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181
Diagnosing type 2 diabetes using Hemoglobin A1c: a systematic review and meta-analysis of the diagnostic cutpoint based on microvascular complications
منشور في 2020"…</p><h3>Conclusions</h3><p dir="ltr">The prevalence of nephropathy and moderate retinopathy was increased in subjects with HbA1c values ≥ 6.5% confirming the high specificity of this value for diagnosing T2DM; however, at HbA1c < 6.5% retinopathy increased at age > 55 years and, most strikingly, in African-Americans, suggesting there may be excess microvascular complication prevalence (particularly nephropathy) in individuals below the diabetes diagnostic threshold.…"
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182
Immunoprofile of childhood diabetes
منشور في 2023"…When transcriptomic data was interrogated, an imbalance between ITGA4/ ITGB1 was observed in all groups where CD49d showed increased expression. Associated with these findings, anti-inflammatory Treg cytokines including IL-10 were decreased in T2D patients and elevated plasma levels of IL-17, which contributes to the insulin resistance and inflammation were observed.…"
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183
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…Moreover, MALAT1 knockdown dramatically suppressed oleic-induced lipid accumulation in HepG2 cells. Interestingly, knocking down MALAT1 significantly reduces the expression of CD36 in steatosis HepG2 cells in the presence of Ex-4. …"
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184
The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells
منشور في 2020"…Western blot analysis on MDA-MB-231 cells treated with C3 showed a significant increase in BAX/Bcl2 ratio with no significant effect on Pro-caspase-3 expression. …"
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185
Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes
منشور في 2021"…Partial correlation showed significant correlation between C4 with serum alanine aminotransferase (ALT) (p<0.05) and 2nd term diastolic blood pressure (p<0.05); Factor-H and C-reactive protein (CRP; p<0.05). …"
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186
It is not the same green: A comparative LCA study of green hydrogen supply network pathways
منشور في 2025"…<p dir="ltr">Green hydrogen (H<sub>2</sub>), a promising clean energy source garnering increasing attention worldwide, can be derived through various pathways, resulting in differing levels of greenhouse gas emissions. …"
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187
The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells
منشور في 2021"…It also significantly increased Bax/Bcl2 ratio and PERK levels without affecting caspase-3 expression. …"
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Tackling diabetes through lifestyle changes
منشور في 2015"…Type II diabetes mellitus (DM) is a lifelong condition that causes dangerously high blood sugar levels. …"
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190
Development of flexible PVDF/ BaTiO<sub>3</sub>-MoS<sub>2</sub> polymer nanocomposites for energy harvesting and gas sensing applications
منشور في 2024"…It was found that, compared to all other samples, the composite PVDF/BaTiO<sub>3</sub>–MoS<sub>2</sub> films had a high level of sensitivity. …"
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191
Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in healthy control and polycystic ovary syndrome women following chronic exercise training
منشور في 2022"…</p> <h2>Results</h2> <p>Intralipids dramatically increased CTRP-2 levels in PCOS (P = 0.02) and control (P = 0.004) subjects, which was not affected by insulin infusion or by exercise. …"
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192
Phase 1 and 2 Studies Demonstrate the Safety and Efficacy of Intraprostatic Injection of PRX302 for the Targeted Treatment of Lower Urinary Tract Symptoms Secondary to Benign Prost...
منشور في 2011"…Phase 1 subjects received increasing concentrations of PRX302 at a fixed volume; phase 2 subjects received increasing volumes per deposit at a fixed concentration. …"
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193
Assessment of tropospheric NO<sub>2</sub> concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202...
منشور في 2024"…Results also showed an increase in NO<sub>2</sub> levels during winter compared to that in summer, with wind speed being an important determining factor. …"
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194
Aerosol Optical Thickness over Large Urban Environments of the Arabian Peninsula—Speciation, Variability, and Distributions
منشور في 2019"…Reductions in local urban emissions are still considered to be efficient measures to improve air quality in these population centers despite the significant contribution of desert dust in the total particulate matter levels in the region.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Atmosphere<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/atmos10050228" target="_blank">https://dx.doi.org/10.3390/atmos10050228</a></p>…"
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195
D-Dimer, Fibrinogen, and IL-6 in COVID-19 Patients with Suspected Venous Thromboembolism: A Narrative Review
منشور في 2020"…In contrast, late presentations show evidence of prolonged pro thrombin time (PT) and activated partial thromboplastin (aPTT), increased platelets, and fibrinogen levels. Diagnosis and monitoring of disease progression are done by regular screening of laboratory parameters, including D-dimer and fibrinogen. …"
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196
Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype...
منشور في 2023"…Among the 835 proteins, two showed differential responsiveness to insulin; ATP5F1 protein was decreased, and MYLK2 was higher in the LIS group compared with that in the HIS group. …"
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197
Biomarkers of COVID-19 severity may not serve patients with polycystic ovary syndrome
منشور في 2021"…These identified pathways were complementary to another recent study comparing COVID-19 disease and control subjects, where proteomic panels also identified biological pathways involved in platelet degranulation and the coagulation cascade [2]. Whilst the comparison with absolute disease-free normality is relevant, an increasing proportion of the population have insulin resistant states with associated metabolic conditions; an example of such a metabolic condition is polycystic ovary syndrome (PCOS) where it has been shown that protein expression patterns may differ compared to those without PCOS [3]. …"
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198
Metabolic profiling of pre-gestational and gestational diabetes mellitus identifies novel predictors of pre-term delivery
منشور في 2020"…<h3>Background</h3><p dir="ltr">Pregnant women with gestational diabetes mellitus (GDM) or type 2 diabetes mellitus (T2DM) are at increased risks of pre-term labor, hypertension and preeclampsia. …"
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COVID-19 Severity in Patients With Apical Periodontitis: A Case Control Study
منشور في 2024"…</p><h3>Results</h3><p dir="ltr">COVID-19 complications were found to be associated with the presence of apical periodontitis (adjusted odds ratio = 2.72; 95% CI, 1.30–5.68; <i>P </i>= .008). Blood analyses revealed that COVID-19 patients with apical periodontitis had higher levels of white blood cells and <u>haemoglobin A1c </u>than the patients without apical periodontitis. …"