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larger decrease » marked decrease (Expand Search)
large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
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5621
Supplementary Material for: Hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-promoted PI3K-Akt signaling pathway
Published 2024“…Results: The biomarkers of microglia M1 polarization and pro-inflammatory cytokines were significantly increased in hypothyroidism mice brain; hypothyroidism could also repress the expression of BDNF and TrkB, and the anti-inflammatory cytokine such as IL-10. …”
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5622
DataSheet1_Transcriptomic and sugar metabolic analysis reveals molecular mechanisms of peach gummosis in response to Neofusicoccum parvum infection.zip
Published 2024“…Furthermore, weighted gene co-expression network analysis (WGCNA) identified two transcription factors, ERF027 and bZIP9, as central regulators in the downregulated and upregulated modules, respectively. …”
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5623
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5624
Interaction between bottom-up and top-down signals in the cortical column model.
Published 2025“…The input to L5 has a largely opposite effect compared to the input to L4: it decreases the activity of excitatory neurons in layers 2/3, 4 and 6. …”
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5625
9th International Conference on Engineering for Waste and Biomass ValorisationJune 27-30, 2022 Copenhagen, Denmarkwww.wasteeng2022.orgSection E10 - Enzymes in esterification proces...
Published 2025“…Ongoing work focuses on the NADES-substrate interaction.</p><p dir="ltr">[1]Paiva, A., Craveiro, R., Aroso, I., Martins, M., Reis, R. …”
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5626
Supplementary Material for: Ectopic ACTH-dependent Cushing’s syndrome Emerging at a Late Stage of a Mixed Histology Neuroendocrine Neoplasm: a case report
Published 2024“…Urinary free cortisol (UFC) measurement was 21-fold the upper limit of the reference range (3614.0 nmol/24h), and cortisol concentration did not decreases after 1mg-dexamethasone suppression test (1812 nmol/L for an expected value < 50 nmol/L), confirming the ACTH-dependent Cushing's syndrome (CS). …”
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5627
Additional file 6 of Impact of seat position on survival outcomes and anatomically specific severe injury patterns in four-wheeled motor vehicle accidents: a retrospective cohort s...
Published 2025“…An adjusted association of decreased risk of severe trauma (ISS of > 15) and severe chest injuries was observed regardless of sex differences. aAdjusted for age, sex, admission year, season, presentation time, presentation day, prehospital length of stay, vehicle configuration, collision type, seatbelt use, airbag deployment, and involvement in high-energy trauma. bGood model fit was verified by the Hosmer–Lemeshow test (p = 0.365); the c-statistic for the model was 0.795. cGood model fit was verified by the Hosmer–Lemeshow test (p = 0.361); the c-statistic for the model was 0.888. dGood model fit was verified by the Hosmer–Lemeshow test (p = 0.661); the c-statistic for the model was 0.841. eGood model fit was verified by the Hosmer–Lemeshow test (p = 0.478); the c-statistic for the model was 0.855. fGood model fit was verified by the Hosmer–Lemeshow test (p = 0.455); the c-statistic for the model was 0.838. gThe Hosmer–Lemeshow test p-value was < 0.001; the c-statistic for the model was 0.871. hGood model fit was verified by the Hosmer–Lemeshow test (p = 0.395); the c-statistic for the model was 0.818. iGood model fit was verified by the Hosmer–Lemeshow test (p = 0.763); the c-statistic for the model was 0.861. jGood model fit was verified by the Hosmer–Lemeshow test (p = 0.742); the c-statistic for the model was 0.851. kGood model fit was verified by the Hosmer–Lemeshow test (p = 0.785). …”
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5628
<b>Wind speed manipulation experimental data from the Community Land Model version 5 (CLM5)</b>
Published 2025“…All air forcing data had a temporal resolution of 6-hourly and a spatial resolution of 0.5° × 0.5°, and the simulation was conducted at 0.9° × 1.25° resolution. The atmospheric CO<sub>2</sub> concentration in the simulation was set to a constant value of 367 ppm (default value in the model) to exclude effects of the rising CO<sub>2</sub> concentration on GPP.…”
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5629
Data Sheet 1_hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways.doc
Published 2025“…Furthermore, both SDUY429 and SDUY436 remarkably suppressed the migration and invasion of MDA-MB-231 cells by downregulating the protein kinase B (AKT)/glycogen synthase kinase-3 beta (GSK3β)/β-catenin signaling pathway. …”
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5630
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5631
Supplementary file 1_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma...
Published 2025“…</p>Results<p>In ectopic endometria of AM, there was a significant increase in miR-21 mRNA expression as well as heightened activity within the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) signaling pathway. …”
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5632
Supplementary file 2_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma...
Published 2025“…</p>Results<p>In ectopic endometria of AM, there was a significant increase in miR-21 mRNA expression as well as heightened activity within the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) signaling pathway. …”
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5633
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5634
LRIG1 and CDK6 expression in the lateral ventricular wall cells
Published 2025“…., presumptive C type transit amplifying cells), they proliferated and formed large neurospheres in single cell or bulk cultures. …”
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5635
Habitat suitability index (HSI) trend (seasonal and random components removed) time-series and Time of Emergence (ToE; vertical lines) for changes in HSI within CCE shelf-outer slo...
Published 2025“…<p>Both NMS & WEAs are arranged by decreasing latitude from top to bottom. ToE represents the first date where the HSI trend value is below one standard deviation of the mean HSI from the historical period (1985-2015).…”
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5636
Table 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.xlsx
Published 2025“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”
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5637
Table 2_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.xlsx
Published 2025“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”
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5638
Image 2_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif
Published 2025“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”
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5639
Image 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif
Published 2025“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”
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5640
Visualization of the logistic regression model.
Published 2025“…The color intensity, varying smoothly from red to blue, signifies the increasing or decreasing nature of the feature’s value, where red denotes a higher value while blue indicates a lower one. …”