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large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
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How Do Molecular Crowders Influence Ligand Binding Kinetics with G‑Quadruplex DNA? The Role of Bound Water
Published 2025“…Understanding the kinetics of ligand interaction with G-quadruplex DNA (GqDNA) in a crowded cell-like environment is of paramount importance in biology and pharmacology, as it elucidates the effect of molecular crowders on reaction rates governing these interactionsa process that largely remains unexplored. …”
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How Do Molecular Crowders Influence Ligand Binding Kinetics with G‑Quadruplex DNA? The Role of Bound Water
Published 2025“…Understanding the kinetics of ligand interaction with G-quadruplex DNA (GqDNA) in a crowded cell-like environment is of paramount importance in biology and pharmacology, as it elucidates the effect of molecular crowders on reaction rates governing these interactionsa process that largely remains unexplored. …”
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<b>Human disturbance alters the foraging and spatiotemporal activity of a large carnivore</b>
Published 2025“…Responses to human disturbance were generally consistent across sites, with pumas adjusting their temporal, spatial, and foraging axes to decrease encounters with humans. Our results suggest that human-disturbed landscapes across regions alter the primary niche axes of pumas to construct a new realized niche in human landscapes, which may have important consequences for their ecological interactions and the functional role of this large carnivore.…”
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Overview of the parameters used in the model.
Published 2024“…<div><p>Background</p><p>Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the <i>Aedes albopictus</i> mosquito and global climate change, pose a significant threat to public health. Our study evaluates the effectiveness of emergency vaccination using a dynamic disease transmission model for a potential large-scale outbreak in Rome, Italy.…”