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841
The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
Published 2022“…This was accompanied by an increase in estradiol levels by 14.9 pmol/L (<i>p</i> < 0.0001), and decreases in progesterone (0.2 ng/mL, <i>p</i> < 0.0001), LH (10.4 U/L, <i>p</i> < 0.0001) and FSH (8.4 U/L, <i>p</i> < 0.0001) were demonstrated at 12-years. …”
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842
Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity
Published 2020“…In vitro studies indicated scFvs inhibit the seeding of α-syn aggregation in a time-dependent manner, decreased α-syn seed-induced toxicity in a cell model of PD, and reduced the production of insoluble α-syn phosphorylated at Ser-129 (pS129-α-syn). …”
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843
Comparing WZB117-liposome Synthesis via Thin-film Hydration and Microfluidic Methods
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844
From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
Published 2025“…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …”
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845
COVID-19 may have increased global support for universal health coverage: multi-country observational study
Published 2023“…Trust in the government to deal with COVID-19 decreased over time, and this negative trajectory predicted a demand for better future government intervention in healthcare (ß = −0.10, <i>p</i> = 0.0003).…”
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846
The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort
Published 2019“…Specific CFO-related running mechanical adjustments included a reduced braking impulse occurring in the first 25% of contact time with EVA, whereas wearing TPU increased propulsive loading rate.…”
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847
Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish
Published 2019“…It enables practical real time visualization in a non-invasive manner, making the modality especially useful to image dynamic cardiac structures. …”
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848
An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH<sub>4</sub>-CO<sub>2</sub>-H<sub>2</sub>S
Published 2021“…Overall, it was found that separation of CO<sub>2</sub> in solid phase improves when increasing the operating pressure up to 20 bar, and decreases at higher temperatures. Similarly, the separation of H<sub>2</sub>S in either liquid or solid phase improves at higher pressures and lower temperatures. …”
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849
Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
Published 2024“…Cortical bone, however, was decreased in young mice on CR and remained reduced in aged mice, irrespective of dietary intervention. …”
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850
Past and future climate effects on population structure and diversity of North Pacific surfgrasses
Published 2024“…Genetic diversity of <i>Phyllospadix torreyi </i>decreases from north to south, but in <i>Phyllospadix scouleri</i> the trend is variable. …”
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851
Tailoring the deposition of MoSe<sub>2</sub> on TiO<sub>2</sub> nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting
Published 2023“…The photoelectrochemical properties of the heterojunction were explored and optimized as a function of the thickness of the MoSe<sub>2</sub> layer, which was controlled by the sputtering time. The MoSe<sub>2</sub> grows perpendicularly on TiO<sub>2</sub> NRs in a 2D layered structure, maximizing the exposed active edges, an essential aspect that permits maximum exploitation of deposited MoSe<sub>2</sub>. …”
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852
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853
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. …”
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854
Glycemic outcomes of Advanced Hybrid Closed Loop system in children and adolescents with Type 1 Diabetes, previously treated with Multiple Daily Injections (MiniMed 780G system in...
Published 2022“…The primary outcome of the study was the change in the time spent in the target in range (TIR) of 70–180 mg/dl and HbA1c from baseline (MDI + CGM, 1 week) to study phase (AHCL, 12 weeks). …”
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855
New media and new practices of exploitation
Published 2015“…Employees might be categorized in four different groups: Regular, contracted, part time and freelancer. These categories might be observed both in big media companies and boutique media initiatives at the same time However, there is a new and rising category which is not contracted and highly exploited: Prosumers. …”
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856
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2021“…<h3>Background</h3><p dir="ltr">Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally.…”
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857
Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2022“…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …”