Showing 1 - 20 results of 2,491 for search '(( hla ((e decrease) OR (we decrease)) ) OR ( i ((larger decrease) OR (marked decrease)) ))', query time: 0.59s Refine Results
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    All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

    Published 2024
    “…Understanding how membrane composition influences the dynamics and function of transmembrane proteins is crucial for the comprehensive elucidation of cellular signaling mechanisms and the development of targeted therapeutics. In this study, we employed all-atom molecular dynamics simulations to investigate the impact of different membrane compositions on the conformational dynamics of the NKG2A/CD94/HLA-E immune receptor complex, a key negative regulator of natural killer cell cytotoxic activity. …”
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    S1 File - by Hongyu Li (1332669)

    Published 2025
    “…Following the overexpression of miRNA 221 in myocardium, there was a marked alleviation of myocardial injury and cardiomyocyte apoptosis and necrosis, significant enhancement of left ventricular systolic function, and marked decrease in the levels of PLB, p-PLB (Ser16), p-PLB (Thr17), caspase 3 and Cyt C, as well as a significant decrease in total calcium levels in myocardium.…”
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    Biases in larger populations. by Sander W. Keemink (21253563)

    Published 2025
    “…Threshold parameter <i>c</i> = − 0 . 1 for the rectified cosine tuning with 4 neurons, and width <i>w</i> was 1 for von Mises tuning. …”
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