Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
Get full text
Get full text

Flexural Capacity of Sustainable RC Beams Manufactured with Treated Wastewater, RCA, and Fly Ash by Abushanab, Abdelrahman

“…In addition, TWW and RCA decreased the beams' ductility by 10% and 16%, respectively. …”
Get full text
Get full text

MODELING AND OPTIMIZATION OF DISTRICT COOLING SYSTEM by ISMAEN, RABAH

“…This research focuses on modeling and optimization of the design and operation of a district cooling system (DCS). The research investigates two solution paths: (1) the system transformation leading to re-organizing the conventional system (powered by the grid electricity) to achieve better economic and energy performance, and (2) the system integration of solar cooling technologies to enhance sustainable development for decreasing CO2 emissions. …”
Get full text

Short-term effects of warming treatment and precipitation manipulation on the ecophysiological responses of pinus densiflora seedlings by Yun, Soon Jin

Get full text
Get full text

An efficient green ionic liquid for the corrosion inhibition of reinforcement steel in neutral and alkaline highly saline simulated concrete pore solutions by Sliem, Mostafa H.

“…The inhibition efficiency was improved as the concentration of Q-32 and pH values were increased. However, it decreased as the temperature was raised. A Q-32 concentration of 20 µmol L–1 exhibited a 94% inhibition efficiency at 20 °C. …”
Get full text
Get full text
Get full text

Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling by Ghantous, Crystal M.

“…Stretching the RPV for 10 minutes significantly decreased phosphorylation of LKB1, AMPK, and eNOS, while APN significantly increased p-LKB1, pAMPK, and p-eNOS in stretched vessels. …”
Get full text
Get full text

Mobility Competitiveness and Security: Expatriate Perspectives from Qatar by Ewers, Michael Christopher

“…Attracting the right mix of expatriates and retaining the best ones, however, is a major challenge for economy with a highly ambitious post-oil agenda, located in an unstable region, and where over 90% of workers are both foreign and temporary. …”
Get full text
Get full text

Enhancing compressive, tensile, thermal and damping response of pure Al using BN nanoparticles by Penchal Reddy M.

“…In the present study, aluminum based metal matrix composites containing various amounts of boron nitride (BN) nanoparticulates (0, 0.5, 1.0 and 1.5 vol.%) were fabricated by using the powder metallurgy (PM) technique involving microwave sintering and hot extrusion process. …”
Get full text
Get full text

The nexus between debt structure, firm performance, and the financial crisis: non-linear panel data evidence from Japan by Zeitun, Rami

“…This study seeks to analyze the non-linear relationship between a firm's debt structure and performance based on evidence from Japan through the use of a panel data fixed effects model for a sample of 1,670 listed firms. …”
Get full text
Get full text

Conjugated Linoleic Acid (CLA) co-treatment alleviates antidiabetic drug, rosiglitazone associated deterioration of bone remodeling by Ibrahim, Khadega

“…Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia due to decreased insulin secretion, defective action or both. …”
Get full text
Get full text

Self-healing performance of smart coatings modified with different corrosion inhibitors. by Habib, Sehrish

“…Corrosion results in considerable materials and equipment failure. According to one survey, about 1/4 to 1/3 of the total interruption in industries is due to detrimental effects of corrosion. …”
Get full text
Get full text

Adaptative Network Topology for Data Centers by Chkirbene, Zina

“…In addition, and thanks to the proposed fault tolerant algorithm, the new architecture shows a great performance even when the failure rate equals to 0.3, which means when about one third of the links failed, the connection failure rate is only 15%. …”
Get full text
Get full text

Nanocomposite Ni-TiO2 coatings produced by pulsed electroplating by Wang, Y.

“…Nanocomposite Ni-TiO2 coatings were prepared on mild steel substrate by pulse electroplating with controlled duty cycle and frequency. A systematic study of Ni-xTiO2 coatings with different TiO2 concentrations (x50-20 g L-1) has been conducted. …”
Get full text
Get full text

Nutritional quality and health risk of pepper fruit as affected by magnesium fertilization. by Lu, Ming

“…As a result, Mg fertilization decreased the comprehensive nutrition level of pepper by 16.6%. …”
Get full text
Get full text

Role of TiO2 and carbon nanotubes on polyethylene, and effect of accelerated weathering on photo oxidation and mechanical properties by Zagho M.M.

Get full text
Get full text

Event-triggered based consensus of autonomous underactuated surface vessels by Mirzaei, Morteza

“…Furthermore, agents broadcast their information based on predefined event triggering conditions and the amount of data exchange among the surface vessels is significantly decreased. To illustrate the performance of the proposed approach, simulation results are provided. 1 2017 IEEE.…”
Get full text
Get full text

Effect of the induced dielectrophoretic force on harvesting of marine microalgae (Tetraselmis sp.) in electrocoagulation by Hawari, Alaa H.

“…The impact of electrode configuration, current density and electrolysis time were evaluated. A maximum algal harvesting efficiency of 90.9% was achieved using 7.1 mA/cm2 current density and 10 min electrolysis time. …”
Get full text
Get full text

Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells by AlKahlout, Amal

“…Here, we show that in MDA-MB-231, a TNBC cell line, Origanum syriacum L. aqueous extract (OSE) inhibited cellular viability, induced autophagy determined by the accumulation of lipidized LC3 II, and triggered apoptosis. …”
Get full text
Get full text
Get full text

Plasma volume variations in response to high intensity interval training in obese women: The influential role of menopausal status and age by Jabbour, Georges

“…Multiple linear regression analysis revealed that age was a significant contributor to the decreases in plasma volume (PV) observed both after warm-up and following the supramaximal cycling test - SCT (r = 0.44 and r = 0.57). …”
Get full text
Get full text
Get full text

Surfactant for Enhanced Rheological, Electrical, and Electrochemical Performance of Suspensions for Semisolid Redox Flow Batteries and Super capacitors by Madec, L.

“…A suspension of Li4Ti5O12 and of Ketjen black in a solution of 1?…”
Get full text
Get full text