Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells by Ejlal Abu-El-Rub (5168183)

“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”

The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties by Jelena Eric (21015107)

“…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …”

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …”

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy by Jia-Zhen Wu (6844793)

“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”

Old subjects with sepsis in the emergency department: trend analysis of case fatality rate by Andrea Fabbri (356760)

“…Along the years CFR decreased from 31.8% (2009–2010) to 25.0% (2015–2016); P = 0.007. …”

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: eLife<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.7554/elife.31511" target="_blank">https://dx.doi.org/10.7554/elife.31511</a></p>…”

Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

“…Conversely, the peptide inhibitor restores endolysosomal function and thereby decreases α-synuclein levels in multiple models, including female and male human cells harboring disease-causing α-synuclein mutations. …”

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy by Ajaz A. Bhat (12984701)

“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Molecular Cancer<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12943-020-01294-3" target="_blank">https://dx.doi.org/10.1186/s12943-020-01294-3</a></p>…”

Advanced direct air capture of CO₂ using air conditioning systems: a life cycle assessment by Namra Mir (17017734)

“…These reductions are attributed to decreased electricity requirements achieved via system synergies. …”

Tranexamic Acid Application in Facial Aesthetic Surgery: An Umbrella Review by Mohamed Badie Ahmed (10223510)

“…While in the case of septorhinoplasty, 3 studies revealed that TXA use decreased BLV. Moreover, in the case of rhytidectomy, 3 out of 6 systematic reviews showed reduction in BLV, while 2 reported reductions in DOS. …”

Visible Light Photocatalytic Activity of Ag/WO₃ Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark by Maha Matalkeh (17148358)

“…Ultraviolet–visible spectra analysis observed a large redshift in the absorbing band edge and decreased bandgap energy from 2.6 to 2.1 eV. Photocatalytic analysis at different concentrations of 1% Ag/WO₃ under visible light indicated a high degradation efficiency. …”

Epidemiological and clinical characteristics of fall-related injuries: a retrospective study by Ahammed Mekkodathil (4578838)

“…Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …”

Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis by Osama Hussein (21301202)

“…In ACG patients, medication use decreased by 67.13% at 12 months and 51.58% at 24 months (<i>p</i> < 0.001 for both), while in OAG patients, the reduction was 45.52% at 12 months and 50.19% at 24 months (<i>p</i> < 0.001). …”

‘The newest vital sign among pregnant women attending women wellness and research Centre in Qatar: a cross-sectional study’ by Sarah Naja (9954737)

“…</p><h2>Other Information</h2> <p> Published in: BMC Pregnancy and Childbirth<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1186/s12884-021-03542-w" target="_blank">http://dx.doi.org/10.1186/s12884-021-03542-w</a></p>…”

Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS by Anna Halama (545988)

“…IS was lower in PCOS (p < 0.001) and was further decreased by the lipid infusion in both PCOS and controls. …”

Part II.: Dissimilar friction stir welding of nickel titanium shape memory alloy to stainless steel – microstructure, mechanical and corrosion behavior by Parker West (17268946)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Advanced Joining Processes<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jajp.2021.100072" target="_blank">https://dx.doi.org/10.1016/j.jajp.2021.100072</a></p>…”

Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy by Olfa Khalifa (10914452)

“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Biomedicines<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/biomedicines10102652" target="_blank">https://dx.doi.org/10.3390/biomedicines10102652</a></p>…”

Recyclable polyaspartate-coated magnetic nanoparticles for sustainable control of calcite and barite scales in oilfield operations by Abdelrahman T. Abdelaal (14674629)

“…<p dir="ltr">Scale formation is a major challenge in hydrocarbon production, leading to decreased efficiency, equipment damage, and increased operational costs. …”

A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge by Salim Al Lahham (16515333)

“…</p><h3>Methods</h3><p dir="ltr">This is a case series that includes 9 patients where we describe a technique that has the potential to enhance the survival of the first dorsal metacarpal artery (FDMA) flap and decreases the rate of distal necrosis via addition of a 5-mm skin bridge to the pedicle and by avoiding tunneling. …”

Microwave-Assisted Solvothermal Synthesis of Mo-Doped TiO₂ with Exceptional Textural Properties and Superior Adsorption Kinetics by Yahia H. Ahmad (14340210)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: Nanomaterials<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/nano12122051" target="_blank">https://dx.doi.org/10.3390/nano12122051</a></p>…”