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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
Published 2023“…Interestingly, exosomal-PD-L2 expression was significantly higher (p=0.0193) in tissue PD-L1-negative patients compared to tissue PD-L1-positive patients. We have also shown that immuno-oncological proteins isolated from pre-ICIs treated patients were significantly higher in exosomes compared to their soluble-free counterparts (CD152, p=0.0008; CD80, p=0.0182; IDO, p=0.0443; Arginase, p<0.0001; Nectin-2, p<0.0001; NT5E, p<0.0001; Siglec-7, p<0.0001; Siglec-9, p=0.0335; CD28, p=0.0092; GITR, p<0.0001; MICA, p<0.0001). …”
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
Published 2024“…The global all-age incidence rate of URIs decreased by 10·1% (–12·0 to –8·1) from 1990 to 2019. …”
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183
Hedonic valuation of land protection methods: implications for cluster development.
Published 2014“…The key findings of the study are: (i) proximity to national or state park land and to city or county open space has a significant positive impact on property values, while proximity to national forest land or to privately conserved land exhibits no significant effects; and, (ii) inclusion of a property within a cluster development decreases its value by 17 to 26 %. …”
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184
Acoustic radiation-free surface phononic crystal resonator for in-liquid low-noise gravimetric detection
Published 2021“…The proposed radiation suppression method using SPC can also be applied in other types of acoustic wave resonators. …”
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Bridging Innovation and Security: Advancing Cyber-Threat Detection in Sustainable Smart Infrastructure
Published 2025“…However, this evolution has also exposed smart devices to increasingly sophisticated cyber-threats, endangering the integrity of entire smart networks. …”
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging
Published 2001“…Our study group was divided into three groups: increased (n = 35), decreased (n = 53), and normal tone (n = 54). All three measurements of white matter in each of the three study groups were significantly below values for control children. …”
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187
Ionic electroactive hybrid transducers
Published 2017“…SWNT/RuO2 hybrid transducer has a strain rate of 2.5%/sec, and a maximum attainable peak-to-peak strain of 9.38% (+/- 2V). SWNT/PANI hybrid also increased both strain and strain rate but not as significant as with RuO2. …”
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188
An insight into thermal properties of BC<sub>3</sub>-graphene hetero-nanosheets: a molecular dynamics study
Published 2021“…It was found that Kapitza resistance increases upon an increase of defect density in the grain boundary. …”
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Solar cultivation of microalgae in a desert environment for the development of techno-functional feed ingredients for aquaculture in Qatar
Published 2022“…To improve annual biomass productivities, the effect of implementation of a simple ground heat exchanger for thermal regulation of raceway ponds was also studied. Biomass productivities increased significantly, during extreme seasons due to respective cooling and heating of the culture. …”
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190
Comparison of postoperative pain in children after maintenance anaesthesia with propofol or sevoflurane: a systematic review and meta-analysis
Published 2024“…Further, children in the sevoflurane group had higher odds of having higher pain scores (OR 3.18, 95% CI 1.83–5.53, I2=20.9%), and a 60% increase in the odds of requiring postoperative rescue analgesia compared with propofol (OR 1.60, 95% CI 0.89–2.88, I<sup>2</sup>=58.2%).…”
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Is extended hepatectomy for hepatobiliary malignancy justified?
Published 2004“…Multivariate analysis showed that a synchronous intraabdominal procedure was the only factor associated with an increased risk of morbidity (hazard ratio [HR], 4.9; P = 0.02). …”
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193
Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
Published 2006“…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …”
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194
Risk of post-ERCP pancreatitis with placement of self-expandable metallic stents
Published 2010“…When significant variables were added to a multiple-predictor regression model, the odds of PEP from SEMS placement increased to 6.8 (95% CI, 2.2, 21.4). However, the frequency of PEP was similar between covered (6.9%) and uncovered (7.5%) SEMSs (OR 0.9 [CI, 0.3-2.4]). …”
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195
Whom should we sense in “social sensing” - analyzing which users work best for social media now-casting
Published 2015“…<p>Given the ever increasing amount of publicly available social media data, there is growing interest in using online data to study and quantify phenomena in the offline “real” world. …”
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Road Accidents In Bangalore: A Report
Published 2015“…The absolute number of road accidents has also been growing at an alarming rate which reflects concomitant investment in road safety strategies coupled with rapid rate of motorisation. …”
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197
Brand–brand relational moments
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198
On the selection of constitutive equation for modeling the friction stir processes of twin roll cast wrought AZ31B
Published 2014“…On average, the ZA6 equation showed improvements in solution time by 5.4% as compared with the Johnson–Cook equation and almost identical solution time (0.9% increase) with that of the ST equation. This result indicates that the proposed equation is not numerically expensive and can be safely adopted in such FEM simulations. …”
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Evaluation of psychological distress, burnout and structural empowerment status of healthcare workers during the outbreak of coronavirus disease (COVID-19): a cross-sectional quest...
Published 2024“…In addition, the analysis showed that HCWs working in the COVID-19 areas experienced significantly higher symptoms of severe stress, anxiety, depression and higher levels of burnout compared to those working in other areas. The results also revealed that direct work with COVID-19 patients, lower work experience, and high workload during the outbreak of COVID-19 increase the risks of negative psychological consequences.…”
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Synthesis and analysis of silver–copper alloy nanoparticles of different ratios manifest anticancer activity in breast cancer cells
Published 2020“…Furthermore, we observed the cell death pathway by the apoptosis marker Annexin-V which showed non-significant results, while the exposure of AgCu-NP in MCF-7 cells leads to toxicity and also caused significant increase in MMP-9 level, which suggests the cell death may be associated with other pathways such as autophagy and oxidative stress related.…”