other RHO GTPases, have yet to be fully examined. …"
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article -
697
Determinants of dividend payout ratio
منشور في 2014"…Moreover, the study uses the homogeneous subcategory within the purposive sampling since only similar firms in construction industry had been examined. The outcome of the study provides a vital insight into the determinants of dividends payout ratio of companies in MENA region. …"
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conferenceObject -
698
Simulation of the size-composition distribution of atmospheric nanoparticles over Europe
منشور في 2018"…<p dir="ltr">PMCAMx-UF, a three-dimensional chemical transport model focusing on the simulation of the ultrafine particle size distribution and composition has been extended with the addition of the volatility basis set (VBS) approach for the simulation of organic aerosol (OA). …"
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699
Non-Isolated DC–DC Power Converter With High Gain and Inverting Capability
منشور في 2021"…The parasitic of the components has been considered in the analysis to show the deviation from the ideal cases. …"
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700
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
منشور في 2018"…EBV is highly prevalent since it affects more than 90% of individuals worldwide and has been linked to several malignancies including PTLDs, which are one of the most common malignancies following transplantation. …"