S1 File - by Hongyu Li (1332669)

“…Following the overexpression of miRNA 221 in myocardium, there was a marked alleviation of myocardial injury and cardiomyocyte apoptosis and necrosis, significant enhancement of left ventricular systolic function, and marked decrease in the levels of PLB, p-PLB (Ser16), p-PLB (Thr17), caspase 3 and Cyt C, as well as a significant decrease in total calcium levels in myocardium.…”

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). by Juan-Juan Xu (18590868)

(A) Auxiliary marking points to ensure complete and accurate seating of the prosthesis. by Long Li (6555)

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Macrophage-specific IGF-1 overexpression decreases plaque MMP8 and. by Patricia Snarski (22305205)

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Effects of GJE extract treatment decreased accumulation of Col1a1. by Natnicha Suttawong (22367172)

The heart rate was similar among the groups. by Hongyu Li (1332669)

“…Following the overexpression of miRNA 221 in myocardium, there was a marked alleviation of myocardial injury and cardiomyocyte apoptosis and necrosis, significant enhancement of left ventricular systolic function, and marked decrease in the levels of PLB, p-PLB (Ser16), p-PLB (Thr17), caspase 3 and Cyt C, as well as a significant decrease in total calcium levels in myocardium.…”

Primer sequences for RT-qPCR. by Hongyu Li (1332669)

“…Following the overexpression of miRNA 221 in myocardium, there was a marked alleviation of myocardial injury and cardiomyocyte apoptosis and necrosis, significant enhancement of left ventricular systolic function, and marked decrease in the levels of PLB, p-PLB (Ser16), p-PLB (Thr17), caspase 3 and Cyt C, as well as a significant decrease in total calcium levels in myocardium.…”

Altered expression of genes related to Ca²⁺ cycling or myocardial contraction. by Hongyu Li (1332669)

miRNA 221 improved left ventricular contractile function in MIRI mice. by Hongyu Li (1332669)

miRNA 221 alleviated calcium overload in myocardium and inhibited the expression of apoptosis-related genes in MIRI mice. by Hongyu Li (1332669)

miRNA 221 alleviated myocardial injury and inhibited apoptosis and necrosis of cardiac cells in MIRI mice. by Hongyu Li (1332669)

Blocking IFNAR leads to enhancement of IL-1β and IL-17 production. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

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Eggs jointly coordinate a caspase-1 and caspase-8 dependent pyroptotic cell death. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

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related to Fig 5. (A) the total number of eggs in the livers did not differ between BL/6 and Gsdmd-/- mice. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

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Anti-SjLLPi1 antibody treatment decreases worm burden in mice 7 days after <i>S. japonicum</i> infection. by Fanyan Chen (3909178)

related to Fig 3. (A) Live eggs induce AIM2 pyroptosome formation. Microscopy of AIM2-citrine macrophages stimulated with live eggs for 48 h. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

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Egg-induced IL-1β and IL-17 production is dependent on both Caspase-1 and Caspase-8. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

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The loss of NLRP3 and AIM2 results in reduced Th17 and enhanced Th2 cytokine responses. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

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Gsdmd deficiency reduces myeloid cell recruitment to the liver during schistosome infection. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

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related to Fig 4. ROS, K+ efflux and cathepsin B do not affect TNFα production in response to eggs. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

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